EYE AREA CARE
subsequently determined that the patient was concomitantly applying different cosmetic lotions to the same tissue area. The Maher paper cited allergies at 5% as reported in a paper by Studdiford et al,19
however the
authors commented that this is infrequent if used in low [yet effective] concentrations.20
Conclusion Tea tree oil is an effective treatment for Demodex infestation as well as for general eyelid hygiene. Only pure tea tree oil that is not oxidised should be used. A GC-FID test to the ISO standard (4730: 2017), including a chiral ratio assessment, should be undertaken to confirm purity, and therefore safety and efficacy. Tea tree oil may be an effective ingredient for eyelid and eyelash washes to remove sources of inflammation such as bacteria, demodex, pollen, dirt, dust, makeup residue, and debris.
Demodex blepharitis: clinical perspectives. Clin Optom (Auckl). 2018;10:57-63. Published 2018 Jul 4.
6. Carson CF, Hammer KA, Riley TV. Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clin Microbiol Rev. 2006;19(1):50-62.
7. Gao YY, Di Pascuale MA, Li W, Baradaran-Rafii A, Elizondo A, Kuo CL, Raju VK, Tseng SC. In vitro and in vivo killing of ocular Demodex by tea tree oil. Br J Ophthalmol 2005;89:1468–1473.
8. Karakurt Y, Zeytun E. Evaluation of the Efficacy of Tea Tree Oil On the Density of Demodex Mites (Acari: Demodicidae) and Ocular Symptoms In Patients With Demodectic Blepharitis. J Parasitol. 2018;104(5):473-478.
PC
References 1. Liu J, Sheha H, Tseng SC. Pathogenic role of Demodex mites in blepharitis. Curr Opin Allergy Clin Immunol. 2010;10(5):505-510.
2.
https://www.aoa.org/ accessed 04 January 2021
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3. Liu J, Sheha H, Tseng SC. Pathogenic role of Demodex mites in blepharitis. Curr Opin Allergy Clin Immunol. 2010;10(5):505-10.
4. Liu J, Sheha H, Tseng SC. Pathogenic role of Demodex mites in blepharitis. Curr Opin Allergy Clin Immunol. 2010;10(5):505-510.
5. Fromstein SR, Harthan JS, Patel J, Opitz DL.
9. Ergun SB, Saribas GS, Yarayici S, Elmazoglu Z, Cardak A, Ozogul C, Ilhan MN, Karasu C, Evren Kemer O. Comparison of Efficacy and Safety of Two Tea Tree Oil-Based Formulations in Patients with Chronic Blepharitis: A Double- Blinded Randomized Clinical Trial. Ocul Immunol Inflamm. 2020;17;28(6):888-897.
10. Tighe S, Gao YY, Tseng SC. Terpinen-4-ol is the Most Active Ingredient of Tea Tree Oil to Kill Demodex Mites. Transl Vis Sci Technol. 2013;2(7):2.
11. Gonzalez-Hinojosa D, Jaime-Villalonga A, Aguilar-Montes G, Lammoglia-Ordiales L. Demodex and rosacea: Is there a relationship?. Indian J Ophthalmol. 2018;66(1):36-38.
12. Forton FMN. The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea?.
49 Dermatol Ther (Heidelb). 2020;10(6):1229-1253
13. Wesolowska M, Knysz B, Reich A, et al. Prevalence of Demodex spp. in eyelash follicles in different populations. Arch Med Sci. 2014;10(2):319-324.
14. Abah ER, Oladigbolu KK, Rafindadi AL, Audu O. Eyelash extension use among female students in a Tertiary Institution in Nigeria: A study of kaduna polytechnic, Kaduna. Niger J Clin Pract. 2017;20(12):1639-1643.
15. Amano Y, Sugimoto Y, Sugita M. Ocular disorders due to eyelash extensions. Cornea. 2012 Feb;31(2):121-5.
16. p-Cymene and organic peroxides as indicators of oxidation in tea tree oil. A report for the Rural Industries Research and Development Corporation by Ian Southwell, 2006.
17. Rutherford T, Nixon R, Tam M, Tate B. Allergy to tea tree oil: retrospective review of 41 cases with positive patch tests over 4.5 years. Australas J Dermatol. 2007;48(2):83-7.
18. Koo H, Kim TH, Kim KW, Wee SW, Chun YS, Kim JC. Ocular Surface Discomfort and Demodex: Effect of Tea Tree Oil Eyelid Scrub in Demodex Blepharitis. J Korean Med Sci. 2012 Dec;27(12):1574-1579.
19. Studdiford J, Stonehouse A. Allergic Contact Dermatitis from Tea Tree Oil (Melaleuca alternifolia) National Institutes of Health, Department of Family & Community. Medicine. Faculty Papers. Paper 12. 2007
20. Maher TN. The use of tea tree oil in treating blepharitis and meibomian gland dysfunction. Oman J Ophthalmol. 2018;11(1):11-15.
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