SKIN CARE 21


Rayon/polyester compound


Hexylglycerin Cyclohexylgly.*


Phenoxy Et Me-Paraben


CapGly ** EHG


0


* Cyclohexlglycerin ** Caprylyl Glycol


Figure 10: Adsorption rate for non-wovens.


a result it is confirmed that cyclohexylglycerin 1% with keratin has the same effect as benzyl alcohol. Relying on the above results and using cyclohexylglycerin as an alternative to benzyl alcohol, safer hair cosmetics can be produced.


Irritation performance test The following tissue viability test underlines the lower irritation of hexylglycerin. Reconstructed human cultured epidermal model was used (LabCyte EPI-MODEL, Japan Tissue Engineering Co., Ltd). The tissues were exposed to the test


materials and incubated with the assay medium for 24 hrs. (37°C, 5% CO2


). The


tissues were then transferred to MTT medium and incubated for 3 hrs. (37°C, 5% CO2). After incubation, the tissues were extracted with isopropanol (IPA) and absorbance was measured. The tissues treated by hexylglycerin keep higher tissue viability than existing glycols. Therefore, it is expected that skin irritation is lower.


Adsorption into fabrics and face masks Another positive feature of both hexylglycerin and cyclohexylglycerin is that they both have lower adsorption into various fabrics than e.g. phenoxy ethanol, methyl paraben, caprylyl glycol and ethylhexylglycerin. Hence, hexylglycerin and cyclohexylglycerin can easily stay in any wet wipe solution while still maintaining an adequate antimicrobial effect at low concentration. Figure 10 shows the advantage in the wet wipe applications . The test was conducted as follows:


A non-woven fabric was soaked in each test solution (3 times the amount of the fabric). After 2 weeks, squeezed solutions were analysed by gas chromatography,


August 2020 n Isopropyl myristate n Triethylhexanoin Hexylglycerin Canrylyl glycol 20 40 60 80 100 0 20 40 60 80 100 0 20 40 60 Adsorption rate for each fabric after 2 weeks (%) 80 100 Pulp Cotton


Phenoxyethanol Ethylhexlglycerin


Methylparaben 0 20 40 60 Residual ratio in water phase (%) Figure 11: Residual ratio in water phase.


leading to the results that both hexylglycerin and cyclohexylglycerin are less adsorbed into non-woven fabrics than parabens and conventional glycols. As they are more likely to stay in solutions, they are useful preservative boosters for various types of non-woven fabric products (e.g. wet wipes and face masks). The face mask market is expanding year by year both in Asia and Europe. Two methods were conducted to challenge the application in face masks. The first method evaluated face masks with non-woven fabrics while the second method evaluated only the solution. After two weeks it was found that phenoxyethanol is only effective against mould in the pure solution, while mould increased in the solution with non-woven fabric. Hexylglycerin on the other hand, was


effective in both solution and the product form with non-woven fabrics.


Study in emulsion system Hexylglycerin also has positive attributes in terms of combination with oily ingredients. One of the reasons for the better combination is that it stays in the water phase and has a high water solubility. Therefore, it makes the preservation designs of emulsion systems a lot easier. Figure 11 examines the Water-Oil partition rate. 3 mL of water and oil were weight and 3 mg of the sample were added. After shaking the combinations, it is quantified by gas chromatography. In contrast to parabens and phenoxyethanol, hexylglycerin is not affected by oily ingredients. Compared to conventional preservatives, hexylglycerin and


PERSONAL CARE GLOBAL 80 100


Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36  |  Page 37  |  Page 38  |  Page 39  |  Page 40  |  Page 41  |  Page 42  |  Page 43  |  Page 44  |  Page 45  |  Page 46  |  Page 47  |  Page 48  |  Page 49  |  Page 50  |  Page 51  |  Page 52  |  Page 53  |  Page 54  |  Page 55  |  Page 56  |  Page 57  |  Page 58  |  Page 59  |  Page 60  |  Page 61  |  Page 62  |  Page 63  |  Page 64  |  Page 65  |  Page 66  |  Page 67  |  Page 68  |  Page 69  |  Page 70  |  Page 71  |  Page 72  |  Page 73  |  Page 74  |  Page 75  |  Page 76  |  Page 77  |  Page 78  |  Page 79  |  Page 80  |  Page 81  |  Page 82  |  Page 83  |  Page 84