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Analytical Community Rewards Centrifugal Field-Flow Fractionation System with 2012 Innovations Award
The new CF2000 Series for high-resolution separation and fractionation of nanoparticles, from Postnova Analytics, has won the prestigious GIT Innovations Award 2012 in the category ‘Analytical Instrumentation and Software’. The Postnova team are the inventors of the Field-Flow Fractionation (FFF) technique, and developed the CF2000 to be the first Centrifugal FFF system for routine use.
Dr Thorsten Klein, Founder and CEO, Postnova, said: “It is a great honour to receive this award. To be acknowledged by scientists working at the bench is particularly important for us as it shows that our innovative products are recognised as powerful practical tools for daily analysis, exactly what we designed them to be. I would like to thank the publishers at G.I.T. Verlag for sponsoring the award, the independent jury who placed the CF2000 on the shortlist and, most of all, everyone who took the time to vote for us online, at Analytica, and at Achema.”
The CF2000 is modular, allowing for a range of different detectors: Multi-Angle Light Scattering (MALS), Dynamic Light Scattering (DLS) and Refractive Index (RI), for example, to be integrated. Whatever the configuration, everything from autosampler to detector is fully controlled by the NovaFFF software platform.
Importantly, by using a centrifugal field as the controlling force for the separation, particles are separated by Dynamic Diffusion on the basis of size and density. This novel approach allows discrimination of materials that have the same particle size but different densities.
The CF2000 has a wide operation range and is able to separate smaller species, such as proteins and polymers, from larger particles in one run with high resolution. The system is ideal for nanoparticles and works up into the microparticle size range too. No special sample treatment is necessary, allowing challenging biopharmaceutical, food-cosmetics, nanomaterial and environmental samples to be characterised.
MORE INFO. 42
Headspace Sampler for GC and GCMS Serves a Wide Range of High Sensitivity Applications
Labware by Diba is launching OmniSep™, a new standard in pre-packed columns for biomolecule separation and purification. High quality agarose- and dextran-based media coupled with easy-to-use Omnifit®
Launch of Packed Columns for Biomolecule Separation and Purification Omnifit®
Labware’s market leading glass columns make preparative chromatography cost-effective, efficient and repeatable.
“Having listened to the concerns of laboratory technicians, we wanted to create a solution that was cost-effectiveaffordable and simple and most importantly, frees up precious research time,” said Scott Brown, VP Sales and Marketing. “Omnifit®
Labware is a well-known and respected
laboratory brand, in the laboratory and we felt that the time was right to extend our offering into gel-based mediaresins to enable us, to offer provide our customers with a complete, turnkey solution.
By design, OmniSep® media are proven to be commercially equivalent to other leading soft-gel
media, not ‘like’ and not ‘better than’,” noted Global Product Manager Trevor Hopkins. “Researchers should expect familiar chromatographic performance from the OmniSep™ media. Each column will be certified for consistency and repeatability.”
OmniSep™ offers columns packed with ten types of cross-linked agarose- and dextran-based media commonly used by laboratories for macromolecule separations. These soft gel media are available for a range of IEX, HIC, SEC and Affinity applications. The OmniSep™ media structure gives the adsorbent high chemical, physical and thermal stabilities, making it ideal for all stages of purification. The rigidity of the cross-linked media permits high volumetric flow rates resulting in fast separations with good resolution.
Shimadzu has launched the HS-20 gas chromatography headspace sampler for accurate analysis of an even wider range of volatile compounds with boiling points ranging from low to high.
The HS-20 heats liquid or solid samples sealed in a container to a specific temperature, and injects the volatile compounds diffusing into the gaseous phase into a GC or a GCMS.
These systems are widely used in the fields of environmental and pharmaceutical applications as well as in materials and food products analysis and forensics. The HS-20 will support these analyses particularly in testing and inspection organisations.
The unique configuration of flow lines and the oven enables the analysis of high boiling point compounds while minimising carryover.
Using the electronic cooling trap, it is also possible to concentrate the headspace gas for analysis of compounds with extremely high sensitivity.
Headspace samplers enable easy analysis of volatile compounds. They are used in various fields requiring higher reliability, such as analysis of VOCs (volatile organic compounds) in the environmental and quality control applications of pharmaceuticals whereas in food products and materials control a wide range of volatile compounds with low to high boiling points has to be detected with high sensitivity in order to provide accurate qualitative and quantitative results for numerous measurement targets.
MORE INFO. 44
OmniSep media are easy to use, and they tolerate the typical conditions of temperature, pH and chemical agents, including cleaning-in-place (CIP) reagents, routinely employed in biomolecule purification and separation processes. OmniSep™ will be distributed worldwide exclusively through Kinesis, a leading international supplier of chromatography and liquid handling consumables and equipment worldwide.
MORE INFO. 43
Launch of Expanded Integrated LC/MS Platform for Peptides Mapping and Glycans Analysis
Complementing the Expanded Biopharmaceutical Platform Solution are New Charged Surface Hybrid Particle Column and GlycoWorks Kit for Glycan Preparation. Waters Corporation have reinforced its commitment to advancing biotherapeutic characterisation technology at the Well Characterized Biotechnology Pharmaceuticals 2013 Symposium (WCBP 2013). More specifically, Waters® of its Biopharmaceutical Platform Solution with UNIFI®
have introduced an expansion , new ACQUITY UltraPerformance LC® (UPLC® )CSH130 C18 and XSelect™ HPLC CSH130 C18 columns for peptide mapping, and three GlycoWorks™ kits for glycan labelling and sample preparation.
These innovations represent Waters’ continued focus on developing targeted solutions for developers of biotherapeutics and biosimilars, as well as related contract laboratory organisations. These new products further progress routine biotherapeutic analysis, particularly for glycoproteins that require analysis of glycan modifications in addition to detailed protein and peptide level structural analysis.
Armed with more rapid and accurate glycosylation knowledge throughout the development and manufacturing process, biopharmaceutical companies can gain a greater degree of control over the critical quality attributes of their molecules. Such capabilities are in-line with increasing regulatory expectations aimed at guaranteeing safe and efficacious biotherapeutics.
MORE INFO. 45
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