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ADVERTISEMENT FEATURE COVER STORY: SESDERMA
create solutions that work both inside and out, reinforcing skin health through a truly 360° scientific strategy.
Mediderma solutions Our professional brand Mediderma is the extension of our dermatological expertise. It provides physicians and aestheticians with medical-grade peels, boosters, regenerative treatments, and cutting-edge medical devices that complement the daily homecare provided by Sesderma products. The key is synergy without overlap—both lines share the same scientific backbone, based on liposomal and nanotechnological delivery systems, ensuring a seamless transition between professional treatments and home maintenance. Among our most successful innovations are the NANOPORE devices, such as NANOPORE Stylus 02 and NANOPORE Pen 02, which have become international benchmarks in microneedling technology, outperforming other systems in precision, safety, and clinical efficacy. Recently, we also introduced NANOPORE EMSES RF, a device whose efficacy lies in the synergy of four advanced technologies: Radiofrequency (RF) improves elasticity, reduces sagging, and smooths wrinkles; Microcurrent (EMS) stimulates new collagen synthesis and enhances microcirculation; Blue LED light improves active absorption and delivers anti-inflammatory, soothing effects; and rotational stimulation reinforces the lifting and tightening action. The result is visibly firmer, revitalized skin achieved through advanced, non-invasive technology. In parallel, Mediderma continues to innovate
in exosome-based therapies, working closely with Sesderma on the EXOSES Medical line—a new generation of regenerative treatments that use probiotic-derived exosomes (Lactobacillus brevis) combined with liposomal lactoferrin to stimulate the skin’s natural repair mechanisms
PERSONAL CARE MAGAZINE January 2026
and collagen production up to four times more effectively. These protocols—EXOSES LB+, LA, LW, and GF—offer tailored medical-aesthetic solutions for luminosity, firmness, depigmentation, and hair restoration, providing visible results from the very first sessions.
Growth Our growth model is based on scientific discipline and logistical resilience. We mitigate supply-chain risk through dual sourcing of key ingredients, validated alternative manufacturers, and strategic raw-material reserves. Regulatory divergence is addressed via a centralized regulatory-intelligence team monitoring every market—from the EU Omnibus Acts to MoCRA and Asian standards. Brand coherence is protected through strict
training and content control. Every distributor and subsidiary undergoes scientific onboarding so that a Sesderma product in Dubai or Bogotá delivers the same message and results as in Valencia. Our digital education ecosystems and KOL networks ensure that global expansion never compromises the integrity of the brand.
EXOSES line of exosomes Exosomes are one of the most exciting frontiers in dermatological research—microscopic messengers that enable cell-to-cell communication and natural skin regeneration. Sesderma was the first Spanish laboratory to incorporate exosomes into cosmetic formulations, launching EXOSES Serum and Cream, which deliver visible improvements in firmness, elasticity, and luminosity within 28 days. Our EXOSES products use Lactobacillus-
derived exosomes, combined with advanced actives such as HP Retinoate, niacinamide, hyaluronic acid, organic silicon, and arbutin, all
encapsulated in our Nanotech liposomes for optimal penetration and tolerance. Objective testing showed up to +38 % firmness and +17 % elasticity after four weeks. In parallel, our professional
brand Mediderma introduced EXOSES Medical, a regenerative treatment
line based on probiotic-derived exosomes (Lactobacillus brevis) and liposomal lactoferrin, capable of stimulating collagen synthesis up to four times more effectively. These protocols—EXOSES LB+, LA, LW, and GF—offer visible improvements in luminosity, firmness, pigmentation, and hair density from the first sessions. Currently, our R&D department is also
developing a new generation of exosomes derived from milk combined with liposomal lactoferrin, exploring their anti-ageing, depigmenting, and hair-loss-prevention potential. This research represents the next step in Sesderma’s mission to translate molecular science into safe, effective, and truly regenerative skincare.
Novel uses of exosomes Beyond EXOSES, several new projects are underway to extend the application of exosomes into specific dermatological and intimate-care areas. One of them is AZELAC RU Dark Circles with Exosomes, a breakthrough treatment designed to target periorbital pigmentation and microcirculatory imbalance, improving luminosity and reducing dark circles through regenerative communication pathways. Another innovative product, NANOCARE
Intimate with Exosomes, addresses female intimate wellness by improving tone, elasticity, and muscle firmness, while promoting healthy lubrication and tissue regeneration. Its formula combines papaya extract, wheat germ, rucinol,
www.personalcaremagazine.com
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