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SUN CARE 43


magnification of 600. Figure 5 shows electron microscope images after ultraviolet ray irradiation. For the surface of the hair treated with water and irradiated with ultraviolet rays, we observed problems such as cuticle exfoliation. In comparison, the hair processed with 5% aqueous solution of the hair care fullerene exhibited a better and smoother surface. For an experiment in which we applied an aqueous solution of the hair care fullerene to hair and measured the amount of cysteic acid in hair before and after ultraviolet ray irradiation (approximately 300 J/cm2), we observed that there was an increase in cysteic acid in water-treated hair, whereas in the hair treated with the hair care fullerene, no increase in cysteic acid was observed (Fig 6). Therefore, these experimental results for hair irradiated with ultraviolet rays confirm that continuous use of fullerene can be considered effective for sun care of skin as well as hair.


Conclusion


When we think about sun care, we tend to think only about ultraviolet ray blocking and the SPF values of sunscreens; however, if ROS generated by ultraviolet rays is eliminated by an anti-oxidant, sun care may not be sufficient in achieving its purpose of preventing damage. We present fullerene raw materials that


provide two functions—providing antioxidant action for skin care and improving the ultraviolet ray absorption ability of sunscreens. We also offer fullerene raw materials that reduce ultraviolet ray damage to hair. By using our fullerene raw materials, overall sun care is possible for skin and hair by blocking ultraviolet rays and providing antioxidants. More than 13 years since these fullerene raw materials for cosmetics were first introduced in the market by us, their usage history has been increasing and various tests, such as clinical trials, have been performed. We are offering customers the high safety and best stability with Japanese quality. Next, for exploring new possibilities for fullerene-based sun care, we are conducting experiments such as verifying the effects of pre-mixing.


PC Water Treatment b a


No Application 0 -0.5 -1.0 -1.5 p<0.074 -7.0 -7.5 -8.0 No Application


Fullerene Not Blended In


1% Sun Guard Fullerene A Blended In


Fullerene Not Blended In


1% Sun Guard Fullerene A Blended In


Figure 4: Results of the sun guard fullerene clinical trial. Δa Mean Value (n = 10) Photographs of Representative Examples


References 1 Kenji M. The application of fullerenes for


cosmetics. Manufacturing and Technology. 2008; 60(1): 50-54.


2 Takada H, Kokubo K, Matsubayashi K, Oshima T. Antioxidant activity of supramolecular water- soluble fullerenes evaluated by beta-carotene bleaching assay. Biosci Biotechnol Biochem. 2006; 70(12): 3088-93.


3 Kato S, Taira H, Aoshima H, Saitoh Y, Miwa N. Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics. J Nanosci Nanotechnol. 2010; 10(10): 6769-74.


4 Inui S, Aoshima H, Nishiyama A, Itami S. Improvement of acne vulgaris by topical fullerene application: unique impact on skin care. Nanomedicine. 2011; 7(2): 238-41.


5% Hair Shiny Fullerene® Treatment


5 Inui S, Mori A, Ito M, Hyodo S, Itami S. Reduction of conspicuous facial pores by topical fullerene: possible role in the suppression of PGE2 production in the skin. J Nanobiotechnology. 2014; 22; 12:6.


6 Murakami M, Hyodo S, Fujikawa Y, Fujimoto T, Maeda K. Photoprotective effects of inclusion complexes of fullerenes with polyvinylpyrrolidone. Photodermatol Photoimmunol Photomed. 2013; 29(4): 196-203.


0.4 0.35 0.3 0.25 0.2 0.15 0.1 0.05 0


Treatment Water


 Before UVA Irradiation  After UVA Irradiation


HF: Hair Shiny Fullerene


Figure 5: Hair surface after ultraviolet light irradiation. May 2019


Figure 6: Suppression of the increase in cysteic acid in hair due to ultraviolet rays by the use of fullerene.


PERSONAL CARE NORTH AMERICA


5%-HF


∆a


A1040 cm^-1/A1634 cm^-1


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