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New Improved Live Cell Imaging System
Chip-Man Technologies Ltd has announced the launch of the Cell-IQ 2 live cell imaging and analysis system. This innovative platform builds on the success of the original Cell-IQ system, offering fully automated imaging and analysis for the study of live cell behaviour in an optimised and stable environment. The Cell-IQ platform allows accurate and reproducible quantitation of results for live cell imaging, and has already proven highly successful in a range of laboratory settings. The second generation system provides increased usability and precision for users, offering advanced features for cell biology, functional genomics, drug discovery, in vitro fertilisation, in vitro toxicology and regenerative medicine applications. Chip- Man Technologies CEO, Jane Spencer-Fry, explained: “Cell-IQ 2 offers our customers more flexibility, greater ease of use and increased analysis power. The system’s intuitive user interface has also been updated, with the addition of the new Analyser Pro-Write™ software for greater functionality.”
Circle no. 262 Now a Data Logger for Luminance, UV, Temperature & Humidity
TandD Corporation has introduced its new TR-74Ui Four Parameter Data Logger. The TR-74Ui Illuminance UV Recorder can simultaneously measure and record four parameters: Illuminance, Ultraviolet Light (UV), Temperature and Humidity. In addition to these parameters, the TR-74Ui is also capable of displaying Cumulative Illuminance and Cumulative Amount of Ultraviolet Light in the LCD display.
The wide Luminosity range covers 0 to 130k lx and Low Light Resolution to 0.01 lx. The UV Range covers 0 to 30 mw/cm2. Internal Accumulation of Exposure is for both Light and UV. The TR-74Ui has a wide range from 10 to 99% Relative Humidity along with an expanded Temperature range from 0° to +55°C.
This compact, lightweight unit is approximately 2" X 3" and operates on one AA battery. The TR-74Ui has a large data capacity which can store up to 8,000 readings times 4 channels for a total of 32,000 readings in One-Time or Endless recording mode. Simply by connecting to a computer via a USB port, the recorded data can be quickly downloaded with the easy-to-use software.
Circle no. 263
Super Resolution Microscope Systems
The Carl Zeiss ELYRA microscope systems introduce two discrete super resolution techniques to optical microscopy for the first time. Structured Illumination Microscopy (SIM), developed by scientists at the University of San Francisco, and Photoactivated Localization Microscopy (PAL-M) each offer extraordinarily high resolutions that overcome the classical diffraction limit to microscopic resolution. Compared to conventional microscopy, super resolution images have up to double the resolution in all three spatial directions, down to less than 200 nanometers. The ability to resolve to this level within the living cell opens up original experimental possibilities, especially in cell biology and neurological research.
PAL-M technology offers the highest resolution currently available while the outstanding feature of SR-SIM technology is its high level of flexibility in the choice of dye. This means that both super resolution methods minimise previous limitations in dye selection or user-friendliness and that users no longer need to invest in single extremely specialised and expensive systems.
Three microscope systems are being offered. ELYRA S.1 is the first microscope system to offer SR-SIM technology on a standard microscope stand while ELYRA P.1 offers PAL-M technology commercially for the first time. The ELYRA PS.1 offers both technologies in one system and in combination with a laser scanning microscope, meaning that that an object can be successively imaged with LSM, SR-SIM and PAL-M. The optimal combination for high-end research is offered by ELYRA in conjunction with the LSDM 780 laser scanning microscope. However, PAL-M and SR- SIM may also be combined with the LSM 710 system.
Circle no. 264
Pushing the Boundaries of Fluorescence Imaging
Olympus has introduced a new, highly versatile, range of cutting-edge research microscope systems. The Olympus xcellence live cell imaging system range is designed to bring the most advanced fluorescent imaging techniques within easier reach, whilst pushing the very boundaries of optical imaging. The Unix-based controller provides the high-speed parallel component management required to ensure that each procedure can capture the most advanced data. The xcellence software includes the Experiment Manager, a universal planning and execution tool with logic and simple drag-and-drop experiment construction. Olympus xcellence provides the ultimate system for imaging live cells over prolonged periods of time with the Olympus MT20 fluorescence lightsource providing highly stabilised mercury or mercury-xenon burner control with very fast filter, attenuator and shutter changes. The new total internal reflection fluorescence microscopy module, cell^TIRF, features 4 laser lines with separate motorised angle control enabling synchronised acquisition with identical penetration depth. The xcellence software enables the user to set incident angles or penetration depths with ease, as well as running experiments with varying penetration depths. This, combined with the broadest selection of TIRFM objectives, provides a new level of precision in multi-colour TIRFM.
The cell^FRAP system offers the state-of-the-art in photo control technology, enabling advanced FRAP, iFRAP, FLIP, FLAP, photoactivation and photoconversion. Optically, the FRAP module can incorporate two separate laser lines or a laser combiner and is introduced into the microscope via a separate light-path to the camera and fluorescence illumination. This ensures full integration of FRAP with epi-fluorescence, TIRFM and laser spinning disk techniques, and enables simultaneous imaging and photo-manipulation as well as µsec switching. The Olympus cell^SPIN has been developed as a bright laser spinning disk confocal system with the highest emission efficiency on the market. What is more, as well as using optimised disks for perfect confocality with different objectives, the system has full control over the disk speed and offers a maximum speed of 5600rpm. As a result the Olympus cell^SPIN can provide up to 367 confocal images per second.
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Spotlight
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