DEODORANTS 69
n Placebo cream n Cream with 1% DEOBIOME NONI PRCF **
2.5 -30%
40 20 0
-20 -40 -60 -80
-100
1.5 Initial 3 days + 24h Figure 5: Clinical evaluation of odour intensity reduction. -34% -43% -51% -52% -63% -100% n Placebo cream n Cream with 1% DEOBIOME NONI PRCF Figure 4: Clinical evaluation of odorous volatile molecules reduction.
Armpit molecular analysis First, more than 100 molecules responsible for body odour were analysed by gas chromatography, and demonstrated the reduction of these odorous molecules by 39%. The graph in Figure 4 clearly shows a decrease in these compounds after the application of the active vs placebo.
Armpit odour intensity On the other hand, the average intensity of underarm odour was studied in the 19 volunteers after having applied the active. The study showed a 30% reduction versus initial treatment and down to 82% (Fig 5).
** p<0.01 3 ** -67% n Placebo cream n Cream with 1% DEOBIOME NONI PRCF -39%
800 700 600 500 400 300 200 100 0
Initial
In vivo 2: Evaluation of axillary perspiration rate In a second in vivo assay, the rate of axillary perspiration was evaluated in a panel of 8 volunteers, women and men, between 28 and 62 years old, who applied a placebo cream and another cream with a dose of 1% of the active ingredient. The active was shown not to significantly alter natural armpit perspiration (Fig 6).
In vivo 3: Evaluation of feet odour intensity modulation And finally, in a third in vivo test made up of a group of 10 volunteers (23-57-years old), the average intensity of foot odour was evaluated. It was shown that with a
n Placebo cream n Cream with 1% DEOBIOME NONI PRCF
3 days + 24h Figure 6: Clinical evaluation of axillary perspiration rate.
cream that contained 1% of the active, a 21% average reduction of foot odour intensity versus initial measurement and down to 47% was possible (Fig 7).
Conclusion The active ingredient Deobiome Noni is an innovative deodorant treatment that respects the skin and its microbiota. When it comes to talk about the main
concepts around this active, this would lead us to the following claims: protection and balance of the microbiome, clean beauty, skin health and detoxification, microbial load control, odour fingerprint modulation, bacterial and fungal dysbiosis prevention, and let your skin breathe. The treatment allows the armpit to
breathe while avoiding the generation of bad odour, allowing the skin to breathe, and respecting the biological ecosystem. Regarding the different applications in the
-21%
cosmetic sector, the active ingredient has a wide range of applications in the field of reducing body, axillary, foot, and scalp odour, and rebalancing the microbiota. Made from stem cells of the plant Morinda
citrifolia,Deobiome Noni represents a scientific advance for the treatment of body odour, respecting the skin microbiota, thanks to the innovative mechanism of action of the active ingredient, being the first biological deodorant in the market.
PC 2 Initial Figure 7: Clinical evaluation of feet odour reduction. August 2020 3 days + 24h
References 1
https://www.beautyindependent.com/trends-
natural-deodorant-market-growth/
2
https://www.grandviewresearch.com/industry- analysis/organic-deodorant-market
PERSONAL CARE GLOBAL
Odour intensity
% of variation vs untreated
Difference in sweat weight (mg)
Odour intensity
Alcohols Aldehydes Aromatic alcohols Lactones Organic acids
Terpenes
Oxygen-containing compounds Sulfur-containing compounds
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