8 Stainless Steel Tubing Cutter Simple High Performance Preparative HPLC
The Teledyne ISCO ACCQPrep HP150 was developed and designed with the ease of a Flash system in mind. It does not follow the traditional path of an analytical system, but rather this system has been designed to be intuitive and easy-to-use.
The ACCQPrep HP150 eliminates the unnecessary and complex integration parameters found in many of the HPLC systems in today’s market. Teledyne ISCO’s PeakTrak® currently drives their CombiFlash®
software, which product line, is the basis for controlling the ACCQPrep
HP150. By using this software, the need for a standalone PC is eliminated. This results in a smaller, more compact unit with an integrated touch screen interface.
Properly cutting stainless steel tubing for HPLC can be very challenging.
This wheel type cutter from MicroSolv Technology Corporation should be used to cut stainless-steel tubing used in non-critical connections. The wheel cutter is meant to score the metal tubing to break it. This ensures you will not close the inner diameter of the tube.
This cutter has a screw which is tightened to secure the tubing and can be adjusted for a range of different tubing diameters; 1/32” to 1/4”. Replacement cutter wheels are available to make sure your cutter is always kept sharp. Great addition to any service representative’s tool kit.
More information online:
ilmt.co/PL/6lKm 58883pr@reply-direct.com
Enjoy the confidence associated with Teledyne ISCO’s active solvent and waste level monitoring which reduces the risk of solvent spills. In addition, all sample and collection racks are RFID coded eliminating the potential of missed tubes.
An exciting feature of the ACCQPrep HP150 is the Focus Gradient Generator. When activated, the user is prompted to run a preset scouting gradient then they select the target peak for purification and the focused gradient is automatically programmed into the system.
Standard features include: flow rates from 1 to 150 mL/min allow development of Prep methods directly on the system without the need for pump head changes; operating pressure up to 6000 psi; choice of UV or UV-Vis plus ELSD and MS options.
More information online:
ilmt.co/PL/5zLg 57869pr@reply-direct.com
Chromatography Column Packs Support Protein Purification Workflows
Bio-Rad Laboratories, Inc has launched EconoFit Low-Pressure Prepacked Chromatography Column Packs to support resin screening experiments in the development of protein purification workflows.
New Low Volume Air Sampler for PFAS Analysis
Bio-Rad’s range of EconoFit Columns provides a wide selection of resins in a prepacked format, allowing customers to simply screen resins and select the optimal chemistry for different target molecules. The new packs include mixed-mode, cation, and anion exchange resin columns, as well as a pack designed for His-tag protein purification. The convenient, easy-to- use and disposable column format is fully compatible with Bio-Rad’s NGC Chromatography Systems and other commonly used chromatography systems. Columns are available in 1 ml and 5 ml sizes.
“Similar resins can give different results for different target molecules, and with Bio-Rad’s EconoFit Column Packs our customers can easily perform resin scouting to identify the one which yields the best outcome for their chromatography application,” said Ertan Ozyamak, PhD, Bio-Rad Global Product Manager for lab-scale chromatography products. “Our columns deliver run-to-run uniformity to support preparative scale purifications and/or method development for new target proteins, as well as to improve existing workflows.”
More information online:
ilmt.co/PL/VEkd 58544pr@reply-direct.com
The FM4 from GL Sciences BV is an air sampler developed for sampling per- and polyfluoroalkyl substances (PFAS) in air. The FM4 design is a groundbreaking approach, which enables the simultaneous collection of particulate and gaseous PFAS in air.
In conventional collection methods based on filtration, accurate measurement is often difficult. Gaseous PFAS may be adsorbed on particles collected on the filter surface. Additionally, a gaseous PFAS may change to its non-volatile form during sampling. To solve these limitations, the FM4 was designed in such way that it minimises the contact between particles and gas and three types of adsorbents, which enable simultaneous collection of ionic and neutral/volatile PFAS.
The collected PFAS is eluted with organic solvents and quantified by gas chromatography-tandem mass spectrometry (GC-MS/MS) and liquid chromatography- tandem mass spectrometry (LC-MS/MS). Conventional activated carbons typically contain complicated pores. They have been used as adsorbents for PFAS. However, the complete elution of adsorbed PFAS is difficult to achieve. Therefore, a new functional activated carbon adsorbent (GAIAC™) was developed, which was used as the gas-type adsorbent. GAIAC™ is an innovative sorbent that is composed of synthetic resin fibre with optimised pore and surface activity, which enable the collection and elution of PFAS.
The FM4 Air Sampler was tested with a wide range of PFAS and achieved excellent recovery rates. It is lightweight and compact, easy to carry and, with its very small installation footprint, easy to deploy.
More information online:
ilmt.co/PL/QyOW 57947pr@reply-direct.com
New Application-Specific LC System
Thermo Fisher Scientific, has launched a new application-specific liquid chromatography (LC) system for biopharmaceutical laboratories to precisely generate high-purity products or for the isolation of contaminants.
The new Vanquish Analytical Purification LC system combines the separation power of analytical LC with precise fractionation to generate high-purity products or for the isolation of contaminants. Moreover, with the introduction of the new integrated Vanquish Fraction Collector, a wide application range is covered, giving all users precision in purification across their whole analytical workflow.
Biopharma laboratories can now accurately fractionate with high recovery and low carry-over, with additional automation features that will allow researchers to focus on success in their process results instead of handling the tool. “We have two Vanquish Fraction Collectors and are running them 24/7 right now. No matter the fraction size, it is fractionated and afterwards reanalysed. The team is thrilled, and these fraction collectors are running robustly with no errors,” said Dr Alexander Schwenger, Senior Manager Analytical Development for CureVac AG, Germany.
“Biopharmaceutical laboratories working at the forefront of new drug development require detailed characterisation of impurities. The superior user experience and separation performance of our award-winning Vanquish LC product line, with the addition of the new Vanquish Fraction Collector, enable researchers to isolate and purify compounds right after their analytical separation,” said Kent Davidson, Vice President and General Manager, High Performance Chromatography Solutions, Thermo Fisher Scientific. “With our broad range of high-quality chromatographic consumables, our customers can be confident that sample integrity will be preserved throughout their analytical workflow. Our products can dramatically accelerate the science to get new life-saving drugs to the patient.”
More information online:
ilmt.co/PL/JpZY 58975pr@reply-direct.com
INTERNATIONAL LABMATE - NOVEMBER 2022
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