HAIR CARE
43
Placebo ■ Portulaca Vita 0.5% ■
30 25 20 15 10 5 0
+25.66% *
T0
D7
D28
+11.56% *
D7
D28
Figure 7: Effect of Portulaca Vita on scalp hydration (A) and illustrative pictures of scalp conditions after treatment application (B) Furthermore, the Portulaca olearacea
was carried out on a panel of 44 female and male test subjects (distributed into two independent groups), between 19 and 67 years old, with dryness, flaking and itchiness on the scalp. For four weeks, every other day, the volunteers applied a leave-on lotion containing 0.5% Portulaca olearacea extract or a placebo lotion. Measurements of scalp hydration
(Corneometer CM 825), itchiness (VAS scale) and scalp desquamation (Dandruff Mean Score IDMS method) were carried out at baseline, after seven days (D7) and 28 days (D28) treatment by an expert clinician. Microscopic analysis of the scalp was taken by means of Trichoscan HD (DermoScan) to evaluate the scalp conditions compared to the placebo group. The significance was calculated according
to a p-value of bilateral Student's t-test in pairs, in the case of normality of the distribution or the Wilcoxon test in the adverse case. The variations are judged statistically significant if p<0.05.
Conclusions In vitro and in vivo testing have demonstrated that the Portulaca olearacea extract possesses soothing efficacy which improves skin and scalp conditions. Thanks to its multiple actions, the Portulaca olearacea extract has proven significant effects on the regulation of several genes and parameters involved in epidermal water homeostasis, immune response, and skin barrier repair. Two independent clinical tests proved that the action can be a protective and beneficial ingredient for subjects experiencing skin irritancy. The soothing effect on the face was visible as a reduction in redness (erythema), inflammation, and itching sensation. On the scalp, the Portulaca olearacea extract has proven efficacy in reinforcing the epidermal barrier function, attenuating the perception of itch, and reducing flake appearance.
www.personalcaremagazine.com
extract is 100% of natural and organic origin, which makes it a suitable ingredient in products which enter the green, sustainable, and eco-friendly category. An effective ingredient is designed for skin and scalp care preparations to strengthen stratum corneum integrity, recovery, and protection, even for the most fragile skins.
References 1. Proksch E, Brandner JM, Jensen JM. The skin: an indispensable barrier. Exp. Dermatol. 17, 1063–1072 (2008)
2. Roberts W. Air pollution and skin disorders. Int. J. Womens Dermatol. 7, 91–97 (2021)
3. Saint-Martory C et al. Sensitive skin is not limited to the face. Br. J. Dermatol. 158, 130–133 (2008)
4. Misery L et al. Definition of Sensitive Skin: An Expert Position Paper from the Special Interest Group on Sensitive Skin of the International Forum for the Study of Itch. Acta Derm. Venereol. 97, 4–6 (2017)
5. Willis CM et al. Sensitive skin: an epidemiological study. Br. J. Dermatol. 145, 258–263 (2001)
6. Berardesca E, Farage M, Maibach H. Sensitive skin: an overview. Int. J. Cosmet. Sci. 35, 2–8 (2013)
7. Rattanakaemakorn P, Suchonwanit P. Scalp Pruritus: Review of the Pathogenesis, Diagnosis, and Management. BioMed Res. Int. 2019, 1268430 (2019)
8. Zhou Y-X et al. Portulaca oleracea L.: A Review of Phytochemistry and Pharmacological Effects. BioMed Res. Int. 2015, 925631 (2015)
9. A review on bioactive phytochemicals and ethnopharmacological potential of purslane PubMed.
https://pubmed.ncbi.nlm.nih. gov/35028454/
10. Waleckx E, Gschaedler A, Colonna-Ceccaldi B, Monsan P. Hydrolysis of fructans from Agave tequilana Weber var. azul during the cooking step in a traditional tequila elaboration
process. Food Chem. 108, 40–48 (2008)
11. Box JD. Investigation of the Folin-Ciocalteau phenol reagent for the determination of polyphenolic substances in natural waters. Water Res. 17, 511–525 (1983)
PC
12. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248–254 (1976)
13. Hashizume H. Skin Aging and Dry Skin. J. Dermatol. 31, 603–609 (2004)
14. Boury-Jamot M et al. Skin aquaporins: function in hydration, wound healing, and skin epidermis homeostasis. Handb. Exp. Pharmacol. 205–217 (2009) doi:10.1007/978- 3-540-79885-9_10
15. Sayo Tet al. Hyaluronan synthase 3 regulates hyaluronan synthesis in cultured human keratinocytes. J. Invest. Dermatol. 118, 43–48 (2002)
16. Pasonen-Seppänen S et al. Role of CD44 in the organization of keratinocyte pericellular hyaluronan. Histochem. Cell Biol. 137, 107–120 (2012)
17. Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O. Oxidative Stress and Antioxidant Defense. World Allergy Organ. J. 5, 9–19 (2012)
18. Gutowska-Owsiak D et al. The histamine- synthesizing enzyme histidine decarboxylase is upregulated by keratinocytes in atopic skin. Br. J. Dermatol. 171, 771–778 (2014)
19. Kerr K et al. Scalp stratum corneum histamine levels: novel sampling method reveals association with itch resolution in dandruff/ seborrhoeic dermatitis treatment. Acta Derm. Venereol. 91, 404–408 (2011)
20. Bacon RA, Mizoguchi H, Schwartz JR. Assessing therapeutic effectiveness of scalp treatments for dandruff and seborrheic dermatitis, part 2: the impact of gender and ethnicity on efficacy. J. Dermatol. Treat. 25, 237–240 (2014)
21. Ceccacci S et al. An Oenothera biennis Cell Cultures Extract Endowed with Skin Anti- Ageing Activity Improves Cell Mechanical Properties. Metabolites 11, 527 (2021)
January 2023 PERSONAL CARE
% variation vs T0
Volunteer ref.43
Volunteer ref.22
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68
