Laboratory Products 29 iPS-Cell Based Cell Therapies for Genetic Skin Disease
AMSBIO has published an interview with Professor Marius Wernig from Stanford University, Pathology Stem Cell Institute that discusses what could be the world’s fi rst widely applicable curative treatment for Epidermolysis Bullosa (EB). This rare genetic disease causes chronic and incredibly painful skin wounds that often lead to an aggressive form of skin cancer and eventual death.
While various cell-therapy approaches have been attempted, Professor Wernig and collaborators identifi ed the need for induced pluripotent stem cells (iPSCs), and how they could become used to treat EB in a more effi cient, applicable, and commercially viable manner.
In the past, the only way Professor Wernig’s research group could grow iPSCs cells with a normal karyotype over longer periods of time was on mouse feeder cells with serum. This combination of mouse cell co-culture and undefi ned bovine serum set was not a suitable methodology as it was almost impossible to perform in compliance with FDA safety standards.
Professor Wernig describes how StemFit® Basic03 clinical grade stem cell culture medium, available from AMSBIO has allowed his
research group to safely expand their cells using an FDA compliant protocol. While there are still hurdles to climb before a cure for EB is fully realised, using StemFit®
Basic03 has solved the challenge of reproducibly growing clinical grade iPSC’s. Read the full interview:
ilmt.co/PL/Blpv Completely free of animal- and human-derived components StemFit® feeder-free conditions during the reprogramming, expansion, and differentiation phases of stem cell culture. StemFit®
volume consumption to offer cost effective colony expansion when compared to leading competitors. More information online:
ilmt.co/PL/K2B3
58699pr@reply-direct.com
Basic03 provides highly stable and reproducible culture condition for Induced Pluripotent Stem and Embryonic Stem cells under Basic03 combines high colony forming effi ciency with lower than standard media
Sustainable Tubes from Cooking Oil Waste
Eppendorf is no longer only focusing only on the development of new products, but also on new manufacturing materials. In line with the ‘Reduce, Reuse, Recycle’ concept, the main goal is to produce polymer products in a much more sustainable way without compromising the guaranteed product quality and performance needed in increasingly demanding research.
The new generation of tubes ‘Eppendorf Tubes® BioBased’ is made from 90% ‘bio-circular’, renewable-based feedstook (recycled e.g. from food oil wastes and residues) plus 10% fossil-based feedstock. Thus, these tubes in the sizes 5.0 mL, 15 mL, 25 mL and 50 mL with screw cap are made of certifi ed polypropylene based on renewable, recycled raw materials and are called ‘BioBased’.
’ with ‘ACT Certifi cates’ (Accountability, Consistency, Transparency). More information online:
ilmt.co/PL/M2aV
58641pr@reply-direct.com
The Consumable production centre in Oldenburg/Germany meets the requirements of the ISCC PLUS (International Sustainability & Carbon Certifi cation) certifi cation system. Additionally, sustainability of the tubes is certifi ed by ‘My Green Lab®
Leading International Trade Fair
DÜSSELDORF, GERMANY 14–17 NOVEMBER 2022 Member of
New Hammer Mill Produces Fine Particles with High Throughput
Retsch has developed the new Hammer Mill HM 200 for size reduction of hard, brittle, tough and fi brous sample materials. Particles sized up to 100 mm can be pulverised to a fi nal fi neness of 0.8 mm and less.
Features like rugged design, easy handling and quick cleaning make the HM 200 equally suitable for use in laboratories or pilot plants.
The mill can be used for batchwise or continuous operation and offers a high sample throughput of up to 1500 kg per hour.
The achievable grind size depends on the sample properties and is defi ned by the aperture size of the sieve used. A variety of hoppers and collecting vessels allows for easy adaptation to application requirements.
Watch the video:
ilmt.co/PL/lrwD More information online:
ilmt.co/PL/G2zE
58902pr@reply-direct.com
Dive into the latest research
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