Pumps, Valves & Liquid Handling Crevice-Free Valves for Aseptic Applications
Eliminating areas in process systems which may increase the potential for bacteria growth, such as traps and crevices, is an important requirement for control valves used in aseptic applications. Control valve specialists Samson Controls offer a range of products incorporating these features which are manufactured to quality assurance systems certified to ISO 9001, whilst also meeting stringent FDA requirements.
For example, their type 3347 control valve has polished steel parts to ensure the highest purity for the process medium, special PTFE bushing along with an additional steam line connection that is used to meet very stringent purity requirements preventing bacteria from spreading at the actuator stem guide.
Another example is the Type 3249 valve which is equipped with an EPDM diaphragm and a back-up safety packing box to ensure total protection against bacteria spreading and prevent product leakage. These sealing systems, which constitute the main components of the valve construction, have been thoroughly developed and designed to ensure a long and reliable service life.
Process applications which involve pasty, fibrous or highly viscous products are best controlled by Samson’s Type 3345 cavity-free valve body which features a diaphragm available in either rubber, nitrile, butyl or PTFE which acts both as a seal and a valve plug.
These valves can be easily installed into the process line as they are available with various connections including hygienic couplings, flanges and clamp connections according to ISO 2852 and welding ends.
28501pr@reply-direct.com Save Space and Costs with Robotic Tip Refi lls
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Using automated liquid handling workstations facilitates high throughput sample processing, but can mean that a very large volume of disposable robotic tips are used. Using a tip refill system minimises the environmental and financial impact this has.
New HDI Solenoid Valve is Lighter and Smaller
EcoPac®, now available from Alpha Laboratories, is a range of robotic tip refills that are fully compatible with the Biomek® and Multimek® Workstations. This system utilises environmentally friendly refillable racks and refill stacks of 5 x 96 robotic tips, designed to fit Beckman instruments using the AP96 liquid handling head. The sturdy, specially designed refillable racks withstand the extreme forces exerted upon them by automated liquid handling workstations. They are supplied with a full tray of 96 tips and when empty it is quick and easy to reload them using the EcoPac refill stack.
The stacked tip refills save on space in the laboratory and create much less plastic waste than individual racks. Ideal for high usage laboratories, they also offer attractive cost savings compared to ready racked tips.
EcoPac tips give complete peace of mind performance. They are made from 100% virgin polypropylene and are metal- free. They are certified free from DNA, DNase, RNase and PCR inhibitors. Sterile tips are also tested for the presence of endotoxins. Their compatibility with your robot is assured as EcoPac tips are subjected to rigorous physical testing. Each batch is checked for correct functionality using the original manufacturers’ robots so you are assured of a trouble-free transition when switching to these tips. There is no need to set up new tips in the instrument software. Just select your usual tip volume from the predefined list.
Ecopac tips refills are available with 35% discount until 30th April 2014.
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A new ultra-miniature, high density interface (HDI) solenoid valve for OEM, laboratory, scientific and medical device applications is the latest example of excellence in miniature engineering from Lee Products. This new ‘plug-in’ style valve features a 2-port normally closed design and offers similar performance characteristics to Lee’s traditional 3-port HDI design, but in a smaller, lighter package.
The constant demands placed upon designers and machine builders to produce reliable and innovative products which are smaller and lighter are being met, thanks in part, to the Lee Companies’ ability to continue to redefine miniature fluidics. For example, this new HDI solenoid valve weighs less than 2.5 grams, has an overall length of 27.2mm and a diameter of 7.1mm.
The valve is available in options which provide a flow capacity (on air) from 4.4 SLPM @ 10 psid, with a Cv = 0.013, up to 14.6 SLPM with a Cv = 0.044) @ 10 psid. They have a low internal volume of 28 µL, an operating pressure range of 10 psi differential with inlet pressures from vacuum to 45 psig and an operating temperature range from 40ºF up to 120ºF.
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Low-Volume Dispenser for DMSO Back-fi lling used by Leading Biopharmaceutical Company
Redd&Whyte have announced its Preddator system has been integrated in an assay workcell by AstraZeneca, to meet a generic high throughput nano-litre dispensing application. Using the Preddator system, the assay run time has been significantly reduced, while maintaining the dispensing consistency and flexibility of the original workcell.
Scientists in the Oncology Group at AstraZeneca integrated the Preddator system as an additional dispensing module to complement a Labcyte ECHO 555 acoustic reformatter in a high throughput cell-based screening workcell. It uses the nano-litre dispensing platform across over 250 plates in 384-well format to DMSO backfill volumes ranging between 20 and 100nL over ~36 hrs per batch in each run. The main function of the Preddator system is to carry out the DMSO backfill step to maintain a constant level of DMSO across all assay wells.
John Vincent, Senior Research Scientist in Oncology at AstraZeneca commented: “It can take us around 36 hours to run an assay. We knew if we could speed up the workflow by having an efficient nano-litre dispenser to carry out the DMSO back- filling separately, we could improve the consistency of our compound dosing. This would make a significant saving of stock compounds as a result of requiring fewer stock plates and a shorter overall run time. The Preddator allows us to do this.”
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