NATURALS A
0% -5%
-10% -15%
-20% -25% -30%
Sebum ■ Open Comedones ■ Papules ■ B C
51
-19% -24% -25%
Figure 6: (A) Cleansing AHE 1.5% after 21 days; sebum production - 22%, open comedones -19% and papules -24%. (B) Acne lesions (Visia) untreated. (C) Acne lesions (Visia) treated AHE 1.5% after 21 days
7. Montuschi P, Barnes PJ, Roberts LJ 2nd. Isoprostanes: markers and mediators of oxidative stress. FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol. 2004; Dec;18(15):1791–800
8. Shim JH. Prostaglandin E2 Induces Skin Aging via E-Prostanoid 1 in Normal Human Dermal Fibroblasts. Int. J. Mol. Sci. 2019; Nov 7;20(22):5555
9. Peiris H, Dubach D, Jessup CF, Unterweger P, Raghupathi R, Muyderman H, et al. RCAN1 regulates mitochondrial function and increases susceptibility to oxidative stress in mammalian cells. Oxid. Med. Cell. Longev. 2014/06/09. 2014;2014:520316.
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% of reduction in mean
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