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MARINE INGREDIENTS 87


Hair youthfulness is improved. This natural active is patented, COSMOS


approved and can be used in China. It is suitable in numerous daily hair care products, in particular hair tonic, hair restorer, conditioner, balancing serums, treatment or styling gels as well as in sensitive scalp care formulations. Caphira®


n Placebo n Active 2%


exclusively distributed in the USA by Biosil Technologies Inc.


References 1 Elston DM. Commentary: Iron deficiency and hair loss: Problems with measurement of iron. J. Am. Acad. Dermatol. 2010; 63: 1077-82.


2 Fatemi Naieni F, Ebrahimi B, Vakilian HR, Shahmoradi Z - Serum iron, zinc, and copper concentration in premature graying of hair. Biol. Trace Elem. Res. 2012.146: 30-4.


3 Rushton DH, Ramsay ID, James KC, Norris MJ, Gilkes JJ - Biochemical and trichological characterization of diffuse alopecia in women. Br. J. Dermatol. 1990.123: 187-97.


4 Millar SE - Molecular mechanisms regulating hair follicle development. J. Invest. Dermatol. 2002.118: 216–25.


5 Schneider MR, Schmidt-Ullrich R, Paus R - The hair follicle as a dynamic mini organ. Curr. Biol.2009.19: R132–142.


6 Kulessa H, G. Turk, Hogan BL - Inhibition of BMP signaling affects growth and


is the trade name of this active, PC


-72 -74 -76 -78 -80 -82 -84


0 -5 -76 6% -82 Figure 8: Decrease of the erythema score.


differentiation in the anagen hair follicle. EMBO J. 2000. 19: 6664–6674.


7 Kingston K L Mak, Siu Yuen Chan - Epidermal Growth Factor as a Biologic Switch in Hair Growth Cycle – J. Biol. Chem. 2003. 278 (28): 26120-26126.


8 Trüeb RM - Further Clinical Evidence for the Effect of IGF-1 on Hair Growth and Alopecia - Skin Appendage Disord. 2018.4: 90–95.


9 Reichrath J, Schilli M, Kerber A, Bahmer, F A et al. - Hair follicle expression of 1,25- dihydroxyvitamin D3 receptors during the murine hair cycle. Br. J. Dermatol. 1994. 131: 477–482.


10 Sakai Y, Kishimoto J, Demay MB - Metabolic and cellular analysis of alopecia in vitamin D receptor knockout mice. J. Clin. Invest. 2001.107: 961–966.


-10 -15 -20 -25 -30


-9.5 17% -27.3 Figure 9: Decrease of the inflammation score.


11 Saini V, Zhao H, Petit ET, Gori F, Demay MB - Absence of vitamin D receptor (VDR)-mediated PPARg suppression causes alopecia in VDR-null mice- FASEB J. 2017. 31: 1059–1066.


12 Demay MB, MacDonald PN, Skorija K, Dowd DR et al.- J. Steroid Biochem. Mol. Biol. 2007. 103 (3-5): 344-346.


13 Petiot A, Conti FJ, Grose R, Revest JM et al. - A crucial role for Fgfr2-IIIb signaling in epidermal development and hair follicle patterning. Development. 2003.130: 5493–5501.


14 Schmidt-Ullrich R, Paus R- Molecular principles of hair follicle induction and morphogenesis. Bioassays. 2005.27: 247–261.


15 Fujimoto A, Nishida N, Kimura R, Miyagawa T et al. - FGFR2 is associated with hair thickness- in Asian populations- J. Human Gen. 2009. 54: 461–465.


n Placebo n Active 2%


Beautiful value creation for tomorrow Senscalm


Peach blossom tears for sensitive scalp INCI name : Prunus Persica (Peach) Gum


Whitenergy


Star Flower from JEJU Island - Dual Effect Skin Lightener INCI name : Stellaria Media (Chickweed) Extract


Ecomushlyte


Maintain The Skin Homeostasis For Healthy-Looking Skin INCI name : Ganoderma Lucidum(Mushroom) Stem Extract / Grifola Frondosa Fruiting Body Extract / Lentinus Edodes Mycelium Extract


Bio Honey Acid


Gentle Exfoliation For Glowing Skin INCI name : Honey Extract


QS Control AC


ACNE Care by Anti-Quorum Sensing Strategy INCI name : Lactobacillus ferment & Pinus Densiflora Leaf Extract


Natural Skin Natural Life the botanical beauty story...


May 2020


231 Munmakgongdan-gil Munmak-eup Wonju-si Gangwon-do 26362 Rep. of Korea TEL. +82-33-732-7561 FAX. +82-33-732-7563 e-mail. info@dermalab.co.kr


PERSONAL CARE NORTH AMERICA


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