52 SKIN CARE Skin elasticity around the neck area 6 4
*** +2%
2 0 -2 -4 -6 Weeks 2 Weeks 4
Figure 4: Changes in skin elasticity (R2) versus day 0 (D0) as assessed by Cutometer, MPA580 at defined sites on the neck area
CR at defined sites. In all cases, a significant and noticeable reduction in these lines was observed after two weeks with more pronounced changes recorded after four weeks: ■ Forehead – volume of wrinkles decreased 7% in two weeks and 12% in four weeks. Number of wrinkles decreased 25% in two weeks and 28% in four weeks. ■ Under the eye – volume of wrinkles decreased 7% in two weeks and 10% in four weeks. Number of wrinkles decreased 30% in two weeks and 32% in four weeks. ■ Crow’s feet – volume of lines decreased 6% in two weeks and 9% in four weeks. Number decreased 29% in two weeks and 31% in four weeks. Images taken with Primos CR also showed
a visible change in the number and volume of crow’s feet (Figure 3).
Beyond facial benefits Changes in skin elasticity and firmness on the neck compared to day 0 were assessed using a Cutometer MPA580. As shown in Figure 4 and 5, the beauty complex achieved significant improvements versus the placebo. Skin elasticity on the neck increased 2% in
two weeks and 5% in four weeks (Figure 4). For skin firmness on the neck, an 8% improvement was recorded after two weeks and a 12% improvement after four weeks (Figure 5).
UNTREATED DAY 0 Day 0
Placebo ■ 3% REGU® -AGE CB ■ ***
+5%
12 10 8 6 4 2 0
Weeks 2 Skin firmness around the neck area
Placebo ■ 3% REGU® -AGE CB ■ +***
12% +8% ***
Weeks 4
Figure 5: (i) Changes in skin elasticity (R2) versus day 0 (D0) as assessed by Cutometer, MPA580 at defined sites on the neck area
A visible reduction in neck lines in two weeks Changes in the length and number of neck lines compared to day 0 were evaluated by Primos CR. Based on these assessments, the length of neck lines reduced 22% in two weeks, and up to 42% in four weeks. The number of neck lines reduced by 15% in two weeks, and up to 34% in four weeks. Images taken by Antera 3D reflected these
changes, showing a visible reduction in neck lines after two weeks and an even more pronounced improvement after four weeks (Figure 6).
Skin looks healthier in two weeks After 14 days of applying either the beauty complex or the placebo formulation, all study participants completed a qualitative questionnaire covering six criteria. The feedback they provided reflected and further supported the in vivo observations, with a higher number of subjects who had used the formulation with 3% of the beauty complex responding positively compared to subjects in the placebo group. More volunteers in the active formulation
group reported that after two weeks of use, lines and wrinkles in the eye area looked smoother, dark circles under their eyes had reduced, their eyelids appeared more lifted, and their skin looked less saggy with more defined facial contours. Noticeably more respondents
3% ACTIVE FORMULATION Week 2
in this group also agreed that their skin looked healthier after two weeks of use.
Conclusion To keep their skin looking its best throughout life, a growing number of consumers are embracing holistic approaches to beauty and seeking out products and ingredients that support their skin health. However, maturing skin can have multiple needs, so ingredients that can fulfil various functions are required. By coupling the power of natural peptides
derived from two superfoods with a skin- identical superoxide dismutase, we have developed REGU-AGE CB, a clean beauty complex that works on multiple skin processes. In targeting these processes, this complex can help address multiple visible signs of skin ageing to promote healthy looking skin. Holistic beauty may start with individual
skin health and an individual sense of wellbeing, but it also extends beyond the self to consider the health and wellbeing of the planet. This means opting for more sustainable beauty products. For consumers looking for the reassurance
of a clean, sustainably produced skin care ingredient that can rejuvenate and support skin’s health and resilience – helping to contribute to a general sense of wellbeing – this beauty complex offers a genuinely holistic solution.
3% ACTIVE FORMULATION Week 4
PC
Figure 6: Neck lines changes. Images of a selected subject taken by Antera 3D PERSONAL CARE January 2025
www.personalcaremagazine.com
Delta D0 (%)
Delta D0 (%)
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76
