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New 1.3-Micron Core- Shell Media Delivers Superior UHPLC Performance
Labware by Diba is launching OmniSep™, a new standard in pre-packed columns for biomolecule separation and purification.
Building on Omnifit®’s existing partnership with Kinesis, OmniSep™ will be distributed
worldwide exclusively by the leading international supplier of chromatography and liquid handling consumables and equipment. With offices in the UK, USA, Germany and Australia, Kinesis is ideally positioned to support the OmniSep™ brand.
“Kinesis has proven their ability to support the Omnifit® Labware product line both in Europe
and the US,” noted Diba Industries President Todd Burt. “We’re pleased to partner with them to launch this important new offering for our chromatography customers.”
OmniSep pre-packed columns are available with IEX, HIC, SEC and Affinity media and are certified for consistency and repeatability. Most important of all for laboratory researchers, OmniSep is proven to be commercially equivalent to other leading soft-gel media.
Exclusive Distribution Partner for New OmniSep™ Packed Columns Announced Omnifit®
MORE INFO. 49
Phenomenex Inc announces the addition of 1.3- micron UHPLC columns to its Kinetex core-shell product line. With the smallest diameter in the Kinetex family, the 1.3-micron is the most efficient particle on the market, delivering measurably better performance than conventional fully porous media on UHPLC equipment. The Kinetex core-shell family now includes four particle sizes, from 1.3- to 5-micron, providing separation solutions for virtually every chromatographic application and easy method transferability from UHPLC to HPLC to preparative-scale LC.
“The Kinetex product line spans our customers’ needs, from sub-2-micron UHPLC to small-scale purification, enabling everyone to take advantage of the performance and productivity gains that core- shell technology can deliver,” commented Simon Lomas, Brand Manager for Phenomenex.
With efficiency levels over 400,000 plates per meter, the Kinetex 1.3-micron represents a dramatic advancement in LC media technology. UHPLC users can now reach previously unavailable levels of sensitivity and performance, with the added benefit of easy method transferability and scalability to any of the three other Kinetex particle sizes. While fully porous sub-2-micron columns exhibit significant band broadening due to frictional heating as flow rate increases, the Kinetex particle morphology and packing technology help to reduce these and other effects to ensure high resolution and sensitivity over an extended linear velocity.
Phenomenex core-shell products meet researchers’ need to improve results and increase productivity with their current instrumentation. By delivering significant improvements in speed and separation power over traditional fully porous columns, Kinetex columns enable chromatographers to get superior results on any LC or UHPLC platform, along with potential reductions in solvent usage.
MORE INFO. 51
New LC Column Line for Protein Separations Protea Biosciences Group, Inc announced at the ASMS Sanibel Conference the introduction of Amplus®
columns, a new line of liquid chromatography columns specifically designed for intact proteins analysis.
This new family of HPLC silica-based columns employ core shell technology combined with a specific porosity designed to facilitate proteins separation, including those with high molecular weight.
“This year the ASMS Sanibel Conference is focused on Top Down proteomics applications and we thought it was a great opportunity to introduce a new technology designed for intact protein chromatographic analysis,” stated Alessandro Baldi, PhD, Vice President and General Manager of Protea Biosciences. ‘Amplus’ technology provides scientists with high chromatographic efficiency and facilitates Top Down proteomics approach to study intact proteins with or without mass spectrometry.”
Amplus, the new brand of analytical columns, has been developed in collaboration with the Japanese firm CromaNik Technologies and it is available in different chemistries and porosities to facilitate and resolve the most difficult separations in Top Down proteomics studies.
MORE INFO. 50
New Control Driver for ELSD System Announced DataApex is pleased to announce the release of a new control driver for the Alltech®
3300 evaporative
light scattering detector (ELSD) from Grace Discovery Sciences, a business unit of W. R. Grace & Co. This driver has been officially released with Clarity Chromatography Software version 4.0.2.
“We are striving to maximise the portfolio of Clarity controlled instruments. The cooperation with a manufacturer such as with Grace is always inevitable for successful development,” commented Jan Hruby, DataApex General Manager on the driver release. Grace Discovery Sciences is a market leader in ELSD technology; further information on the Alltech®
3300 ELSD can be found at
www.discoverysciences.com. Grace is a leading global supplier providing innovative products, technologies and services that enhance the quality of life. Grace employs approximately 6,000 people in over 40 countries and had 2011 net sales of $3.2 billion.
Clarity Chromatography Software has a strong position in the chromatography data systems market. Clarity, the third generation of DataApex products, allows controlling more than 400 different instruments from the single environment and offers its users very high flexibility. Clarity is highly regarded for its intuitive approach, excellent performance, cost-effectiveness and proficient technical support. DataApex is solely focussed on chromatography software development. A strong emphasis is placed on technological innovation, visionary adoption of new laboratory standards, best practices and extensive customer support. DataApex products are sold in over 80 countries around the world. Ten chromatography instrument manufacturers privately resell labelled versions of DataApex’s software. To obtain further information about DataApex Clarity products please contact us at
clarity@dataapex.com or visit
www.dataapex.com.
MORE INFO. 52
wide-pore core shell HPLC
New UHPLC System Released
Shimadzu has introduced the Nexera X2 UHPLC system providing exceptional insights into the compounds analysed. It is perfect for routine analysis as well as applications in highly regulated environments demanding complex system setups. Compared to the predecessor Nexera system, this completely renewed Nexera X2 offers higher core performance as well as new features improving analytical efficiency in a wider range of HPLC/UHPLC applications.
The new SPD-M30A photodiode array detector provides superior stability and has been designed for ultra-high sensitive applications. It suits the analysis of trace impurities and hazardous substances in food or drugs perfectly due to its world’s highest levels of spectral resolution, sensitivity and outstanding separation. The new i-PDeA (intelligent Peak Deconvolution Analysis) function enables peak separation of non-separated peaks by extracting the peak spectra from co-eluted peaks, and quantitates them by exploiting the differences in spectra between each compound. i-PDeA enables users to visualise and detect a minor single impurity even when the impurity is co-eluted with an analyte.
Modifications applied to the pump side significantly improve Nexera X2’s stability in gradient use while reducing small air bubbles passing through the degassing unit. Additional micro reactor-based mixing devices can be selected for specific applications. A low volume quaternary option reduces the system volume in order to meet UHPLC needs while enabling a better intersystem method transfer.
The software has been intentionally adapted to meet the requirements for use in highly regulated environments. Software features controlling multiple gradients in a single system expand the system flexibility to use automated solvent blending on each pump in a binary gradient setup. Together with ultra- high speed data acquisition, software features maximise resolution on the PDA detector, ensuring peak deconvolution while squeezing maximum information out of a single analysis.
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INTERNATIONAL LABMATE - JANUARY/FEBRUARY 2013
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