12 Multi-Reflection ATR Accessory
The Pike Technologies JetStream is a unique ATR accessory that is optimised for analysis of liquids in static or dynamic modes under ambient or variable pressure conditions. The accessory design features a cylindrical ATR crystal encased in a heavy-duty stainless steel body. The crystal’s geometry has been carefully chosen to maximise its performance. The crystal generates 12 reflections along its body with throughput sufficient to perform high sensitivity measurements. JetStream’s compact design employs a pair of transfer optics directing the infrared beam to one end of the crystal. A similar pair of optics directs the beam exiting the accessory to the spectrometer’s detector. The sample enters and exits the measurement chamber via Swagelok®
ports
and completely surrounds the crystal. This assures efficient sampling and very good reproducibly. The JetStream Accessory is available for all brands of FTIR spectrometers.
Pike Technologies, established in 1989, became a primary source for spectroscopy accessories and applications worldwide. Products include attenuated total reflectance (ATR), diffuse reflectance, specular reflectance, integrating spheres, polarisation, IR microscope, beam condensers, remote sensing, and a complete line of transmission sampling accessories. Many of these products are available with optional heating and automation for increased sampling speed and productivity. Pike Technologies, Inc also offers design and consulting services for development of specialised and custom products for a wide range of spectroscopy applications. Pike products are compatible with all major brands of spectrometers.
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Spectroscopy Development Platform Updated with New Features
New Article on Bioanalysis of Dermorphin in Equine Urine with VIP Heated-ESI Technology
An article examining the difficult bioanalysis of thermally labile peptides performed on the recently launched Bruker EVOQ™ liquid chromatography mass spectrometer (LC-MS/MS) is described. The article entitled ‘Bioanalysis of Dermorphin, an Opioid Peptide in Equine Urine: Benefit of the VIP Heated-ESI Technology for the Quantitative Analysis of Thermally Labile Molecules’ from the Bruker CAM division, has been published in the November/December issue of Chromatography Today. Authored by product specialists from Bruker’s liquid chromatography mass spectrometry group the article explores the quantification of Dermorphin in equine urine using solid phase extraction cleanup. The linear dynamic range of the assay was 0.5- 1000ng/mL and this was easily obtained on the EVOQ Elite™ LC-TQ.
Dermorphin is a naturally occurring hepta-peptide derived from the skin secretions of South American frogs (Phyllomedusa sauvegei). It is a unique analgesic 30-40 times stronger than morphine, containing D-alanine making it highly resistant to protease degradation, thus making it a very effective analgesic. Dermorphin use as a horse racing performance enhancing drug came to the public fore as an illicit drug, when it was found to be used to push racehorse performance beyond natural limits, often injuring the horse. Dermorphin has since been reclassified as a Class 1 prohibited substance as decreed by the American Association of Racing Commissioners International Model Rules and this practice has largely been adopted worldwide.
Ocean Optics has released an update to its OmniDriver Spectroscopy Development Platform. The platform-neutral Java based OmniDriver Version 2.20 provides a simple interface for programming of USB spectrometers, accessories and devices in optical sensing systems, and is available with an optional set of spectral processing math algorithms. New features have improved the platform’s high-speed data acquisition, spectral processing, data analysis, data visualisation and data transfer options.
With native libraries included for a variety of Linux, Macintosh and Windows operating systems, OmniDriver users can develop robust control applications without knowing Java; the wrapper libraries provide an interface for most languages to link against. The OmniDriver’s platform- and spectrometer- independent programming means the same code works with any Ocean Optics USB spectrometer. With Version 2.20’s new ‘SpeedTest’ feature, users can determine the maximum performance possible for a spectrometer model on the Windows operating system.
Also, OmniDriver Version 2.20 has more robust algorithms for photometry and colourimetry. This is an especially useful feature when measuring samples with sharp peaks, such as in narrowband sources like those used in laser projection systems.
For OEMs, two new command line parameters have been added to the installer for customisation of the company and driver name. Drivers for three additional Ocean Optics’ devices have now been certified by Windows Hardware Quality Labs, meaning drivers for most of the company’s devices will install automatically when connected to a Windows 7 PC.
The OmniDriver’s wrapper libraries include Dynamic Link Library (Windows), Shared Object (Linux) and a .NET object (Windows). The software is compatible with a variety of operating systems: Windows XP, Vista, Windows 7, 64-bit versions of XP, Vista, and Windows 7; Mac OSX 10.3 or later; plus many Linux x86 distributions (Kernel 2.4.20 and libusb 0.1.10 or later are required).
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The quantification of Dermorphin in equine urine has been a challenge on several fronts because of the complex matrix of equine urine, a lack of stable labelled internal standards and the peptide is thermally labile during LC nebulisation. Crucially, the EVOQ’s novel vacuum insulated probe heated electrospray ionisation (VIP-HESI) technology delivers the greatest heat at the tip of the ESI probe at the point of ionisation, protecting it from over heating and degradation. By efficiently ionising thermally labile molecules, such as peptides and metabolites, at conventional flow rates the VIP-HESI enables the analysis of real-world samples. Even with no isotope labelled industry standard the EVOQ accurately quantified dermorphin in equine urine between the ranges of 0.1-1000ng/mL.
MORE INFO. 27
Laboratory Reagents and Fine Chemicals
Loba Chemie was a venture started over 35 years ago to deal in Biochemical’ s and Reagents for life science research and other specialty chemicals. Loba Chemie today is one of the forerunners in the Indian chemical industry. In a matter of years Loba Chemie through its teamwork and efficiency, not forgetting its superior products, has been able to establish a strong market share throughout India.
At present Loba Chemie is among the top 5 chemical companies in India. With a state-of-the-art manufacturing and testing facility providing a range of over 4500 products to meet international customer demand, the range of products include: reagents ACS/GR/AR, fine chemicals, HPLC solvents, inorganic salts, biological stains and dyes, indicators, buffers, dry solvents, CVS, ion pairing, essential oils, perchloric acids, bromine, AAS and ICP standards, BP/USP/Ph. Eur and more.
Loba Chemie is a global supplier for its high quality products and has been able to develop its market share with customer satisfaction and its quality products in many corners of the world. At present Loba Chemie is doing business with over 80 countries, to name a few UK, Germany, Belgium, France, USA, Australia, Brazil, Argentina, Egypt, Malaysia, Thailand, Indonesia, and many more. Loba is also a provider for Bulk Packs and OEM Services.
MORE INFO. 29
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sales@intlabmate.com INTERNATIONAL LABMATE - JANUARY/FEBRUARY 2013
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