NATURALS
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PRODEW600
Amino acid mixture designed for skincare, hair care and make up
For efficient supplement of amino acids
Premixed solution of high -quality amino acids
PRODEW500 Figure 9: Concept and application of Prodew series
± 5%) without any application after the last face wash. The subjects were 22 women in 30s to 50s with wrinkle grades 1 to 3. Based on the anti-wrinkle product
evaluation guidelines of the Japan Cosmetics Society, wrinkle grades 0 (no wrinkle) to 7 (very deep wrinkles) were evaluated visually by an experienced evaluator. Figures 7 and 8 show changes in wrinkle grade during continuous use and a photo of the appearance after three months of continuous use. It was found that continuous use of PCA Zn improved the appearance of wrinkles.
Amino acid mix combining fermentation-derived amino acids As mentioned above, it has been reported that amino acids and amino acid derivatives permeate into the stratum corneum and improve moisturizing properties when NMF components are applied externally.3 Amino acid mixtures can also be useful
raw materials for personal care products. NMF compositions contain more than ten types of amino acids, and some amino acids can take time to dissolve when preparing cosmetic formulations, so aqueous solutions of amino acid mixes (Prodew™ series) have been commercialized.
The main amino acids and amino acid
derivatives of the Prodew series are derived from fermentation and are used for skin care (600), hair care (500), and makeup products (700) depending on the application and concept. Amino acid composition has been optimized for each application. Figure 10 shows the effect of improving the shine of hair strands when applying 500. Hair of a Japanese woman that was bleached four times was soaked in 100g of an aqueous solution containing 2 wt.% or 5 wt.% of the product at 35°C for ten minutes, and then rinsed in ion-exchanged water at 35°C for one minute. It was visually confirmed that the shine of the hair strands soaked in the amino acid mix was
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40 30 20 10
0% 2% Addition amount of PRODEW500 Figure 10: Effect of improving hair gloss with Prodew 500
improved, and the gloss index, measured using a goniophotometer, was also improved. Next, we introduce Prodew 700 for makeup
products. There is a strong need of a long- lasting effect to enjoy makeup products stress- free. On the other hand, when focusing on the skin, makeup cosmetics cover the bare skin with various mixtures (oils, surfactants, powders) for a long time, so some consumers feel that makeup cosmetics burden their skin condition. Many consumers remove their makeup when they get home, and makeup cosmetics
are generally not thought to actively improve skin conditions. Therefore, we have developed an amino acid mix that both improves the long- lasting effect and improves the condition of the skin when using makeup. Figure 11 shows the changes in skin
capacitance and trans epidermal water loss (TEWL) on bare skin after repeated use of BB cream containing the product. The evaluation was carried out over a four-week period during the winter season, and after morning skin care, the subject applied the test sample of BB
June 2024 PERSONAL CARE n=3, mean±S.D. PRODEW700
5%
Gloss Index (%)
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