HYGIENE Safety for final users is another fundamental
factor, as the product is supposed to be applied on the skin many times each day. Regardless of whether the product is a cosmetic or a biocidal product, it is important to guarantee safety of use when applied following the directions indicated on the label. Finally, quality cannot be underestimated in terms of offering a nice texture for a pleasant product experience, for example trying to reduce long absorption time, sticky after-feel or residues after drying out. Quality control points include many
physical-chemical parameters, such as pH, viscosity, turbidity, volatile content, density and active content (through HPLC analysis for the quantitative evaluation of alcohol in the bulk). In particular, these two last parameters will confirm the alcohol content, guaranteeing antimicrobial activity.
Safety in manufacturing Formulating with alcohols involves handling very flammable raw materials and finished products. Consequently, this includes a risk of explosions, not only in the facilities where the raw materials are stored and the product is manufactured, but also where the finished products in the final pack are being stored. Therefore, it is mandatory to define and
operate in specifically designed ATEX areas for explosive atmospheres and to take into account all the possible control measures. These include isolating all potential ignition sources, manufacturing and handling bulk in ATEX-
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manufacture and distribute safe, efficacious and pleasant hand sanitisers. Although these are not technically complex
formulations, many different aspects had to be taken into consideration and several challenges had to be solved along the way, to deliver hand sanitisers guaranteeing quality, safety and efficacy to the final users.
Acknowledgements Special thanks to Ainara Dieguez, Miguel Ayora and Fernanda Motta for the precious information and their valuable support.
certified reactors, equipment and accessories. All the operators involved in the
manufacturing and filling process have to use antistatic garments. The facilities must be equipped with detectors for potential explosive gases and powders, and ventilation systems for gases and flammable powders. Finally, procedures for risk assessment and prevention of explosions must be defined and in place, readily available upon request and for any operator.
Conclusion During the COVID-19 global health emergency, Laboratorios Maverick quickly reacted to help produce hand sanitising products for health professionals and general consumers. This involved a rapid, intense and coordinated work between all departments to design, test,
PC
References 1. WHO Guidelines on Hand Hygiene in Health Care, World Health Organisation 2009
2. Guide to Local Production: WHO- recommended Handrub Formulations, World Health Organisation Revised April 2010
3. Fares H. Overview of US sanitiser regulations and formulas. Personal Care, July 2021
4. Perry M. Regulation of hand sanitisers in the EU and US. Personal Care, January 2021
5. Guidance on the applicable legislation for leave-on hand cleaners and hand disinfectants (gel, solution, etc.), European Commission
6. Technical Document on the Scope of Application of the Cosmetics Regulation (EC) No 1223/2009 (Article 2(1)(A)) - Product claims of leave-on hydro alcoholic hand gels in the context of COVID-19 pandemic - Agreed by the Sub-Working Group on Borderline Products, 12 November 2020
www.personalcaremagazine.com
March 2022 PERSONAL CARE
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