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SKIN MICROBIOME Before use After 4 weeks


67


Dandruff


Figure 11: Observation of scalp


containing 1% Aminoflora (Figure 10). Twenty-two subjects used the shampoo and conditioner daily for four weeks. Before and after four weeks, the scalp was observed to confirm the presence or absence of dandruff. Comparing images of the scalp before and


after using shampoo containing Aminoflora, we found that dandruff was significantly reduced (Figure 11). Therefore, we believe that Aminoflora inhibits dandruff caused by dryness of the scalp due to shampooing. The scalp care effect of Aminoflora has also been confirmed.


Conclusion As the understanding of the skin microbiome deepens, it becomes clear that nurturing a balanced skin microbiome is vital for optimal skin health. Aminoflora emerges as a versatile and effective solution, not only regulating the balance of skin microbiome but also offering long-lasting moisturisation. By comprehensively addressing skin, scalp,


and hair health, Seiwa Kasei’s novel amino acid derivative Aminoflora, product name Amitose™ R-PD (INCI: Dihydroxypropyl Arginine HCl, Water), contributes to a holistic approach in advancing overall skin wellbeing.


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2. AL-Smadi K, Leite-Silva VR, Filho NA, Lopes PS, Mohammed Y. Innovative Approaches for Maintaining and Enhancing Skin Health and Managing Skin Diseases through Microbiome- Targeted Strategies. Antibiotics. 2023; 12, 1698


3. Scharschmidt TC, Fischbach MA. What lives on our skin: ecology, genomics and therapeutic


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opportunities of the skin microbiome. Drug Discovery Today: Disease Mechanisms. 2013; Volume 10, Issues 3–4, pages e83-e89


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Skin microbiome dysbiosis and the role of Staphylococcus aureus in atopic dermatitis in adults and children: A narrative review. J. Eur. Acad. Dermatol. Venereol. 2023; 37 Suppl 5:3- 17


13. Matsui K, Nishikawa A, Suto H, Tsuboi R, Ogawa H. Comparative study of Staphylococcus aureus isolated from lesional and non-lesional skin of atopic dermatitis patients. Microbiol Immunol. 2000; 44(11): 945–7


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8. Cros MP, Mir-Pedrol J, Toloza L et al. New insights into the role of Cutibacterium acnes- derived extracellular vesicles in inflammatory skin disorders. Sci. Rep. 2023; 13, 16058.


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PC


10. Landemaine L, Da Costa G, Fissier E, Francis C, Morand S, Verbeke J, Michel M-L, Briandet R, Sokol H, Gueniche A, Bernard D, Chatel J-M, Aguilar L, Langella P, Clavaud C, Richard ML. Staphylococcus epidermidis isolates from atopic or healthy skin have opposite effect on skin cells: potential implication of the AHR pathway modulation. Front. Immunol. 2023; 14:1098160


11. Sugimoto S, Iwamoto T, Takada K, Okuda K, Tajima A, Iwase T, Mizunoe Y. Staphylococcus epidermidis Esp degrades specific proteins associated with Staphylococcus aureus biofilm formation and host-pathogen interaction. J. Bacteriol. 2013; 195(8):1645-55


12. Demessant-Flavigny AL, Connétable S, Kerob D, Moreau M, Aguilar L, Wollenberg A.


14. Saxena R, Mittal P, Clavaud C, Dhakan DB, Hegde P, Veeranagaiah MM, Saha S, Souverain L, Roy N, Breton L, Misra N, Sharma VK. Comparison of Healthy and Dandruff Scalp Microbiome Reveals the Role of Commensals in Scalp Health. Front. Cell. Infect. Microbiol. 2018; 8:346


15. Hamdino M, Saudy AA, El-Shahed LH, Taha M. Identification ofMalassezia species isolated from some Malassezia associated skin diseases. Journal of Medical Mycology, 2002; 32 (4)


16. Polak-Witka K, Rudnicka L, Blume-Peytavi U. Vogt A. The role of the Microbiome in scalp hair Follicle biology and disease. Experimental Dermatology 2020; 29:286–294


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20. Agari Y. Functions required for moisturizer. Fragrance Journal. 2020; 48 (1) 44-49


June 2024 PERSONAL CARE


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