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HYGIENE


Hacking maskne: A plant stem cell story


O. Expósito, A. Guirado, D. Robustillo, R. Vallecillo, A. Gallego, M. Mas, P. Riera, D. Luna, S. Laplana, T. Ruiz, S. Ruiz, M. Gibert - Vytrus Biotech, Spain


Consumer trends throughout 2020 have been shaken by the global pandemic we are experiencing. This health crisis has marked a milestone in consumer behaviour patterns, and cosmetics is no exception. Currently, due to the use of protective


elements such as masks, as well as other related factors, the appearance of acne has increased among the population, no matter the age. The constant friction of the mask fabric on our skin, together with the lack of perspiration, has led to the phenomenon known as ‘maskne’. A more technical term is mechanical acne, and it is also known as ‘athlete’s acne’ or ‘friction’ because it is the result of the mechanical friction of a tissue against the skin and is common in athletes. “‘Actually, it is a common acne that can


occur in people who never had it. The mask will be essential to protect ourselves and we have to live with it. However, our skin is not used to it and this is one of its effects,” said Dr. Mar Mira to BBC World magazine, specialist in aesthetic medicine and nutrition and co-founder of the Mira + Cueto clinic, in Madrid, Spain. Maskne is something more usual in health


professionals as stated in an investigation published by Journal of the American Academy. It said that at least 83% of health professionals in Hubei (China) got dermatological diseases on their face as a result of mask wearing. Amy Kassouf – dermatologist at Cleveland


Clinic (Ohio), said that the acne derived from mask wearing “…has always been a problem in health professionals who are obligated to use them. Now that its use has been spreaded to the public is when the problem has raised”. When either talking or breathing, the mask tends to trap a lot of hot air, which in addition to being annoying, creates an ideal environment for the growth of bacteria and skin mites.


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The friction of the mask accentuates acne breakouts, according to a report from the Cleveland Clinic. Oily or acne-prone skin is not new but one


of the biggest concerns in skin care together with an obligation that seems to have come to stay, such as the use of a mask, lead us to consider new strategies to deal with acne from a more natural way. Vytrus Biotech proposes a new treatment based on plant stem cells, respectful to the skin microbiota, which acts on skin conditions caused by mask wearing such as acne.


Blocking the microbial communication The active ingredient Quora Noni™ (INCI: Morinda Citrifolia Callus Culture Lysate) is the concentrated metabolome from Noni totipotent cells. This


Plant Anti-Quormones OH OHO


O CH3 OH H3 CH3 H3 Figure 1: Mechanism of action (Quorum Quenching). www.personalcaremagazine.com May 2021 PERSONAL CARE C C CH2 CH2 CH3


ingredient acts as a treatment and prevention of acne-prone skin, being a great sebum-regulator and improving skin imperfections


What is the origin of acne? Quorum Sensing (QS) is a bacterial coordination system. Bacteria use QS to carry out coordinated behaviours such as antibiotic generation, biofilm generation or bioluminescence. Environmental changes such as excess of sebum or pore-clogging in acne-prone skin cause microbial dysbiosis (microbiome imbalance). The bacterial dysbiosis promote the activation of QS and consequently the development of coordinated behavours of certain bacterial species in the pore. Through QS, species such as C. acnes or S. aureus can coordinate the generation of biofilm or virulence factors that activate the


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