36 MARINE INGREDIENTS


Global reinforcement of skin architecture vs. bakuchiol The principal in vivo trial involved 54 women (aged 45-60 y.o.) presenting with visible signs of ageing and a loss of skin architecture. The study compared the marine active at 1% to 0.5% bakuchiol. ■ Short-term efficacy (14 days): The kelp-derived active demonstrated a performance comparable or better to the benchmark within just two weeks, establishing a robust baseline for structural reinforcement. Instrumental measurements revealed that improvement in skin architecture was 8.6 times higher than bakuchiol during this initial phase. ■ Long-term consolidation (56 days): While traditional inhibitory approaches may reach a plateau, the mechanism of the kelp-derived active provides a cumulative effect. By day 56, skin tonicity improved by +15% vs. placebo, performing 2.8 times better than the bakuchiol benchmark.


Global skin appearance improvement Beyond structural metrics, the impact on skin quality was evaluated through visual and qualitative analysis. Advanced 3D topographic mapping captured a 4.7% refinement of the skin grain, leading to a smoothing effect 7.4 times superior to the benchmark at day 56 (Figure 3). Qualitative feedback from the volunteers


supported these results: 70% of participants perceived firmer skin, and 63% reported a visibly improved global skin appearance. Volunteers described their skin as looking less tired and more resilient. This confirms the active’s ability to deliver a comprehensive improvement in skin surface quality, satisfying consumer expectations for both immediate and long-term visible results.


Environmental stewardship In an era of science-based beauty, high performance must be matched by a commitment to environmental responsibility. By producing biomass in a closed, fully contained system, Celebrity biotechnology protects marine biodiversity. To provide transparency, a comprehensive Life


Cycle Assessment (LCA) was conducted based on 16 standardized environmental indicators (ISO 14040/14044). At equal performance, the precision-engineered active (INCI: Water - Propanediol - Macrocystis pyrifera (Kelp) extract) has a better overall environmental impact than a classical extract of Macrocystis pyrifera. This commitment to quantified data allows brands to share a story of true environmental stewardship with their consumers.


Versatility of rare marine resources: Broadening the application The mastery of rare macroalgae culture is not limited to a single application. This expertise serves as a gateway to unlocking diverse marine potentials for various skin concerns. Celebrity blue biotechnology serves as a gateway to unlocking diverse marine potentials. For instance, a specific active ingredient


PERSONAL CARE MAGAZINE July 2026


D0


D56


Rough skin


SKIN SMOOTHNESS SCORING


derived from the rare life stage of Undaria pinnatifida (Caprylic/Capric Triglyceride - Undaria Pinnatifida Extract), has the ability to provide an immediate and long-lasting antioxidant effect on cells and a mitochondrial protection. Similarly, another biotech-derived ingredient


(Water - Butylene Glycol - Hydrolyzed Rhodophyceae Extract) demonstrates the value of this technology for oily skin exposed to urban stress. It is sourced from the rare red alga Acrochaetium moniliforme, which is notoriously difficult to collect consistently in the wild because of its microscopic size and scattered distribution. Biotechnology allows for the industrial-


scale production of this biomass to provide a powerful dermopurifying effect. By regulating sebum production by 34% and protecting immune sentinel cells from urban dust and ozone, it provides a specialized solution for maintaining a purified complexion despite the stresses of modern city life.


Conclusion As the beauty industry continues its transition toward high-performance, ingredient-driven models, blue biotechnology provides the necessary bridge between nature’s rare potential and industrial requirements for efficacy and sustainability. Macro’Age exemplifies this new generation of actives: it reinforces skin architecture, matches or outperforms traditional benchmarks like retinol and bakuchiol, and is produced with total respect for marine ecosystems. By harnessing the power of rare macroalgae


Smoother skin Figure 3: Mapping of skin smoothness variation thanks to the kelp-derived active between D0 and D56


through Celebrity blue biotechnology, the industry is entering a new era where science not only addresses the visible signs of ageing but supports the skin’s structural health through precision, transparency, and responsibility.


References 1. Kantar Profiles/Mintel (November 2023). Ingredients in Beauty – US – 2023. Consumer Research.


2. Mintel (February 2024). Ingredients in Beauty: Hero Ingredients in Skincare. US/UK Report.


3. Mukherjee S et al. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical Interventions in Aging. 2006; 1(4), 327-348


4. López-Otín C et al. Hallmarks of aging: An expanding universe. Cell. 2023; 186(2), 243-278


5. Krutmann J et al. The skin aging exposome. Journal of Dermatological Science. 2017; 85(3), 152-161


6. Coppé JP et al. The senescence-associated secretory phenotype. Annual Review of Pathology. 2010; 5, 99-118


7. Franceschi C et al. Inflamm-aging: An evolutionary perspective. Annals of the New York Academy of Sciences. 2000; 908(1), 244-254


8. Varani J et al. Decreased collagen production in aged skin. The American Journal of Pathology. 2006; 168(6), 1861-1868


9. Fitton JH et al. Therapies from Fucoidan. Marine Drugs. 2011; Sep 30;9(10):1731–1760


10. Brandner JM et al. Tight junction proteins in the skin. Skin Pharmacol Physiol. 2006; 19 (2): 71–77


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