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48 MARINE INGREDIENTS


can lead to negative acute and long term health indications, including erythema, photo-ageing, photo-immunosuppression and skin cancers.10


However, antioxidants


can protect the skin against UV damage by neutralising free radicals that cause tissue damage and skin blemishes.


Due to its high content of polyphenol compounds, Fucus vesiculosus extract is a potent antioxidant with a very high oxygen radical absorbance capacity (ORAC 6.0) of 28,689 TE/g. Over 80% of this activity is attributed to its powerful effects against ‘superoxide’ - the most damaging free radical that is a precursor to other reactive species. In vitro studies show that Fucus vesiculosus extract combats oxidative stresses with antioxidant activity that is – gram for gram – double that of vitamin C.


Increased protein expression Research has shown that Fucus vesiculosus extract can increase the expression of the anti-ageing protein SIRT1. SIRT1 is associated with genes that coordinate and optimise the functions of cells as they struggle to survive in stressful environments. An increase in the expression of SIRT1 is known to activate key anti- ageing mechanisms, including those that promote healthy, radiant skin.11


In vitro


studies have shown that Fucus vesiculosus extract can increase the expression of SIRT1 by 32%.


Non-sensitising and non allergenic Extensive clinical testing has validated Marinova’s Fucus vesiculosus extract to be non-sensitising and non allergenic. This ingredient is safe to apply topically at high concentrations, although clinical testing demonstrates effective bioactivity at a very low concentration of 0.3 % w/v.


Organic and sustainable


The Maritech cosmetic range stands alone as the only certified organic fucoidan cosmetic ingredients. The cosmetic ingredients are certified organic with


4000 3000 2000 1000 0 Vitamin C Figure 4: Antioxidant power. PERSONAL CARE EUROPE Maritech Bright


Australian Certified Organic (ACO), Cosmetic Organic and Natural Standard (COSMOS) and the United States National Organic Program (NOP). The wild-harvest non-GMO nature of the seaweed is also certified and preserved throughout the Maritech process, delivering a non-GMO certification to this highly active natural product. These exclusive attributes are credited to the pure source and green chemistry technology from which the Maritech ingredients are derived. Marinova is a fervent protector of the marine environment and exemplifies sustainable practices in every element of the production of its fucoidan ingredients. Since establishing its state of the art extraction facility, the company has succeeded in diverting all seaweed residues away from unproductive landfill and into new, value-added products. Seaweed not utilised for the extraction of high-purity fucoidan compounds is sold by the company into the gourmet and wholefoods sectors. Both liquid and solid by-products of the extraction process are captured and converted into nutrient-rich organic additives for the horticultural sector. In doing so, the company is on the cusp of becoming a legitimate environmentally sustainable, zero-waste manufacturer. Marinova’s facilities are registered with the US FDA, are ISO9001 certified for quality management and HACCP with GMP


certification. The company also holds Australian Trusted Trader and Known Consignor status with the Australian Border Force. Marinova’s Fucus vesiculosus extract is marketed and distributed internationally as Luminact Brite by global speciality chemicals company, Innospec.


PC


References 1 Ruocco N, Costantini S, Guariniello S et al. Polysaccharides from the Marine Environment with Pharmacological, Cosmeceutical and Nutraceutical Potential. Molecules 2016; 21: 551


2 Fitton JH, Stringer D, Karpiniec S. Therapies from Fucoidan: An Update. Mar. Drugs 2015; 13: 5920-5946


3 Draelos, ZT. Cosmeceuticals: Procedures in Cosmetic Dermatology Series; Elsevier Sauders: Philadelphia, PA, USA, 2014.


4 Fitton JH, Dell’Acqua G, Gardiner, V et al. Topical Benefits of Two Fucoidan-Rich Extracts from Marine Macroalgae. Cosmetics 2015; 2: 66-81


5 Sanjeewa KKA, Kim EA, Son KT et al. Bioactive properties and potentials cosmeceutical applications of phlorotannins isolated from brown seaweeds: A review. J Photochem Photobiol B. 2016;162:100-105


6 Chavan M, Sun Y, Litchauer J et al. Fucus extract: cosmetic treatment for under-eye dark circles. J Cosmet Sci. 2014;65(2):103-13.


7 Senni K, Gueniche F, Foucault-Bertaud A et al. Fucoidan a sulfated polysaccharide from brown algae is a potent modulator of connective tissue proteolysis. Arch Biochem Biophys 2006; 445 (1): 56-64.


8 Turing TS, Hili P, Naughton DP. Anti- collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants. BMC Complement Altem Med 2009; 9: 27.


9 Kohl E, Steinbauer J, et al. (2011). Skin ageing. J Eur Acad Dermatol Venereol 2011; 25(8): 873-884


10 Marionnet C, Tricaud C, Bernerd F. Exposure to Non-Extreme Solar UV Daylight: Spectral Characterization, Effects on Skin and Photoprotection. Int J Mol Sci. 2015; 16(1): 68– 90.


11 Serravallo M, Jagdeo J, et al. Sirtuins in dermatology: applications for future research and therapeutics. Arch Dermatol Res 2013; 305(4): 269-282


June 2018


Trolox equivalents/g


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