TRENDING TECHNOLOGIES Area (mm2 0%
-2% -4% -6% -8%
-10% -12% -14% -16% -18%
-2.0%
H.Basil vs Placebo p<0.05
-1.8%
H.Basil vs Placebo p<0.05
)
Holy basil■ Placebo ■ Length (mm)
0%
-2% -4% -6% -8%
-15.2% *
-15.7% *
Figure 13: Illustration of the effect of the active ingredient on crow’s feet wrinkles
Anti-ageing effect on biomechanical properties and effect on complexion colour and uniformity The polyphenols significantly improved skin tone and elasticity at D28 and D56. Holy basil polyphenols significantly improved complexion uniformity at D56. Holy basil polyphenols reduce the surface
and length of crow’s feet and forehead wrinkles, preserve skin elasticity, and better the skin’s complexion. They have therefore a noticeable anti-inflammaging potential.
Conclusion To conclude, the holy basil polyphenols concentrate benefits from the adaptogenic plant Ocimum sanctum, which counter damages caused by the exposome, psychological and environmental effects, and therefore bring to the skin’s firmness an anti- wrinkle and shiny effect.
References 1. Franceschi C et al. Acad Sci. 2000. Jun; 908():244-54
2. Sun N et
al.Mol Cell.2016- 5:Vol. 61 pp. 654–666
3. Valacchi G et al. Antioxidants & Redox Signaling. 2020. 4: Vol. 33. pp. 308–326
4. Krutmann J et al. Journal of Dermatological Science. 2016. 3:Vol. 85. pp. 152-161
5. Valacchi G et al. Frontiers in Physiology. 2018. Vol. 9 pp. 1-15
6. Pilkington SM et al. Journal of Investigative D0
D0
-10% -12% -14%
Area (mm2 ) Length (mm)
67 J28■ J56 ■
-7.2%
-7.0%
Figure 14: Illustration of the effect of the active ingredient on forehead wrinkles
-13.3% *
D56
-13.2% *
Figure 15: Illustration of the effect of the active ingredient on crow's feet wrinkles D0 and D56 Dermatology. 2021
PC
7. Singh K. Plastic and Reconstructive Surgery. 2021. Vol. 147. pp. 33S-37S
8. Jang JY et al. The Journal of Clinical Investigation. 2018. 9: Vol. 128. pp. 3662-3670
9. Baylis D et al. Understanding how we age: insights into Inflammaging [Review]. Longevity & Healthspan. 2013. Vol. 2. p. 8
10. Daubree A. Le nouvel eldorado des peaux matures. N°65 Expression Cosmétique. Sep- Oct 2020, pp 20
11. Loor G et al. Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis [Review]. Free Radic Biol Med. 2010. 12: Vol. 49. pp. 1925-1936
D0
12. Krutmann J et al. The skin ageing exposome [Review]. Journal of Dermatological Science. 2016. 3: Vol. 85. pp. 152-161
13. Bruch-Gerharz D, Ruzicka T, Kolb-Bachofen V. Nitric Oxide in Human Skin: Current Status and Future Prospects [Review]. Journal of Investigative Dermatology. 1998. Vol. 110. pp. 1-7
14. Fivenson EM et al. Mitophagy in neurodegeneration and ageing [Review]. Neurochem Int. - 2017. Vol. 109. pp. 202–209
15. Jeong D et al. The role of autophagy in skin fibroblasts, keratinocytes, melanocytes and epidermal stem cells [Review]. Journal of Investigative Dermatology. 2020. Vol. 140. pp. 1691-1697
D56
D56
Figure 16: Illustration of the effect of the active ingredient on forehead wrinkles D0 and D56
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Figure 17: Reduction of red blotches on the skin June 2022 PERSONAL CARE
Evoltion %
Evoltion %
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