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Mass Spectrometry & Spectroscopy 25 ICP Autosampler Supports Closed Sample Tubes


HTA is proud to announce the release of HT1200I, the fi rst and only ICP autosampler featuring support for closed sample tubes. The support to sealed samples and reagent tubes offers the defi nitive solution to corrosion and bad smell that represent very common issues when working with ICP reagents. The usage of sealed tubes helps to reduce the amount of chemical vapours in the environment: that positive effect considerably improves the quality of lab air and increases also the lifetime of any object that could be affected by corrosion phenomena. Furthermore, the support of sealed sample/solvent tubes allows to avoid the purchase of autosampler enclosures that are bulky and imply an important extra-cost.


HT1200I represents the ideal solution for high throughput labs; its layout includes three sample racks for a remarkable total capacity: up to 180x10ml sample tubes, plus 9x50ml solvent vessels can be accommodated within HT1200I carousel. Conventional tube racks are supported to accommodate a wide range of standard sample tubes, but it doesn’t end there either. For maximum fl exibility, custom racks can in fact be integrated to support even custom sample vessels and mixed rack confi guration can be included to fi t any need.


High capacity generally goes hand in hand with a bulky footprint. Forget this juxtaposition with HT1200I: its unique design minimises bench space occupation making HT1200I the autosampler that features the highest sample capacity per bench linear meter occupation.


Other benefi ts characterising the HT1200I: modern electronics, straight forward process and short fl ow path that minimises the rinse time and analyser consumable consumption. That’s why you cannot give up on HT1200I for your spectroscopy applications.


More information online: ilmt.co/PL/j66O 58838pr@reply-direct.com


Benchtop MALDI-TOF Mass Spectrometer with Dual-polarity Ion Source


Shimadzu has introduced the new MALDI-8030, a compact, high-performance MALDI-TOF Mass Spectrometer with dual- polarity ion source to enable users to analyse molecules in both positive and negative ion mode. The new MALDI-8030 brings the same world-class specifi cations of larger, more expensive MALDI-TOF models into a smaller format, resulting in a versatile, space-spacing, easy-to-use, high-performance alternative, and thus expanding the range of solutions offered by Shimadzu’s industry-standard family of benchtop matrix-assisted laser-desorption/ionisation time-of-fl ight (MALDI-TOF) mass spectrometers.


More information online: ilmt.co/PL/5lA0 58726pr@reply-direct.com


Powerful OEM-IMS Module


The MaSaTECH OEM-IMS Module is a powerful analytical instrument. The module is ideal for users who wish to integrate IMS into their solution. The OEM Advanced Ion mobility spectrometer offers wide range of setups, and is ideal for users who are interested in a powerful analytical instrument with integration requirements. The OEM-IMS Module presents all the advantages of the ion mobility spectrometry technique. All operation parameters are fully adjustable by the user, making this instrument suitable for integration to various analytical applications, as well as for clean room monitoring in the semiconductor industry.


The OEM IMS is able to operate in atmospheric and subatmospheric pressure conditions. All parameters, such as the shutter grid pulse width and period, drift fi eld intensity, aperture grid electric potential, temperature and many others can be controlled. AIMS parameters can be setup by the user. The instrument can be used for industry applications as well as for laboratory research. The IMS is controlled by MaSaTECH software, which allows users to manage all OEM IMS parameters. MaSaTECH’s software source code is open and can be modifi ed by the user.


The instrument is primary dedicated for real time monitoring of Total Acids, Ammonia, Siloxane, volatile organic compounds and interface as a GC detector.


The high sensitivity of the IMS technique in the MaSaTECH instrument is improved by the corona discharge (CD) ionisation source. Among the other advantages, such as, non-radioactivity and higher ion yield generation, it offers CD selective reactant ions generations.


More information online: ilmt.co/PL/Q23R 58196pr@reply-direct.com


New Mass Spec Solution Simplifi es Analysis of Macromolecular Complexes


An innovative mass spectrometry solution from Thermo Fisher Scientifi c Inc provides proteomics and biopharmaceutical laboratories, working in drug discovery and R&D applications, the ability to clearly decipher complex mixtures of large macromolecules.


The Thermo Scientifi c Direct Mass Technology mode augments Thermo Scientifi c Q Exactive UHMR Hybrid Quadrupole-Orbitrap mass spectrometers with charge detection capabilities, allowing direct mass determination of hundreds to thousands of individual ions in a single spectrum. As a result, laboratories can measure mass for complex heterogeneous mixtures of multiple charged components, unlocking new and rich insights into proteoforms, biotherapeutics and next-generation drug modalities.


“Direct Mass Technology mode combines charge detection with our trusted high-resolution accurate mass Orbitrap measurements to achieve results unattainable by current ensemble measurement techniques,” said Iain Mylchreest, Vice President, Research and Development, Analytical Instruments, Thermo Fisher Scientifi c. “By dissolving the complexity barriers inherent to other approaches, we’re enabling a wealth of investigations that were once fi rmly out of reach - from resolving heavily modifi ed proteoforms to revealing small changes in large antibody-drug conjugate complexes, to name but a few.”


Neil Kelleher, Director, Northwestern Proteomics & the Chemistry of Life Processes Institute, Northwestern University, said: “The differences seen when moving from traditional mass spectrometry to this game-changing direct mass technology are profound. We’ve gone from having no data or uninterpretable data to having rich spectra laying bare proteoform complexity. With such solutions, we no longer need to be overwhelmed by the complexity of the human proteome. This technology makes clear that, ultimately, we can build tools that match the complexity and scale of our biology.”


More information online: ilmt.co/PL/x9K1 and ilmt.co/PL/Lyve 58057pr@reply-direct.com


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