COVER STORY: LIPOID KOSMETIK ADVERTISEMENT FEATURE The anti-wrinkle effect was determined by
single fold-depth measurements in the eye area and visually with standardized photographs. Moreover, the opinion of the consumers was evaluated with a questionnaire-based survey. After 28 days, single fold-depth of wrinkles
was reduced by 26 %. The measured reduction is supported by a visible anti-wrinkle effect and a healthier and glowing complexion (Figure 4). The cosmetic benefits were confirmed by the consumers that reported a reduction of wrinkles (70%), a healthier and glowing complexion (80%), and a good or very good skin feel (85%). All participants reported a good or very
good tolerability which was in accordance with the positive evaluation by the dermatologist. Moreover, 75% of the participants would recommend PhytoSolve® Astaxanthin (data not shown).
Conclusion PhytoSolve® Astaxanthin showed excellent cosmetic benefits. The antioxidant effect and capability to mitigate UVB-induced skin damage was proven in vitro. A study with volunteers showed a pronounced and visible anti-wrinkle effect. In addition, the volunteers judged the
product as highly attractive with a good skin feel and reported a rejuvenated skin appearance and a healthier and glowing complexion. Overall, PhytoSolve® Astaxanthin is an
excellent anti-ageing product and a perfect component for advanced skin care products, providing a synergistic complex between natural phospholipids and the powerful antioxidant AXN.
Ingredients (INCI) Glycerin, Aqua (Water), Caprylic/Capric Triglyceride, Lecithin, Haematococcus Pluvialis Extract, Tocopherol, Sodium Chloride, Sodium Hydroxide, Helianthus Annuus (Sunflower) Seed Oil.
References 1. Nishida Y, Yamashita E et al. Quenching activities of common hydrophilic and lipophilic antioxidants against singlet oxygen using chemiluminescence detection system. Carotenoid Science. 2007; 11, 16-20 2. Van Hoogevest P, Fahr A. Phospholipids in
Results
700 600 500 400 300 200 100 0
Day 0
Figure 2: Representative cream formulations containing PhytoSolve® Astaxanthin in concentrations of 0.1 to 2%
Results
175 150 125 100 75 50 25 0
Placebo ■ PhytoSolve® Astaxanthin ■ *
+48% +25%
7
10 min
30 min
Figure 3: SAP values of a formulation with 10% PhytoSolve® Astaxanthin in relation to the placebo formulation after 10 and 30 minutes of incubation (n = 4-5 ± SD, *p < 0.05)
cosmetic carriers. Nanocosmetics. 2019; 95-140 PC
3. Jung K, Sacher M et al. Anti-aging status of skin characterized by the skin antioxidative protection SAP – Efficacy of topically applied antioxidants. SÖFW-Journal. 2006; 132(9)
4. Berridge MV, Tan AS et al. The biochemical and cellular basis of cell proliferation assays that use tetrazolium salts. Biochemica. 1996; 4(1), 14-19
Lipoid Kosmetik AG Sennweidstr. 44/46 6312 Steinhausen Switzerland Tel: +41 (0) 41 748 33 33
https://www.lipoid-kosmetik.com/
info@lipoid-kosmetik.com
-26%
Day 28
Day 0
www.personalcaremagazine.com
Day 28 Figure 4: Single fold-depth in the test area before and after applying a cosmetic formulation with 2% PhytoSolve® Astaxanthin twice daily for 28 days (n=20 ± SD) June 2024 PERSONAL CARE
Single fold-depth (µm)
Relative Skin Antioxidant Potential (%)
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