60 SKIN MICROBIOME Screen exposure time was compared
between the 2 groups thanks to a daily logbook filled by all the volunteers, making sure that digital stress exposure time was not significantly different during the study, either during the day, or more specifically during the evening. No significant differences were detected with an average of 4.5 hours daily exposure for the placebo group versus 5.1 hours for Gardenia fruit extract, and respectively 2.6 hours versus 2.4 hours in the evening, validating the possibility to compare the groups. The anti-ageing efficacy of Gardenia fruit
extract was analysed by the quantification of crow’s feet wrinkles number using VISIA® analysis at D0, D28 and 56. As confirmed by the visual observation of volunteers pictures, Gardenia fruit extract at 2% induces a significant reduction of crow’s feet wrinkles number, down to -21% versus placebo (-26% versus D0). Panellists were asked to assess both
products efficacy on their skin quality after 56 days of use. Significant differences were noticed in terms of skin hydration and smoothness. The wellbeing benefits of Gardenia fruit
extract were also studied by analysing daily logbooks of the volunteers during 56 days. The logbook was filled by the volunteers every day in order to collect data about different parameters, such as: source of exposure to digital stress, screen exposure duration, easiness to fall asleep, number of nocturnal awakenings… Gardenia fruit extract at 2% has a
significant impact on the sleep quality versus placebo, according to the perception of volunteers. It makes it easier to fall asleep (it was easy to fall asleep 90.6% of the nights versus 84.8% of the nights only with the placebo), and drastically decreasing the number of awakenings every night (20.0 nights without awakenings over 28 versus only
Easiness to fall asleep (28 nights) *** **
100% 80% 60% 40% 20% 0%
84.8% 9.4% 2.3% 28 8.0% 21 84.8% 90.6% 97.7% 14 14.3% 7 Placebo
SynchronightTM 2%
n Hard to fall asleep n Easy to fall asleep
SynchronightTM 2%
(focus on 18-35 y.o)
0 Placebo 20.0%
SynchronightTM 2%
21.8%
SynchronightTM 2%
n I woke up last night n I did not wake up last night
(focus on 18-35 y.o)
13.7% 6.2% 15 -87%* 10 5 3.0% 0 Placebo
SynchronightTM 2%
SynchronightTM 2%
(focus on 18-35 y.o)
4.0% 23.0% -83%* *** 20 D28 0% D56
-5%
-10%
-15%
-21%* -20% -25% ** -30% n Placebo n SynchronightTM Figure 6: Reduction of crow’s feet wrinkles student’s t-test: * p<0.05, ** p<0.01.
14.3 for the placebo). The median number of awakenings during 28 nights was drastically reduced as well, with only 3.0 awakenings in average versus 23.0 for the placebo. A focus was made more precisely on the
youngest part of the panel (18 to 35 years old). It is noticeable that the activity of Gardenia fruit extract on the wellbeing is even stronger on this younger population, with a drastic improvement of the easiness to fall asleep, for more than 97% of the volunteers, and of the nights without awakenings (close to 22 nights without awakenings over a period of 28 nights).
Conclusion Gardenia fruit extract and therefore
Average number of nights without awakenings (28 nights)
***
Synchronight™ are set to become key elements of beauty well-being by providing an answer to all consumers who are sleep- deprived and looking for youthful and glowing skin.
PC
References 1 Alexandra P, et al. Natural Deep Eutectic
Solvents – Solvents for the 21st Century. ACS sustainable Chem. Eng 2014; 2: (5):1063-1071.
2 Yuntao et al. Tailoring properties of natural deep eutectic solvents with water to facilitate their applications. Food Chemistry 2015; 187:14-19.
3 Choi et al. Are Natural Deep Eutectic Solvents the Missing link in understanding cellular metabolism and physiology 2011; 156:1701- 1705.
Median number of awakenings (28 nights) 2%
Figure 7:Wellbeing improvement of sleep quality ***p<0.001, **p<0.01 dichotomic analysis with Fisher test *p<0.05, #p<0.1 non parametric analysis with Mann Whitney test.
PERSONAL CARE ASIA PACIFIC November 2020
∆D0DX wrinkles number (%)
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