INTERVIEW 19 We also have other ranges like
Prodigy Cellglow, which is focused on cellular reprogramming, and we also have Powercell, which is focused on cellular regeneration and defence. Second, we partner with key
scientific experts. The Helena Rubinstein Replasty skin care range, for example, was inspired by our partnership with Dr. Michel Pfulg, a world-renowned aesthetic surgeon and the founder of the Laclinic- Montreux anti-ageing clinic in Switzerland. Thirdly, we are always trying to
source greentech actives in order to include in our formulations. Another factor is balancing luxury
formulation and science. We like to produce something special with a radical sensoriality. But we have to balance that with the delivery of the actives, and the skin care efficacy of the product.
The final thing is claims. We
always conduct very disruptive clinical studies and cellular studies in order to show, with great precision, the efficacy of our products.
TP: The active ingredients in your Replasty and your other top-end products…
..are they your own technology or are they sourced from a maker of raw ingredients? AG: It depends on the product. For the Replasty range, one of the hero ingredients is Pro-XylaneTM
,
which L’Oréal Research & Innovation created 25 years ago. We are still working on it a great deal. We conduct new research on skin efficacy day after day, and year after year.
Other ingredients could be
sourced from our external partners, but we have exclusivity over the actives. Other ingredients can be sourced from external partners, selected for their potency along with exclusivity.
TP: I see that some of the Replasty range has a 30% concentration of Pro-Xylane. Why so high? AG: In fact, we have launched a night cream with a 50% concentration of Pro-Xylane. Why 30% and 50%? Because we know that with higher concentration, you have higher efficacy. You also reach new potential
efficacy. New cells are activated. It’s penetrating deeper into the skin. You are also see other benefits that are not reached at lower
www.personalcaremagazine.com January 2026 PERSONAL CARE MAGAZINE
concentrations. For example, at lower concentration, you are able to reach the stratum corneum and the upper part of the epidermis. But with more concentration, you
give more information to the deeper layers of the skin. We make the jump to firming, to lifting. It is a continuum of efficacy.
TP: At the 35th IFSCC Congress in Cannes, the Helena Rubinstein satellite symposium had a
presentation on how ozone is an emerging stressor and pollutant causing detrimental skin conditions. Could you explain this? AG: As you will know, there are major air pollutants that affect the skin, like UV light and visible light. There’s also particulate matter (PM) with diameters that are 2.5 micrometres and smaller in diameter, which can carry heavy metals.
We have launched a night cream with
a 50% concentration of Pro-Xylane. We know that with higher concentration,
you have higher efficacy Audrey Gueniche, international scientific director, Helena Rubinstein
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