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BEAUTY FROM WITHIN


specific bacteria.18 The regular consumption of prebiotic-rich


foods improves the gut environment, which aids in the prevention of chronic inflammation in the body.19 Postbiotics, the metabolic byproducts of


probiotics, have been shown to stimulate the immune system and modulate inflammation. When pre- and probiotics are consumed, they can reduce systemic inflammation markers and oxidative stress. Oral consumption of postbiotics can help


maintain a healthy balance of gut bacteria and strengthen the skin’s protective barrier. They provide antioxidant benefits and block enzymes that break down skin structure. Because of this, postbiotics may also enhance UV protection and slow skin ageing.20 One of the primary influencers of microbial


composition is diet. A typical Western diet, high in processed foods, fat, and sugar but low in fibre, can reduce the variety of gut bacteria and promote inflammation by increasing certain harmful bacteria such as Bacteroidetes and Biliophiles. Common food additives like Polysorbate


80 and carboxymethylcellulose may further upset gut balance, leading to inflammation that can damage tissues. Additionally, maltodextrin, a type of carbohydrate, has been shown to stress intestinal cells, reduce mucus production, and increase inflammation in mice studies.21 A fibre-rich diet can promote the growth


of beneficial bacteria, producing SCFAs that are beneficial for gut health. To prevent dysbiosis in the intestinal microbiota, making better dietary choices and lifestyle changes associated with better gut microbiota diversity and function outcomes is essential.


Skin care formulations targeting the microbiome In addition to diet and pre- and probiotic supplements, cosmetic brands have been creating microbiome-targeting products to balance the skin microbiome. These microbiome-friendly products often contain ingredients like fermented extracts and probiotic-infused formulations. Fermented extracts are rich in bioactive


compounds that can enhance skin hydration and elasticity. Probiotic-infused formulations introduce beneficial bacteria directly to the skin, helping to balance the skin microbiome and improve conditions such as acne and rosacea. By preserving and enhancing the skin natural microbiota, microbiome-friendly topicals promote healthier skin and reduce the risk of irritation and inflammation.


Conclusion With a fast-paced lifestyle within Western culture, consumers are beginning to demand more natural products. When formulating future cosmetic products, it is essential to develop solutions that support the balance between the host and microbiome, fostering a more harmonious and natural relationship. Novel topical formulations respectful of the skin microbiome paired with supplements


www.personalcaremagazine.com


23


Camargo CA Jr, Hasegawa K, Bordenstein SR. Human microbiome variation associated with race and ethnicity emerges as early as 3 months of age. PLoS Biology. 2023; 21(8)


8. Siddiqui R, Makhlouf Z, Khan NA. The increasing importance of the gut microbiome in acne vulgaris. Folia Microbiol (Praha). 2022 Dec;67(6):825–35


9. Sung M, Choi Y, Park H, Huh CS. Gut Microbiome Characteristics in Mothers and Infants According to the Presence of Atopic Dermatitis. Biomed Res Int. 2022 Apr 23;2022:8145462


10. Stojanov S, Berlec A, Štrukelj B. The Influence of Probiotics on the Firmicutes/ Bacteroidetes Ratio in the Treatment of Obesity and Inflammatory Bowel disease. Microorganisms. 2020; Nov 1;8(11):1715


11. Nestle F, Kaplan D, Barker J. Mechanisms of Disease: Psoriasis. N. Engl. J. Med. 2009, 361, 496–509


12. Buhaș MC, Gavrilaș LI, Candrea R, Cătinean A, Mocan A, Miere D, Tătaru A. Gut Microbiota in Psoriasis. Nutrients. 2022; 14(14), 2970


13. Mary Ellen S, Francisco G, Richard G et al. An update on the use and investigation of probiotics in health and disease. Gut. 2013;62(5):787


targeting the gut microbiome could be skin care future, with the goal to achieve a balanced and holistic equilibrium through the gut-skin axis, and to make one look good and to feel good. This can be done as we continue to scientifically understand the skin-gut axis, the key to healthy skin from the inside out.


14. Hill C, Guarner F, Reid G et al. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. NatRev Gastroenterol Hepatol. 2014;11(8):506-514


15. Bowe WP, Logan AC. Acne vulgaris, probiotics and the gut-brain-skin axis - back to the future? Gut Pathog. 2011; 3, 1


PC


References 1. De Pessemier B, Grine L, Debaere M, Maes A, Paetzold B, Callewaert C. Gut–Skin Axis: Current Knowledge of the Interrelationship between Microbial Dysbiosis and Skin Conditions. Microorganisms. 2021; 9(2), 353


2. Polak K, Bergler-Czop B, Szczepanek M, Wojciechowska K, Frątczak A, Kiss N. Psoriasis and Gut Microbiome—Current State of Art. International Journal of Molecular Sciences. 2021; 22(9), 4529


3. Salem I, Ramser A, Isham N, Ghannoum MA. The gut microbiome as a major regulator of the gut-skin axis. Frontiers in Microbiology. 2018; 9, 1459


4. Grice E, Segre J. The skin microbiome. Nat Rev Microbiol. 2011; 9, 244–253


5. O’Neill CA, Monteleone G, McLaughlin JT, Paus R. The gut-skin axis in health and disease: A paradigm with therapeutic implications. BioEssays. 2016; 38(11), 1167- 1176


6. Mahmud MR, Akter S, Tamanna SK, Mazumder L, Esti IZ, Banerjee S, Akter S, Hasan MR, Acharjee M, Hossain MS, Pirttilä AM. Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases. Gut Microbes. 2022; 14(1)


7. Mallott EK, Sitarik AR, Leve LD, Cioffi C,


16. Fouesnard M, Zoppi J, Petera M, le Gleau L, Migné C, Devime F, Durand S, Benani A, Chaffron S, Douard V et al. Dietary Switch to Western Diet Induces Hypothalamic Adaptation Associated with Gut Microbiota Dysbiosis in Rats. Int. J. Obes. 2021, 45, 1271–1283


17. Nazzaro F, Fratianni F, De Feo V, Battistelli A, Da Cruz AG, Coppola R. Polyphenols, the new frontiers of prebiotics. Adv Food Nutr Res. 2020;94:35-89


18. Zhou P, Chen C, Patil S, Dong S. Unveiling the Therapeutic Symphony of Probiotics, prebiotics, and postbiotics in gut-immune harmony. Front Nutr. 2024; vol. 11


19. Pistone D, Meroni G, Panelli S, D’Auria E, Acunzo M, Pasala AR, Zuccotti GV, Bandi C, Drago L. (2021). A Journey on the Skin Microbiome: Pitfalls and Opportunities. International journal of Molecular Sciences. 2021; 22(18), 9846


20. De Almeida CV, Antiga E, Lulli M. Oral and Topical Probiotics and Postbiotics in Skin care and Dermatological Therapy: A Concise Review. Microorganisms. 2023; 11(6), 1420


21. Laudisi F, di Fusco D, Dinallo V, Stolfi C, di Grazia A, Marafini I, Colantoni A, Ortenzi A, Alteri C, Guerrieri F et al. The Food Additive Maltodextrin Promotes Endoplasmic Reticulum Stress-Driven Mucus Depletion and Exacerbates Intestinal Inflammation. Cell. Mol. Gastroenterol. Hepatol. 2019, 7, 457–473


June 2025 PERSONAL CARE


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