TRENDING TECHNOLOGIES


(Rz) compared to the placebo treatment by around 10%. The results achieved by the biomimetic


hydroxyapatite in the previously mentioned tests confirm its suitability for inclusion in multi- functional sunscreens as well as in products for skin protection and anti-ageing claiming SPF, in line with the trends highlighted earlier in this article.


Conclusion Sunscreens market has experienced a consistent increase of interest toward the use of mineral filters and boosters as well as ingredients with multifunctional features, high naturalness, sustainably sourced and with low environmental impact. Apalight biomimetic HAP is a specialty


ingredient based on a mineral comparable to that occurring in the human body and in the sea ecosystem. This specific type of mineral is traditionally used in medical applications (as coating to promote bone ingrowth into prosthetic implants, and as a rejuvenating solution in aesthetic medicine etc.). It represents an interesting innovation for sun care, as it enables the formulation of fully natural mineral sunscreens with optimized sensorial features and hybrid sunscreens in combination with organic filters to achieve high SPF protection values. HAP mineral does not give any applicative


whitening effect and shows a light texture that drastically differentiates it from micron sized inorganic filters, enabling to either reduce their amount in mineral sunscreens or totally replace them in hybrid sunscreens. Furthermore, its biomimetic nature, its peculiar external surface and pH dependent oligoelements release triggered by skin acidic values promote multiple benefits, including elasticity enhance, maintenance of skin barrier integrity and anti-wrinkle features. In the wake of the studies previously shown,


biomimetic HAP represents therefore a promising candidate for the development of heterogeneous multifunctional sun care products in the name of environmental sustainability.


PC


References 1. Haywood R, Wardman P, Sanders R, Linge C. Sunscreens inadequately protect against ultraviolet-A-induced free radicals in skin: implications for skin aging and melanoma? J Invest Dermatol. 2003 Oct. 121(4). P: 862-8


2. Nohynek GJ, Schaefer H. Benefit and Risk of Organic Ultraviolet Filters. Regulatory Toxicology and Pharmacology. 2001. 33. P: 285-299


3. Nery EM, Martinez RM, Velasco, MVR, Baby, AR. A short review of alternative ingredients and technologies of inorganic UV filters. J Cosmet Dermatol. 2020. 20(4). P:1061-1065


4. Shanbhag S, Nayak A, Narayan R, Nayak UY. Anti-aging and Sunscreens: Paradigm Shift in Cosmetics. Adv Pharm Bull. 2019. 9(3). P:348-359


5. Collaris EJ, Frank J. Photoallergic contact dermatitis caused by ultraviolet filters in different sunscreens. Int. J. Dermatol. 47, 35–37. 2008


www.personalcaremagazine.com


SKIN ELASTICITY (R2) (CUTOMETER SEM 575, COURAGE & KHAZAKA)


T0 ■ T4 weeks ■


0.64 0.62 0.6


0.58 0.56 0.54 0.52


Apalight cream Placewbo


0.25 0.2


0.15 0.1


0.05 0


Apalight cream Placewbo


Figure 4: Hydroxyapatite four-week treatment results: +10.3% elasticity, -17.1% viscoelasticity (increased firmness)


6. Butt ST, Christensen T. Toxicity and photo- toxicity of chemical sun filters- Radiation Protection Dosimetry Nuclear Technology Publishing Vol. 91, Nos 1–3, pp. 283–286. 2000


7. Couteau C, Pommier M, Paparis E, Coiffard LJM. Study of the efficacy of 18 sun filters authorized in European Union tested in vitro- Pharmazie. 2007. DOI: 10.1691/ ph.2007.6.6247


8. Díaz-Cruz MS, Llorca M, Barceló D. Organic UV filters and their photodegradates, metabolites and disinfection by-products in the aquatic environment. Trends in Analytical Chemistry. 2008. 27(10). P: 873- 887


9. Ramos S, Homem V, Alves A., Santos L. A review of organic UV-filters in wastewater treatment plants. Environmental International. 2016. 86. P: 24-44


10. Gilbert E, Pirot F, Bertholle V, Roussel L, Falson F, Padois K. Commonly used UV filter toxicity on biological functions: review of last decade studies. International Journal of Cosmetic Science. 2013. 35. P: 208-219


11. Lademann J, Schanzer S, Jacobi U, Schaefer H, Pflucker F, Driller, H, Beck J, Meinke M, Roggan A, Sterry W. Synergy effects between organic and inorganic UV filters in sunscreens. Journal of Biomedical Optics.2005. 10(1). P: 014008-1-7


DEEP WRINKLE (RZ) SKIN SURFACE REPLICA AND SURFACE ANALYSIS (MONADERM, MONACO)


T0 ■ T4 weeks ■


60 59 58 57 56 55 54 53 52 51 50


Apalight cream Placewbo


Figure 5: Hydroxyapatite four-week treatment results: -10% deep wrinkles


12. Di Gesu R. Global Beauty & Personal Care Analyst - A year of innovation in suncare. 2021


13. Future Market Insights. Mineral Sunscreen Market. July 2020


14. Adler LB, DeLeo VA. Sunscreen Safety: a Review of Recent Studies on Humans and the Environment. Springer. March 2020. Current Dermatology Reports 9(3s1). DOI:10.1007/s13671-020-00284-4


15. Fact MR. Sun Protection Products Market. March 2022


16. Von Euw S, Wang Y, Laurent G, Drouet C, Babonneau F, Nassif N, Azaïs T. Bone mineral: new insights into its chemical composition. Nature Scientific Reports. Volume 9. Article number: 8456 (2019)


17. Legeros RZ, Legeros JP. In: Kokubo T (Ed.) Bioceramics and their clinical applications. Woodhead Publishing. 2008.


18. Kattimani Kondaka S, Lingamaneni KS. Hydroxyapatite - Past, Present, and Future in Bone Regeneration. Bone and Tissue Regeneration Insights. 2016:7 9–19. DOI: 10.4137/BTRI.S36138


19. Daugaard H, Elmengaard B, Bechtold JE, Jensen T, Soballe K. The effect on bone growth enhancement of implant coatings with hydroxyapatite and collagen deposited electrochemically and by plasma spray. J Biomed Mater Res A. 2010 Mar 1; 92(3): 913–921. DOI: 10.1002/ jbm.a.32303


20. Kawamata H, Fujita K, Ishizaki T, Hayman R, Kemi T. A now enamel restoring agent for use after bleaching. Journal of Dental Research. 2004. 83


21. Kaji F, Nakagawa S, Matsuda N, Watanabe M. The adsorption of unsaturated fatty acid on hydroxyapatite, Phosphorus Research Bulletin. January 2005. 19:147-151 DOI: 10.3363/prb1992.19.0_147


22. Tomoda K, Ariizumi H, Nakaji T, Makino K. Hydroxyapatite particles as drug carriers for proteins Colloids Surf B Biointerfaces. 2010 Mar 1;76(1):226-35. doi:10.1016/ j.colsurfb.2009.10.039. Epub 2009 Nov 1


23. Pal A, Hadagalli K, Bhat P, Goel V, Mandal S. Hydroxyapatite—a promising sunscre en filter. J Aust Ceram Soc. 2020. 56. P: 345-351


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VISCO-ELASTICITY (R6) (CUTOMETER SEM 575, COURAGE & KHAZAKA)


T0 ■ T4 weeks ■


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