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40 Exclusive Agreement to Distribute Particle Measuring System Extends Biopharma Solutions


Materials characterisation company Malvern Instruments Ltd has signed an exclusive distribution agreement with Affinity Biosensors LLC which will extend the range of solutions that Malvern offers to the biopharmaceutical sector. The distribution agreement covers all geographies outside the USA and Canada. Under the terms of the agreement Malvern will distribute the Archimedes Particle Metrology system, developed and manufactured by Affinity Biosensors, through its subsidiaries in Europe and Asia. Malvern will establish a co-marketing arrangement with Affinity Biosensors in North America.


Archimedes, which won the Pittcon Editors Gold Award in 2010 and an R&D100 Award in 2010, employs a unique patented technology co-invented by the Massachusetts Institute of Technology (MIT) and Affinity Biosensors. Using the technique of Resonant Mass Measurement (RMM), Archimedes detects and counts particles and determines their mass and size with high resolution and accuracy, in small sample volumes. A key area of application is the measurement of protein aggregation in biotherapeutic formulations, which provides critical information needed to speed development and improve drug safety and efficacy


“We are very pleased to be involved with this exciting new technology and to be adding it to our growing range of solutions for biopharmaceutical researchers,” said Duncan Roberts, Business Development Director for Malvern. “Protein aggregation is a significant challenge in the development of protein-based drugs, and an area of increasing interest and potential regulation. Archimedes will sit alongside Malvern’s Zetasizer and Viscotek systems, all of which deliver complementary solutions for customers in this fast growing pharmaceutical industry sector.”


Archimedes allows precise measurement of size and mass of particles with diameters down to 50nm. Measurements are unaffected by optical or shape variations, and gentle fluidics ensure that fragile aggregates are not disrupted. The instrument can measure high viscosity samples and consumes as little as 100µl of precious protein formulation. Archimedes can accept particle concentrations up to 1x109 per ml, allowing direct study of undiluted high concentration formulations.


Archimedes can also differentiate between protein aggregates and silicone oil droplets in an injectable biopharmaceutical using buoyant mass measurement, something that no other technology can do at the submicron size scale.


MORE INFO. 114


Affordable Camera Packs for R&D Applications Introduced


FLIR Systems has introduced the affordable SC35, SC15 and SC5 camera packs for R&D applications. Thermal imaging cameras can be used for a wide variety of R&D applications. However until now access to high performance thermal imaging cameras was often the privilege of just larger R&D groups. Visualising temperatures from -40°C to +550°C, with temperature differences as small as 50mK, the new ultra- compact SC Series Camera Packs bring the advantages of research grade thermal image to the test bench of every R&D engineer.


In the R&D environment, the thermal imaging camera is just one part of the solution, of equal importance is software to analyse the thermal image. Designed with R&D engineers in mind - FLIR Tools+ software is included with every SC35, SC15 and SC5 Pack. Working seamlessly with SC Series Camera Packs - FLIR Tools+ software enables researchers to view, record and analyse thermal image data with functions such as time versus temperature plots. For experiments that require more than one camera to cover the object, or for stereoscopic applications, it is also possible to configure one SC Series Camera to be master and others to be slave(s).


The FLIR SC Series Camera Packs come standard with GigEVision™, a state-of-the-art camera interface developed using the Gigabit Ethernet communication protocol. GenIcam™ is also supported on the FLIR SCSeries Camera Packs to provide a generic programming interface for all types of cameras. Therefore regardless of interface technology (GigE Vision,Camera Link, 1394 DCAM, etc.) or features implemented, the Application Programming Interface (API) will always be the same.


MORE INFO. 115


Laborama Goes Green


On 14th and 15th March 2013 the 14th Laborama, the professional fair for laboratory professionals, will take place in Groot-Bijgaarden. Laborama is organised by UDIAS, the professional association for the laboratory sector. With nearly 110 registered exhibitors it appears that Laborama will be again the meeting point by excellence in Belgium for laboratory professionals. During this edition there will be a special focus on biotechnology. In hall 2 there will be a theme booth constructed which focuses on this discipline and where companies will show you their specific products and services.


Laborama will be investing in durability and the organiser of the trade fair will equip its booths with LED lightning. This is an important investment contributing to a cleaner environment. From now on Laborama can call itself a durable and ecologic fair. The fair is completely constructed with recyclable materials: modular booths, reusable carpet and LED lightning. The fair organiser, UDIAS, hereby wants to highlight its social commitment.


From 2nd January 2013 the pre registration for visitors at Laborama 2013 became available. Visitors can now pre-register online via www.laborama.be. Access to Laborama is free provided visitors pre-register online.


MORE INFO. 116


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