42 SUN CARE 1 ppm Fullerene-Blended Sunscreen Sunscreen Without Fullerene Blended In 1
0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0
-0.1 250 300 350 Wavelenght (nm) 400 450 Figure 3: Increase in ultraviolet light absorbance ability by blending in fullerene.
To further investigate the effects and applications of fullerene raw materials for cosmetics, we blended fullerene into sunscreen creams. We added LipoFullerene to a sunscreen preparation, which included ethylhexyl methoxycinnamate and t-butyl methoxydibenzoylmethane, and used an SPF analyser to study the change in ultraviolet rays absorption due to the presence of fullerene. As shown in Figure 3, the addition of 1 ppm of fullerene (C60) to the sunscreen improved the ultraviolet ray absorption (integrated value) by approximately 20%. The same concentration of fullerene without blending in any preparation has no ultraviolet rays absorption; thus, the increase in ultraviolet absorption by sunscreens containing fullerene is believed to be caused by the
booster effect attributed to the presence of fullerene.
However, improvement in the usage sensation is an important aspect of sunscreen product development. It was expected that adding oily fullerene to an existing sunscreen formulation would worsen the usage sensation. If a raw material is developed in which fullerene is dispersed in ethylhexyl methoxycinnamate, which is an ultraviolet ray absorber, fullerene can be blended into a sunscreen formulation without affecting the usage sensation. Based on this concept, we developed fullerene-dispersed ethylhexyl methoxycinnamate. We conducted a clinical trial to verify the
effect of blending fullerene-dispersed ethylhexyl methoxycinnamate into a
Table 2: Sunscreen formulation used in the clinical trial. Item Display Name (Product Name)
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, isohexadecane, polysorbate 60
Polysorbate 60 A
Ethylhexyl methoxycinnamate Butyl Methoxydibenzoylmethane Triethylhexanoin Squalane
B
Sun Guard Fullerene® A Butylene Glycol Phenoxyethanol Water
Total (%) PERSONAL CARE NORTH AMERICA Sun Guard
Control Sunscreen (without Fullerene)
2.0
1.0 7.0 3.0 5.0 5.0 0
5.0
0.40 71.6
100.0
Fullerene A(1%) blended sunscreen
2.0
1.0 6.0 3.0 5.0 5.0 1.0 5.0
0.40 71.6
100.0
of each sunscreen formulation and irradiated the application site with ultraviolet rays (1.5 MED) using a solar simulator. We measured the skin color (a* value) of the trial site before and after ultraviolet rays irradiation to show the change in the skin color of the irradiated site, obtained as the Δa* value. The site where the sunscreen formulation including fullerene was applied showed a clear tendency to suppress the increase in redness, as compared to the site where the sunscreen formulation without fullerene was applied, indicating that fullerene has an effect in suppressing redness (Fig 4). From this result, in addition to increasing ultraviolet ray absorption, fullerene may also contribute to the anti-inflammatory effect, caused by the antioxidant action of fullerene. Thus, it can be said that blending fullerene-dispersed ethylhexyl methoxycinnamate into a sunscreen formulation, which is important for sun care, is effective against photoaging.
sunscreen formulation. Without changing the total amount of the ultraviolet rays absorber that is blended in, we prepared sunscreen formulations that either did or did not include fullerene (Table 2). There were ten subjects, who consented for the trial, and the trial application site was the inside of the upper arm. We applied 1 mg/cm2
Fullerene raw material designed for hair care items Sun care is synonymous with skin; however, hair is also damaged by ultraviolet rays. Hair exposed to ultraviolet rays suffers cuticle damage. Also, the disulfide bonds, which form the basic structure of hair, are oxidized by ROS generated by ultraviolet rays, thereby increasing cysteic acid. Hair Shiny Fullerene is a raw material that is designed for hair care; it received the silver medal in the Functional Raw Material category of the 2018 BSB Innovation Prize Awards. This raw material has a bicontinuous structure, and is a blend of fullerene, which can protect hair from ROS that is generated by ultraviolet rays and residual hydrogen peroxide, and -docosalactone, which has a repairing
effect on hair. This easily forms a nanoemulsion on adding water and mixing; we have verified that this emulsion penetrates into the hair. We shampooed black human hair (Beaulax BS-B3A) twice and dried it with a dryer. We sprayed with either water or 5% aqueous solution of the hair care fullerene and dried again with a dryer. We repeated this treatment five times. We attached the hair to aluminum foil, lightly sprayed with water, and then irradiated it with UVB (18 J/cm2
). We fixed several hair strands to a sample stand and observed them with a scanning electron microscope at a
May 2019
Light Absorbance
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