DEODORANTS 67
Pro-microbiota deodorant for axilla perspiration
n Ò. Expósito, A. Guirado, D. Robustillo, R. Vallecillo, A. Gallego, M. Mas, P. Riera, S. Ruiz, D. Luna, S. Laplana, T. Ruiz - Vytrus Biotech, Spain
The flourishing clean movement is one of the new consumer trends with people searching and choosing products based on natural and sustainable ingredients. This movement is also visible in the cosmetic sector. In the deodorant market, there is a need
for alternatives to the conventional products. New products that can be respectful to the skin and its important physiological functions such as sweat production, as well as with the skin microbiota. According to research firm Mintel,1
one-
fifth of deodorants and antiperspirants users consider aluminium-free formulas to be important in their purchase decisions. Likewise, this market analysis highlights that US sales of natural deodorants increased by 12% in 2019, while their conventional counterparts decreased their sales by 2% approximately. The global size of the organic deodorant
market was valued at $62.9 million in 2018 and is expected to be expanded in a 14.1% CAGR (Compound Annual Growth Rate) from 2019 to 2025. According to this study carried out by Grand View Research,2
it is
hardly surprising that the research and new developments of deodorants blend into the lifestyle preferences behind the current consumers. Human beings have been developing
personal hygiene habits that sweep the skin ecosystem and obstruct the natural function of the armpit.
The daily battle against body odour is
still dominated by two classical strategies: deodorants and antiperspirants. The so- called deodorants often focus on eliminating bacteria by applying alcohol bases, bactericidal actives or cover malodour by using perfume. On the other hand, traditional antiperspirants’ strategies are based on clogging the pores with derivates of aluminium salts (Aluminium Chlorohydrate), thereby depriving the bacteria in the axilla of malodour precursors and water. In addition, antiperspirants are often antimicrobials which can cause armpit irritation and create a feeling of dryness in the skin. Vytrus Biotech has broadened the
scope of axillary care by designing a biological deodorant ingredient that effectively eliminates the bad odour. The strategy is an innovative combination that
addresses the care of the microbiota through two key channels: using a new prebiotic technology, and the microbiota re-balancing through the interaction with bacterial communication (Quorum Quenching).
The first biological deodorant The new active ingredient discussed in the article (INCI name: Morinda Citrifolia Callus Culture Lysate) combines an innovative use of prebiotics and the latest in plant stem cell technology in the field of microbiota: Quorum Quenching (Fig 1). The active ingredient follows two
strategies which act synergistically against the formation of malodorous molecules derived from the armpit commensal microbiota:
A biological strategy Morinda citrifolia, known as Noni plant, is a native plant from Southeast Asia (Indonesia) and Australia. It is used worldwide for its properties: antitumor, anthelminthic, analgesic, anti- inflammatory, immuno-stimulant, several skin diseases, urinary tract disorders, fever, diabetes, etc. The concentrated metabolome of the
Figure 1:Mechanism of action of Deobiome Noni. August 2020
plant stem cells from Morinda citrifolia is rich in specific fractions of terpenes. This molecular cocktail is designed to efficiently interfere with different bacterial species and prevent the exponential growth of certain species that would cause an
PERSONAL CARE GLOBAL Abstract
Body odour modulation has historically been a concern for human beings and studying the microbiota involved represents an approach which this topic may naturally be viewed from. The new active Deobiome Noni (INCI: Morinda Citrifolia Callus Culture Lysate) is an active ingredient made from Morinda citrifolia plant stem cells that introduces the concept of a biological deodorant. By combining an innovative prebiotic technology and the latest advances in plant stem cell technology in skin microbiota treatment, it has been demonstrated how to modulate body malodour while being respectful to the skin microbiota and its ecosystem. The mechanism of action of the active has been evaluated by performing several in vitro and in vivo tests to demonstrate the effective body odour reduction while allowing the natural axillary perspiration.
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