MARINE INGREDIENTS


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Fucoidan: A future in balancing skin microbiome


Krutika Sen - Marinova, Australia


Fucoidan is a long-chain polysaccharide found naturally in brown seaweeds. On the back of extensive immuno-modulatory, anti- inflammatory, digestive health and anti-cancer research, fucoidan is increasingly being utilised in a range of dietary supplements. In recent years, mounting anti-ageing evidence has also placed this novel marine ingredient on the radar of skin care formulators. High purity, certified organic


fucoidan ingredients with global regulatory acceptance are rapidly rising to the forefront of the blue beauty movement. Not only do they tick all the right boxes in terms of sustainability and ethical sourcing but also in terms of efficacy and ease of formulation. The potential benefits of fucoidan on skin health are increasingly being reported in scientific literature and are capturing the attention of some the world’s leading skin care brands. Fucoidan’s role in nature is to protect


the seaweed against a range of external stresses, including environmental pathogens. Australian biotechnology company Marinova was the first to capture these natural benefits for topical use, launching two high purity fucoidan extracts onto the global skin care market over a decade ago. Backed by clinical evidence, Maritech® Bright, derived from Fucus vesiculosus seaweed, and Maritech Reverse, derived from Undaria pinnatifida seaweed, both offer profound anti- ageing properties.1


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Central to the efficacy of this ingredient is its proven ability to inhibit elastase, collagenase and tyrosinase – key enzymes known to accelerate the visible signs of ageing.1


A brightening, anti- ageing & antioxidant combination Maritech Bright (now referred


to as ‘the Fucus vesiculosus seaweed complex’) is a highly characterised, certified organic fucoidan-polyphenol complex sourced from wild- grown Fucus vesiculosus seaweed. It is a clinically proven brightening ingredient with class-leading antioxidant activity to protect skin from the damaging effects of free radicals. Clinical studies have shown that the Fucus vesiculosus seaweed complex is safe, non-sensitising and highly effective at brightening skin. It enhances radiance and visibly reduces age spot pigmentation.


Protecting & soothing properties The award-winning Maritech Reverse (now referred to as ‘the Undaria pinnatifida seaweed ingredient’) is sourced from wild grown Undaria pinnatifida seaweed. It is proven to have natural protecting and soothing effects, maintaining the youthful appearance of skin by protecting its building blocks and enhancing dermal condition. Alongside its ability to boost defence mechanisms by up to 387%, it has been shown to reduced redness by 45% following UV exposure, increase moisture retention by up to 30%, soothe skin by inhibiting enzymes associated with oxidative stress and inflammation by up to 99%, and activate key restorative genes within the skin.1


Investigating skin microbiome Skin microbiota is believed to play an important role in the management of healthy skin. When the balance of microorganisms is disturbed, and harmful bacteria outnumber helpful bacteria, the skin can become vulnerable to a variety of unfavourable conditions. In recent years the effects of fucoidan on microbiome has been identified as an emerging area of focus.2


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recent in vitro study investigated the effect of high purity fucoidan on the adhesion of three common skin bacteria.3


The fucoidan extracts


utilised in the study were the proprietary commercial extracts, the Fucus vesiculosus seaweed complex and the Undaria pinnatifida seaweed ingredient described above. In addition to examining bacterial adhesion,


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the study also investigated the potential effects of the Fucus vesiculosus seaweed complex and the Undaria pinnatifida seaweed ingredient on gene expression in a 3D model of atopic dermatitis (AD), the most common form of eczema. Chronic inflammatory skin conditions like


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eczema can be debilitating for up to 20% of children and approximately 10% of adults.4


0 Control Maritech Bright Maritech Reverse Figure 1: Concentrations of adherent S. aureus after topical treatment with Maritech fucoidan www.personalcaremagazine.com The


combined results are of particular interest to those searching for new therapeutic treatments for inflammatory skin conditions. There is currently an unmet global need for effective, non-toxic, topical treatments that may assist in offering relief to millions of sufferers across the globe.


November 2021 PERSONAL CARE


Adherent cells (CFU/RHE)


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