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Thursday PM ~Platform! 147


4:15 PM 884 ~Invited! Structure of HIV Capsid and Inter- actions with Rhesus TRIM5a; G Zhao, XMeng,D Ke, T Vu, J Ahn; University of Pittsburgh; V Shah, R Yang, C Aiken; Vanderbilt University; L Charlton, A Gronenborn, P Zhang; University of Pittsburgh


4:45 PM 885 CryoEM Structure of the Adenovirus Factor X Complex at Subnanometer Resolution; J Flatt, S Lindert, D Williams;Vanderbilt UniversityMedical Center; D Shayakh- metov; University of Washington; P Stewart; Vanderbilt University Medical Center


B-07Multi-scale Approach to Amyloid Diseases Session Chairs:


Martin Muschol, University of South Florida Helen McNally, Purdue University


George Perry, University of Texas, San Antonio PlatformSession


Thursday 1:30 PM Room: 110/111


1:30 PM 886 ~Invited! Nanoimaging for Protein Misfold- ing Diseases. Critical Role ofMisfolded Dimers in the Amyloid Self-Assembly; A Krasnoslobodtsev, B-H Kim, Y Lyub- chenko; University of Nebraska Medical Center


2:00 PM 887 Integrating Atomic Force Microscopy for Si- multaneous Investigations; HMcNally; Purdue University; D D’Agostino; University of South Florida


2:15 PM 888 Substitutionally Enhanced STEM (SE-STEM) Imaging of Protein Aggregates Inside Cells; EMcGuire; Impe- rial College London, United Kingdom; M Motskin, C Dob- son; University of Cambridge,United Kingdom; A Porter,D McComb; Imperial College London, United Kingdom


2:30 PM 889 ~Invited! YeastModels for Amyloid Disorders; Y Chernoff, M Sun, H Gong, G Newnam, D Kiktev, K Bruce, R Howie, T Pan, A Romanyuk; Georgia Institute of Technology


3:00PM 890 ~Invited! Controlling Proteotoxicity with Chap- eroneProteins; C Dickey; University of South Florida


3:30 PM 891 Charge Repulsion and Salt-Mediated Charge Screening as Regulators of Amyloid Assembly Pathways;M Muschol, S Hill, T Miti; University of South Florida


3:45 PM 892 Analysis of Adenovirus-Vectored Foot-and- Mouth Disease Virus Transgene Expression in Bovine Kidney Cells by Confocal, Electron, and Immuno-Electron Micros- copy; T Burrage,M Grubman, D Brake, J Neilan, E Kramer; Plum Island Animal Disease Center; D Brough; GenVec, Inc; B Harper; Plum Island Animal Disease Center


4:00 PM 893 ~Invited! In Vivo Visualization of Amyloid- Like Structures in Humans; V Kepe, G Small, J Barrio; University of California, Los Angeles


B-08 ImagingMitochondia and Other Organelles in Health and Disease


Session Chair:


Heidi Schatten, University of Missouri PlatformSession


Thursday 1:30 PM Room: 102


1:30 PM 894 Preliminary Investigations into the Utiliza- tion of Electron Tomography and Immunogold Immunocyto- chemistry in the Diagnosis ofMitochondrial Disease inMuscle; C Ackerley; Hospital for Sick Children, Toronto Canada


1:45 PM 895 ~Invited!~MSA PTSA Award! Assessment of a Mitotoxic and Oxidant-Based Strategy in Carcinoid Can- cers; S Zahedi, T Zhelay, D Giovannucci; University of Toledo


2:00 PM 896 Ultrastructural Observation of Mitochondria in Human Breast Carcinoma Cells; R Elliott, B Barnett; Elliott Elliott Head Breast Cancer Research and Treatment Center


2:15 PM 897 ~Invited! Mitochondrial Fragmentation Me- diates MPP+ Toxicity in Neurons: Implications for Parkinson’s Disease; X Wang, M Smith; Case Western Reserve Univer- sity; G Perry; University of Texas at San Antonio; X Zhu; CaseWestern Reserve University


2:45 PM 898 The Use of Time Lapse Imaging to Study the Effect of Hyperphosphorylated Tau; C Corbo, E Alaniz, M Farid, A Alonso; CUNY Staten Island


3:00 PM 899 ~Invited!Mitochondrial Abnormalities in Alz- heimer’s Disease; G Perry; University of Texas at San Anto- nio; X Wang, M Smith, X Zhu; Case Western Reserve University


3:30 PM 900 ExaminingMitochondrial Nucleoid Structure and Organization by Correlative Super-Resolution Fluores- cence and Electron Microscopy; B Kopek, T Brown, A Tka- chuk, D Clayton; Howard Hughes Medical Institute, Janelia Farm Research Campus


3:45PM 901 Liquid Scanning Transmission ElectronMicros- copy AppliedtoStudy Live Cells; D Peckys, N de Jonge; Vanderbilt University


4:00 PM 902 ~Invited! The Structure of Mitochondria, a Study Using High-Pressure Freezing and STEM Tomography; P Walther, K Höhn; Ulm University, Germany; L Wang; University Hospital, Germany


4:30 PM 903 ~Invited! Testing a Computational Model of Pancreatic Beta-Cell Oscillations Using Live-Cell Imaging of Islet Oscillatory Behavior; MJ Merrins; University of Michi- gan; R Bertram; Florida State University; A Sherman; Na- tional Institutes of Health; LS Satin; University of Michigan


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