Sample Preparation & Processing Next Generation High-Speed Centrifuge Simplifies Performance


The new Thermo Scientific Sorvall LYNX superspeed centrifuge series incorporates exclusive innovations – Auto-Lock rotor exchange and Auto-ID instant rotor identification – to deliver productivity, safety and reliability and maximise everyday centrifuge use in shared laboratory settings.


The Thermo Scientific Sorvall LYNX centrifuge features a 100,000 x g top speed performance and supports high-throughput sample processing from 50mL conical tubes and microplates to 1L bottles, up to a six-litre capacity, meeting the evolving needs of academic research and production facilities alike. Run set- up is easy with the intuitive touchscreen interface featuring a bright, highly visible and durable display, while on-board video tutorials and access controls, such as user login with password protection, provide advanced training and programming options.


“Today’s researchers require centrifuge performance that is simplified, to accommodate the reality that labs have multiple users with different experience levels and a variety of processing requirements,” said Maurizio Merli, Global Product Director, Centrifugation, Thermo Fisher Scientific. “Our new Sorvall LYNX superspeed centrifuges dramatically simplify high-speed centrifuges while increasing user safety and peace of mind. We accomplish this with breakthrough technology advancements, such as the Auto-Lock rotor exchange, Auto-ID instant rotor identification and carbon fibre rotors.”


The Sorvall® LYNX superspeed centrifuge series features built-in safety and rotor technology innovations that shorten run set-up time and increase security, including: secure, push-button Auto-Lock®


rotor exchange in less than 3 seconds, ensures that the rotor is automatically and securely locked and will not loosen


during a run, enhancing user confidence; Auto-ID® instant rotor identification recognises a rotor when secured in the chamber, improving safety, saving time, and protecting the integrity of your samples; lightweight, corrosion-resistant Fiberlite®


carbon fibre rotors, including the new Fiberlite LEX designs, improve


ergonomics and performance; rotor lids for microbiological containment, certified by the Public Health Laboratory Service, Porton Down, UK; latest in global safety compliance without the need to bold down the instrument to the floor, simplifying installation and providing flexibility to relocate.


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High Throughput Sample Clean-up


Turnkey Workstation Offers Variable Volume DNA Isolation HSM workstation provides reliable walkaway


extraction of gDNA from large volume blood samples using Promega’s proven ReliaPrep™ Large Volume HT gDNA Isolation System.


The Freedom EVO - HSM workstation is designed to streamline biobanking workflows, offering intelligent one-tube gDNA extraction from up to 32 samples in less than four hours. The compact system is controlled by Tecan’s intuitive TouchTools™ touchscreen interface, and features pre-installed protocols that have been rigorously tested and verified by Promega. Using the platform’s liquid level detection function, the system is able to automatically calculate the reagent volumes for each sample, ensuring efficient walkaway extraction of high quality DNA from 1-10ml of blood and meeting the specific requirements of next generation sequencing methods.


Caroline Huber, Senior Market Manager at Tecan, commented: “We are very pleased to be working in close collaboration with Promega. Tecan’s expertise in laboratory automation is a great fit with Promega’s genomics tools and reagents, creating a truly unique solution for biobanking applications, backed by the technical support and experience of both companies.”


The MicroluteTM SPE sample preparation system from


Porvair Sciences provides a faster, trouble-free alternative to cartridges for high throughput sample


clean-up. Handling samples as small as 150µl the Microlute™ SPE sample preparation system helps you increase your assay sensitivity by providing pre- injection clean-up and concentration you can trust. As a complete package, including filter plate, collection plate, waste tray and manifold, the Microlute™ SPE sample preparation system offers all the advantages of automated and high throughput SPE sample preparation in a convenient microplate format capable of rapidly processing 96 samples in one go repeatedly and precisely.


Constructed from a single piece of moulded ultra pure polypropylene, the Microlute™ plate will not bend or distort because individual SPE cartridges do not have to be repeatedly plugged in and out. Using a proprietary sorbent slurry loading technique, Porvair has eliminated the channelling effects that often limit the performance of dry powder loaded SPE columns. Each well on a Microlute™ plate has an individual drain spout ensuring 100% sample transfer and zero crossover contamination. To recover dried or concentrated sample the Microlute™ SPE sample preparation system may be coupled to a Porvair MiniVap sample concentrator.


Microlute plates are available with a choice of sorbent and filter, and sample collection plates in a selection of well volumes (350µl, 1ml or 2ml), to optimally match your sample clean-up requirements.


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“This really is an ideal set up for laboratories,” added Promega’s Genomics Marketing Director Tim Sheehy. “As a reagent solutions provider, we know that sample requirements can change from one project to another. The efficiency and reliability of Tecan’s Freedom EVO system make it the ideal platform for integrating the ReliaPrep Large Volume HT gDNA Isolation System, offering customers the flexibility to handle a wide range of sample types and volumes.”


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Tecan and Promega have developed a turnkey workstation for fully automated extraction of gDNA from whole blood samples. Designed to meet the needs of biobanks and high throughput genomic laboratories, the Freedom EVO®


New Standards Set in Ultrafiltration


Sartorius is introducing a new generation of ultrafiltration devices to the market. The disposable Vivaspin Turbo 15 is optimally suited for protein, virus or nanoparticle concentration as well as desalting, dialysis and buffer exchange. It is available in a range of volumes from 4 to 15ml and permits easy and complete recovery of the concentrate, yet is the fastest ultrafiltration device on the market.


With Vivaspin Turbo 15, lab technicians can concentrate biological samples within 10 to 30 minutes and obtain macromolecular recoveries of more than 95%. In a single spin, 15ml solutions can be concentrated up to 150 times.


High flow rates are achieved due to the twin vertical membranes, which minimise protein polarisation and subsequent fouling of the membrane. The optimised design and sleek internal profile of Vivaspin Turbo 15 ensures maximum process speeds down to the last few microlitres.


The 100-microlitre dead stop pocket is easy to access with standard 200-microliter pipette tips due to the patent pending angular design of Vivaspin Turbo 15. It eliminates the risk of the sample running to dryness while allowing highest recovery of the concentrate.


The use of highly chemically resistant plastic materials, such as polystyrene and polypropylene, guarantee a stable shelf life, even in humid environments. Polyethersulphone membranes are preferred for their low fouling characteristics, exceptional flux and broad pH compatibility. The combination of polyethersulphone, polystyrene and polypropylene enables Vivaspin Turbo 15 units to be readily sterilised and depyrogenated.


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