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ANTI-AGEING


49


Interkingdom harmony for ever-blooming female skin


Clara Vigo, Elizabeth Escudero, Silvia Benito - Provital


Triplobiome technology is a groundbreaking biotech platform that is pioneering a new category of ecosystem postbiotic ingredients by harnessing the powerful relationships between plants and their internal symbiotic microorganisms. By combining the symbiotic intelligence


of plants and their microbiomes, it creates a unique synergy that extends beyond the microbiome discussion. This platform introduces a transformative approach to beauty, infusing products with the adaptive and protective power of nature itself. The platform’s uniqueness lies in its


symbiotic synergy with endophytes — microorganisms living within plant tissues. Through evolutionary adaptation, these endophytes have developed the ability to produce a wide range of metabolites, including plant compounds, providing resilience and protection to their host plants against environmental stressors.1 By isolating and using endophytes to


produce active ingredients, this technology allows the transfer of the protective benefits of this natural symbiosis to the skin, supporting skin health and resilience. This metabolic versatility unlocks vast potential for various cosmetic applications, allowing for the development of ingredients with diverse, multifaceted benefits.


The first agro-psychological solution for women ‘in bloom’ Guided by nature, this endophytic ferment bridges the gap between advanced dermocosmetics and a more natural, holistic approach to women’s wellbeing. With an agro- psychological perspective, the purity of nature reflects the purity of healthy, balanced skin. It embodies a holistic blend of psychological


balance, physical renewal, and sustainable production, offering modern mature women a way to reconnect with nature’s wisdom. Just as ecosystems thrive in harmony, skin radiates vitality when its natural balance is restored. This ingredient represents a cosmetic concept that transcends holistic health, embracing the interconnectedness of humans and the environment. Thanks to its unique biotechnology, a


collection of endophytic strains was isolated and screened for bioactivity to identify the most promising candidates for beauty development. In this case, the high bioactive endophytic


www.personalcaremagazine.com bacterium Bacillus velezensis2 was isolated


from the leaf tissue of agroecologically grown hyssop (Hyssopus officinalis) sourced from the mediterranean plants’ cultivator, Parc de les Olors. This plant, valued for its aromatic and medicinal properties, has long been recognized for its antimicrobial effects. Recently, it has shown strong antibacterial activity against Cutibacterium acnes (C. acnes).3 After being isolated and bio-optimized


through controlled bio-fermentation, a Metabolomic Analysis was conducted on the B. velezensis ferment. This endophytic bacterium aids its host plant’s survival and growth by producing peptides, lipopeptides, and other anti-pathogenic molecules. These compounds not only exhibit biocontrol


activity against a wide range of phytopathogens but also highlight the potential for cosmetic ingredients addressing ageing, acne, and inflammation. By standardizing it in peptides, Provital ensures that the metabolic intelligence from the symbiotic relationship between hyssop and B. velezensis is transferred to the skin.


ABSTRACT


In recent years, the conversation around femininity has evolved, blending empowerment, timeless beauty, and self- actualization. This transformation signifies a profound shift in the demands of adult women for beauty products. Pureblome™ bridges advanced scientific cosmetics with a holistic approach to wellbeing. Through an agro-psychological lens, it emphasizes the purity of nature as a reflection of healthy, balanced skin. Developed by Triplobiome™ technology, this new active ingredient is the result of the isolation of Bacillus velezensis bacteria from the leaves of an agroecologically grown hyssop (Hyssopus officinalis). This novel, 100%-traceable ecosystem ingredient harnesses the metabolic intelligence of the plant-bacteria symbiosis, transferring nature’s balance and regenerative power directly to the skin. This innovative post-biotic ingredient balances the skin, addressing the complex needs of mature women. Its triple-efficacy approach improves acne, oily skin and inflammation while preventing ageing signs, thus promoting balanced and rejuvenated skin


All in all, this new ecosystem ingredient is


developed: a 100% traceable, eco-responsible and biotechnologically obtained cosmetic active that - thanks to its symbiotic provenance - delivers nature’s balance, resilience, and regenerative power directly to the skin.


Triple action efficacy for balanced feminine harmony By harnessing the synergistic power of nature and science, this endophytic ferment redefines skin care for women in their blooming years. This innovative post-biotic ingredient purifies the skin and tackles the diverse challenges faced by mature women, offering a triple-action approach that combines anti-acne, anti- inflammatory and anti-ageing benefits. Backed by advanced in vitro and in vivo


research, this innovative active ingredient effectively supports overall skin regeneration by targeting different cell types and offering a holistic approach to preventive skin care, empowering women to thrive in beauty and confidence.


May 2025 PERSONAL CARE


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