COVER STORY: LIPOID KOSMETIK ADVERTISEMENT FEATURE
lipophilic actives are significantly increased by PhytoSolve® at a skin depth between 0 and 680 µm. In comparison to the control groups without phospholipids, the PhytoSolve® technology significantly elevated the amounts of actives by 413 % (retinyl palmitate) and 315 % (coenzyme Q10), respectively (Figures 3 and 4).
Conclusion PhytoSolve® is a unique technology that provides a synergistic complex between natural phospholipids and attractive cosmetic actives. PhytoSolve® products ensure effortless processing into cosmetic formulations, effective and safe skin penetration and an improved potency of the actives.
References 1. Kim B, Cho HE et al. Transdermal delivery systems in cosmetics. Biomedical Dermatology. 2020; 4, 1 – 12
2. Van Hoogevest P, Fahr A. Phospholipids in cosmetic carriers. Nanocosmetics: From Ideas to Products. 2019; 95 – 140
3. Knox S, O’Boyle NM. Skin lipids in health and disease: a review. Chemistry and Physics of Lipids. 2021; 236, 105055
4. Kirjavainen M, Mönkkönen J et al. Phospholipids affect stratum corneum lipid bilayer fluidity and drug partitioning into the bilayers. Journal of Controlled Release. 1999; 58, 207 – 214
A 1.5 B 6.0
7 Control ■ PhytoSolve® A■
* 1.0 4.0
0.5
2.0
0.0 PC Depth Skin SC 0-10µm EP 10-80µm DR 80-280µm 280-480µm 480-680µm
Figure 3: PhytoSolve® A increased the amount of penetrated retinyl palmitate. (A) shows an overview of penetrated retinyl palmitate per diffusion area (µg/cm2
A 0.8 0.6 2.0 B ) in all analyzed skin sections. (B)
summarizes the penetrated amount of retinyl palmitate in a skin depth up to 680 µm. N = 3; Mean ± SEM = Student’s t-test Control vs. PhytoSolve® A, * = p < 0.05
Control ■ PhytoSolve® Q10 ■
0.0 Control PhytoSolve® A
0.4 1.0 0.2
0.0
Lipoid Kosmetik AG Sennweidstrasse 44/46 6312 Steinhausen Switzerland Phone: +41 41 748 33 33 Email:
info@lipoid-kosmetik.com
Depth Skin SC 0-10µm EP 10-80µm DR 80-280µm 280-480µm 480-680µm
Figure 4: PhytoSolve® Q10 increased the amount of penetrated coenzyme Q10. (A) shows an overview of penetrated coenzyme Q10 per diffusion area (µg/cm2
) in all analyzed skin sections. (B) summarizes the penetrated amount of coenzyme Q10 in a skin depth up to 680 µm. N = 3; Mean ± SEM
TABLE 1: PHYTOSOLVE® PRODUCTS AND THEIR CHARACTERISTICS PhytoSolve® Q10
PhytoSolve® A Skin energizer
■ Improvement of skin vitality ■ Reduction of fine lines
INCI: Glycerin, Aqua (Water), Ubiquinone, Caprylic/ Capric Triglyceride, Lecithin, Tocopherol, Sodium Hydroxide
Anti-aging hero
■ Stimulation of cell renewal ■ Reduction of wrinkle depth
INCI: Glycerin, Aqua (Water), Retinyl Palmitate, Caprylic/Capric Triglyceride, Lecithin, Tocopherol
PhytoSolve® E Antioxidant shield
■ Protection of skinfrom environmental stress
■ Skin repair
INCI: Glycerin, Tocopheryl Acetate, Caprylic/Capric Triglyceride, Aqua (Water), Lecithin, Tocopherol
PhytoSolve® Astaxanthin
Marine power booster ■ Skin repair & protection ■ Reduction of wrinkles ■ Skin tone improvement
INCI: Glycerin, Aqua (Water), Caprylic/Capric Triglyceride, Lecithin, Haematococcus Pluvialis Extract, Tocopherol, Sodium Chloride, Sodium Hydroxide, Helianthus Annuus (Sunflower) Seed Oil
0.0 Control
PhytoSolve® Q10
www.personalcaremagazine.com
June 2025 PERSONAL CARE
Amount of Active (µg)
Amount of Active (µg)
Amount of Active 0-680 µm (µg)
Amount of Active 0-680 µm (µg)
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