Chromatography 13 Software Assists Precise Flow Monitoring
Testa Analytical has introduced version 1.4 of its flowmeter software for continuous monitoring of liquid flow from an analytical or preparative HPLC system, peristaltic pump, flow chemistry system or mass spectrometer.
Operating in conjunction with the Testa Liquid Chromatography flowmeter the easy-to-use PC software app enables fast, simple experimental set-up and provides full control of device settings including integration time and calibration factor.
The software app will also report average and minimum / maximum values of the measured flow. All flow data is automatically stored in files that can be processed later using almost any commercial data analysis package.
Conveniently powered via a USB connection, the compact Testa Liquid Chromatography flowmeter uses a thermal sensor that provides extremely accurate, sensitive, and high-resolution measurement of flow in real time. As the sensor is non-invasive it can operate over a wide dynamic range and has been demonstrated to be the perfect real-time flow monitoring tool for a growing range of liquid applications.
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ilmt.co/PL/j6Zv 58935pr@reply-direct.com New Bioinert (U)HPLC Columns for High Accuracy Analysis
Several substances are able to interact with more common ‘inert’ column hardware materials such as stainless steel or titanium. Critical substances in particular are oligonucleotides or nucleotides. Further sensitive substances are various peptides and proteins as well as coordinating small molecules. The adsorption on metallic surfaces typically leads to peak tailing, loss of recovery and sample carry over. This behaviour can especially be seen when a new column is used without any conditioning before the actual analysis.
For these challenging substances YMC is offering different bioinert hardware options for their YMC-Triart columns. The newly released YMC-Accura Triart (U)HPLC columns are characterised by a bioinert surface coating of the column body and frit. The coating is less hydrophobic compared to the PEEK lining used in the YMC-Triart metal-free (U)HPLC columns. These 2 options allow for the optimum hardware for analyses of any sensitive compound. Further, YMC-Accura columns are ready to use without any preconditioning, which is usually required for analysis of sensitive substances using standard columns.
Due to its organic/inorganic hybrid silica base material, YMC-Triart stationary phases contain no metal impurities. In combination with the bioinert YMC-Accura column hardware, YMC-Triart columns show excellent peak shapes for sensitive compounds, prevent carry over and ensure complete recovery. They are especially ideal for the use in highly sensitive LC/MS analyses.
All 8 YMC-Triart phases are available in inert YMC-Accura columns - with 1.9 µm for UHPLC or 3 or 5 µm for HPLC. The preferred choices for e.g. oligonucleotide or peptide separations are YMC-Triart C18 or YMC-Triart C8 with a pore size of 120 Å. YMC-Triart Bio C18 or Bio C4 with a larger pore of 300 Å are particularly suitable for more hydrophobic oligonucleotides and larger peptides or proteins. Other column options are the polar YMC-Triart Diol-HILIC, the aromatic YMC-Triart Phenyl and PFP and the extremely hydrophobic YMC-Triart C18 ExRS.
More information online:
ilmt.co/PL/2WLP and
ilmt.co/PL/nRML 58354pr@reply-direct.com
Next Generation Scale up Flash Purification CombiFlash Torrent®
reliability of their CombiFlash and RediSep®
systems from Teledyne ISCO provides the ease of use and high product lines in a large, development-scale
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platform. Packed with time-saving features and controlled by our innovative PeakTrak® software, the CombiFlash Torrent accommodates a broad range of injection, detection, and collection requirements. Choose from two models: CombiFlash Torrent for a combination of normal phase and reverse phase purifications, or CombiFlash Torrent AQ optimised for reverse phase.
ed to reach 500,000 readers*
Tailor a system to meet your needs with a variety of sample introduction and fraction handling configurations.
Teledyne ISCO’s powerful yet intuitive PeakTrak software - the industry standard in flash chromatography - lets you quickly access and edit every method parameter from one screen.
Request a quote:
ilmt.co/PL/Y06E Download the Teledyne ISCO Flash Guide:
ilmt.co/PL/oYv5 More information online:
ilmt.co/PL/R2dv
o reach 500,000 readers*
58423pr@reply-direct.com *Average Pass-on rate = 3.2
To find out more visit
https://www.ellutia.com/nitrosamines-in-drugs
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email:
info@ellutia.com tel: +44 (0)1353 669916
Print, Online andDigital Media combined to reach 500,000 readers* *Average Pass-on rate = 3.2
Patented active solvent sensing technology monitors solvent supply and waste levels for true walk-away automation. Pressure and vapour sensors ensure safe operation by stopping the purification when pressure increases or a leak is detected. Fully grounded tubing allows safe operation at high flow rates. Optional air purging of the column after use simplifies disposal.
Available via our app on your smart phone or tablet.
*Average Pass-on rate = 3.2
NDMA in Drugs Test For
Solutions for the analysis and screening of Nitrosamines in Pharmaceutical Drugs
800 Series TEA
The Ellutia 800 Series TEA can be interfaced to a chemical stripping system to quickly monitor ATNC (Apparent Total N-nitroso Content) and interface to a Gas Chromatograph to indentifiy and quantify any volatile nitrosamines present such as NDMA.
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