48 SKIN MICROBIOME Before treatment After treatment
Figure 6: Effect on hydration of the skin of Caucasian volunteers (hands).
volunteers (+15.8%, P < 0.001). Evaluation of complexion radiance The effect of the postbiotic on complexion radiance was assessed on two panels of Caucasian and Asian volunteers: The Caucasian panel was composed of 18 healthy volunteers having applied the ingredient and the placebo to each half of the face in the morning and evening;
The Asian panel was composed of 31 healthy volunteers having applied the ingredient and the placebo to each half of the face in the morning and evening. Trained evaluators assessed the complexion radiance of volunteers with a scoring scale. After 28 days of twice-daily application and in comparison to the placebo, the ingredient tested at 1% improves luminosity in Caucasian volunteers by significantly increasing reflection of the skin (+7.4%, P < 0.01), pink colour representing a fresh complexion (+14.7%, P < 0.01) and the healthy-glow effect (+6.4%, P < 0.05) as well as significantly decreasing the olive colour (-9.2%, P < 0.05). In Asian volunteers, the reflection of the skin is significantly increased (+13.6%, P < 0.001), as well as uniformity of complexion (+6.0%, P < 0.05), and skin
Before application
hydration (+7.0%, P < 0.05) (Fig 7). Tested on the face and hands of female and male Caucasian and Asian volunteers, this active ingredient improves the quality of dry skin by restoring their hydration and luminosity while maintaining the equilibrium of their microbiota.
Conclusion With Lactobiotyl®
, Silab offers a specific
solution for dry skin to the cosmetics market, which has been developed by combining three major fields of competence from the company: microbiota, mastering natural and biotechnologies.
Silab took advantage from the extensive studies conducted revealing the positive effects of postbiotics on the body and transposed them to the skin in order to improve the integrity of its barrier. In order to produce this postbiotic, Silab used a biomimetic approach based on reproducing the natural environment of Lactobacillus arizonensis, a bacterium having acquired the capacity to survive in the extreme drought conditions of the Arizona desert. By cleverly nourishing and stimulating the strain with its natural substrate, its
metabolism was bioguided so that it produces specific metabolites that improve the quality of dry skin.
Lactobiotyl is thus a natural solution that acts on the different levers responsible for epidermal homeostasis, thereby improving hydration of the skin and reviving the complexion radiance of Caucasian and Asian volunteers. This biotech active ingredient is patented (INCI name: Maltodextrin and Lactobacillus Ferment), available as a powder without preservatives (recommended amount: 0.1 to 1%) and compliant with international cosmetic regulations (Europe, United States, Japan, China, etc.). With this natural active ingredient, Silab demonstrates the value of a natural postbiotic for the treatment of dry skin.
PC
References 1 Gosálbez L, Ramón D. Probiotics in transition:
novel strategies. Trends Biotechnol. 2015;33(4):195–6.
2 Siezen RJ, van Hylckama Vlieg JET. Genomic diversity and versatility of Lactobacillus plantarum, a natural metabolic engineer. Microb Cell Fact. 2011;10 Suppl 1:S3.
After 28 days of application
Figure 7: Effect on complexion radiance of the skin in Asian volunteers. PERSONAL CARE EUROPE February 2020
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