40 SCALP CARE
Control
UVB-induced 0.025% 0.05% 0.1%
120 100 80 60 40 20 0
LPS
ROS-FITC assay ** **
***
LPS +0.025%
LPS +0.05%
LPS +0.1%
Control
Figure 1: The effect of Sarcodia suiae extract on reducing ROS in the HaCaT cell line after UV-B irradiation IL-6 150 100 50 0 LPS LPS LPS +0.025% +0.05% IL-8 150 100 50 0 LPS LPS LPS +0.025% +0.05% LPS +0.1% Nitric oxide (NO)
50 40 30 20 10 0
LPS *** *** *** Control *** *** *** LPS +0.1% Control *** *** ***
to reduce both dandruff and acne formation. These results underscore its potential as a high-performance active ingredient in scalp and skincare formulations.
Extraction and sustainability We cultivate Sarcodia suiae using an innovative aquaponic system that integrates fish farming with algae production.10
produced, represents a next-generation active ingredient for multifunctional cosmetic formulations.
This method enables the
algae to efficiently absorb organic nutrients from aquaculture wastewater, which not only improves resource utilization but also significantly enhances its growth and functional properties. Compared with conventional filtered
seawater systems, this approach doubles the biomass growth rate and increases the carbon sequestration capacity of Sarcodia suiae by approximately 2.5 times. Notably, this cultivation method also enhances the antioxidant and anti- inflammatory activities of the harvested algae, further reinforcing its value as a high-performance bioactive ingredient. During cultivation, we utilize cooled discharge
water from Taiwan’s CNPC liquefied natural gas (LNG) terminal—a byproduct referred to locally as ‘diamond water’. This resource is provided free of charge to local farmers and offers a sustainable alternative water source. Its naturally low temperature and minimal
bacterial load significantly improve the cultivation efficiency of Sarcodia suiae while conserving energy and reducing carbon emissions. By incorporating this otherwise discarded industrial byproduct into algae farming, the process supports both environmental conservation and enhanced bioactive compound quality. The Sarcodia suiae extract used in this study
LPS LPS +0.025% +0.05% LPS +0.1%
Figure 2: Sarcodia suiae extract significantly reduces the levels of inflammatory factors in macrophages after LPS induction and exhibits anti-inflammatory effects
PERSONAL CARE MAGAZINE October 2026 Control
is a pale-yellow aqueous solution obtained through a controlled drying and chromatographic extraction process. The production process aligns with circular economy principles—post-extraction algal residues are repurposed into recycled paper products, effectively minimizing waste and further supporting our commitment to sustainability. This extract, both potent and eco-consciously
In vitro studies Anti-oxidation As shown in Figure 1, UVB-irradiated HaCaT cells produced high levels of ROS. Pretreatment with 0.025%, 0.05%, and 0.1% Sarcodia suiae extract reduced ROS levels by approximately 30%, 40%, and 78%, respectively, demonstrating strong antioxidant efficacy.
Anti-inflammatory As shown in Figure 2, pretreatment with 0.025%, 0.05%, and 0.1% Sarcodia suiae extract significantly reduced the levels of LPS-induced inflammatory factors in macrophages, including IL- 6, IL-8, and NO. At 0.1% concentration, the extract decreased the production of these inflammatory mediators by approximately 50%, demonstrating its strong anti-inflammatory effect.
Anti-allergic C48/80-stimulated mast cells exhibited decreased release of allergic mediators (IL-4 and histamine) when pretreated with 0.1% Sarcodia suiae extract. Inhibition rates reached 43% for IL-4 and 34% for histamine (Figure 3).
Sebum Regulation Oil Red O staining results (Figure 4) showed that 0.1% Sarcodia suiae extract significantly reduced lipid accumulation in sebocytes. The lipid content decreased by over 40%, confirming its sebum- suppressing efficacy.
Anti-microbial The antimicrobial efficacy of Sarcodia suiae extract was evaluated using two methods. In the agar diffusion test, a zone of inhibition greater than 20 mm is generally considered indicative of strong antimicrobial activity. In our study, 2% Sarcodia suiae extract
produced an inhibition zone of ≥43 mm against
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NO production (ug/mL)
IL-8 (UG/mL)
IL-6 (UG/mL)
% Fluorescence Intensity (Relative to UVB)
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