54 MARINE INGREDIENTS
great suitor for over 270 different cosmetic formulations. In addition, it is suggested that EPS has
a potential advantage to be used as a bio- lubricant and was found to be superior to the most widely used hydrogel lubricant on the market – hyaluronic acid. When compared to hyaluronic acid, the polysaccharide showed better results in friction and wear measurements and presented better lubricity at higher loads and higher temperatures.12 The polysaccharide secreted from
Porphyridium cruentum is a uniquely strong anti-inflammatory13
Several studies reported that EPS inhibited the enzyme hyaluronidase, an action that is known to mediate inflammation and tumor metastasis.14
When the EPS was tested for its as well as anti-viral agent. Furthermore, EPS from P. cruentum
enhanced the production of Tumor Necrosis Factor Alpha (TNF-α) cytokine and Interleukin – 6 (IL-6).15
anti-viral activity, it was found eliminate Herpes simplex, Hepatitis B, Influenza, HIV and many other viruses.16-22 “Each cell of a certain microalgae is like a
miniature plant or factory,“ explains Amikam Bar-Gil, CTO and Co-Founder of Yemoja. “It requires certain inputs for it to create the desired products. Some of these inputs are environmental factors that can induce a specific amount of stress on the micro-algae’s cell, guiding it to synthesise its defences according to the stressor. Stressors can come in various forms including high light intensity, UV radiation, sudden change in temperature/salinity/nutrient concentration, and more. In this case the highly- desired EPS is produced via the control of these stress factors. The closed-system bioreactor is the ideal way to achieve cultivation precision.”
In-house high precision marine algae cultivation will boost quality and scalability Yemoja’s in-house proprietary cultivation system is compiled of rows of vertical columns that are compartmentalised and isolated from the adjacent columns. Depending on the type
PERSONAL CARE April 2021
of microalgae and the state it is in, different properties may be observed. There are also certain columns specially designed to allow the insertion of light sensors as well as pH probes. Monitoring software was specifically designed to ensure consistent accuracy in its cultivation systems. It records all data critical to enabling further automatisations, and maintains input of AI factors from batch to batch of algae grown reconciling observed versus expected parameters were in order to make the necessary adjustments. The software also provides the potential for overseeing and regulating the growth of algae from afar. This will provide ease of access when it comes to future plants and multi-site monitoring and control. Within the software, a history of each batch is saved and can be referenced as needed to compare potentially different inputs of ingredients or growth parameters. In essence, Yemoja’s super-intensive
cultivation methodology maintains absolute control of key parameters such as temperature, pH, light, and CO2
emissions, overcoming
many of the industry’s hurdles, specifically compositional homogeneity, scalability, and contamination proofing, ensuring clean and safe microalgae throughout the process. Bar-Gil grants a zoom into technological
systems that lie within the walls of Yemoja’s, state-of-the-art facility and that work in concert to garner optimum desired results. A highly- engineered bubbling system allows for control of the strength and speed of the gaseous intake for each column and where pH is monitored and adjusted. Different strains prove to thrive in different bubbling conditions, with certain strains showing an affinity towards stronger and faster flow, while others prefer a gentler aeration.
An LED lighting system controls the
desired type and strength of light that the algae in each column will receive. The specific spectrum of light and intensity, applied will result in the production of different pigments and compounds by the micro-algae. Its highly developed LED technology provides more
efficient lighting without excessive heat- generation, hence reducing the strain on the cooling system.
A green factory to grow algae sustainably A time-controlled fertiliser system is used to provide nutrition for the algae or to chemically change certain environmental factors that affect their growth. These nutrients can lead the micro-algae to a stabilised state, a growth state, or to a deficient state. “For obvious reasons, it is crucial to have control of which state the algae are in,” explains Erez Ashkenazi CEO and co-founder at Yemoja. ”If the algae are found to be in a nutrient deficient state during an early stage, this will have direct impact of the culture density and the amount of biomass that can be extracted at later stages. On the other hand, given the right timing, the prevention of certain elements can induce processes within the cell that will result in powerful compounds to be produced via the cell’s own defence mechanisms.” As the algae proceeds to visibly develop in
the columns over time, Yemoja’s microscope camera can give real-time feedback of the purity and density of the growing cultures, ensuring they are clean of unwanted contaminants. Close monitoring of its growth and recording the data has enabled the company to predict the time frame to get to a specific culture density and has been instrumental in helping the company reach optimum results at a faster pace. “The world is gravitating towards natural
components. The cosmetic and nutraceutical industries are increasing their demand for these substances due to their potential for the human body. Our process for growing algae is green and eco-friendly,” says Ashkenazi. “If suitable, the media used for cultivation is recycled for future batches, and if it is not suitable, it is repurposed for cleaning the system. All the strains of algae are wild-types, non-GMO and are monitored around the clock to ensure no genetic drifts
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