36 SILICONES
Dimethicone is more reasonable. As in the experiment section, it is
proposed to evaluate BRB proprietary products BRB 2020A, 2020B, and 2020C. Those proprietary blends were also checked via sensory and indeed they provide good after-feel with characters while maintaining a high degree of clarity with 2020B leading the scores in Figure 8.
Conclusion Formulation and benefits of selected silicone ingredients has been systematically explored to be incorporated into hand sanitising gels. Several silicone copolyols can achieve crystal clear thermodynamically stable hand sanitising compositions with the right viscosity and good hand after-feel. Formulation spaces has been greatly expanded to allow formulators’ creativity by adding ingredients such as fragrances and vitamin E. Those gels mitigated several sensory shortcomings of either simple or organic polyols (glycerin or propylene glycol) enhanced hand gels. This provides much needed knowledge for formulators in this area to produce better products to combat COVID-19. For formulators who are interested in more information the following literature are available (References 5-9).
PC
References 1 Ethanol topical irrigation:
www.ncbi.nlm.nih.gov › pmc › articles › PMC2596158
2 TIPA Toxicology Study:
https://journals.sagepub.com/doi/pdf/10.3109 /10915818709095489
3 WHO-recommended handrub formulations:
https://www.ncbi.nlm.nih.gov/books/NBK144054/
4 Ethanol formulation non-irritation but reduced moisturization:
https://www.ncbi.nlm.nih.gov/pubmed/ 17578437
Coated Feel Tackiness Conditioning Smoothness Figure 8: Three-way comparison: Option B, Glycerin, Glycerin PG
5 U.S. Pat. No. 9,089,129: Non-aerosol foaming alcohol hand sanitizer by Heisig, et al.
6 U.S. Pat. No. 6,723,689: example of high alcohol content sanitizers
7 U.S. Pat. No. 6,423,239: A gel product for use as a skin sanitizer having a higher alcohol content and comprising, humectants, silicones
Table 6: Sensory testing scores of hand sanitisation gels with selected BRB Silicones. Sensory Descriptives
Blank PEG-12 Dimethicone
Transparency Dry Time Residues
Moisturization Softness
Conditioning Smoothness Tackiness
Coated feel Silky Feel Whitening
Natural Skin Feel Spreading Ease
PERSONAL CARE EUROPE
10 0 0 5 3 4
10 0 0 8 0
10 10
10 3 1
10 10 8
10 0 1 7 0 6
10 PEG-10
Dimethicone 10
PEG/PPG- 18/18
Dimethicone 10
Cetyl
PEG/PPG-10/1 Dimethicone
as detackifying agents, moisturizers, and thickeners.
8
https://www.brb-international.com/uploads/ markets/brb-personal-care-brochure.pdf
9
https://www.yumpu.com/en/document/ view/10005795/formulating-hydroalcoholic- gels-with-carbopol-technical-lubrizol
TMS BRB1860 DM55 DM66 Glycerin/ PG
4 09 88 10
1 33 53 27 7 0 01 70 00 0 9 49 58 10 8
9 6 10 79 8 10 7 10 10
9 7
9 68 68 89 8 7 88 0
8
1 24 00 00 7 3 05 10 7 78 5
10 10 5 3
10 10
0 12 6 10
8
10 10
10 10
2
0 03 50 00 1 6 87 2 10
3 3
November 2020 Spreading Ease Natural Skin Feel Whitening
n Blank BRB 526 n Gly/PG Transparency
10 9 8 7 6 5 4 3 2 1 0
Silky Feel Coated Feel Tackiness Dry Time Residues Spreading Ease Natural Skin Feel Moisturisation Whitening
n Blank BRB 1860 n Gly/PG Transparency
10 9 8 7 6 5 4 3 2 1 0
Dry Time Residues
Moisturisation
Softness Conditioning Smoothness
Silky Feel Coated Feel Tackiness
Softness Conditioning Smoothness
Figure 6: Three-way comparison: Blank, BRB 526, Gly PG
Figure 7: Three-way comparison: Blank, BRB 1860, Gly PG
Transparency Spreading Ease Natural Skin Feel Whitening
10 9 8 7 6 5 4 3 2 1 0
n Glycerin Option B n Gly/PG Dry Time Residues
Moisturisation
Silky Feel
Softness
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