54 New Japanese Basket Sinkers
SMI-LabHut are pleased to announce the introduction of two new capsule sinkers to complement their existing extensive range of dissolution weights and sinkers. The CERTBSK-JP Japanese Pharmacopoeia basket sinker and the CUSBSK-JPMAG magnetic basket sinker have been manufactured in strict compliance with both the USP Pharmacopoeia, General Chapter (711) Dissolution and the Japanese Pharmacopoeia, General Chapter (15) Dissolution.
All sinkers are supplied with a certificate of compliance, and are manufactured using a proprietary technique that not only ensures exact specification, but also extends the usable life of the baskets.
The CUSBSK-JPMAG is the only magnetic Japanese sinker available and has been innovatively designed to be used with robotic removal equipment to automatically retrieve the magnetic sinker.
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LABORATORY PRODUCTS
Real Time Airflow Control in Biosafety Cabinets
LabGard™ ES and CellGard™ ES Class II Biological Safety Cabinets utilise IntelliFlow™ airflow sensor technology through the use of the TouchLink™ Electronic Control System. The IntelliFlow™ airflow sensor incorporates the same thermal anemometer technology used by service technicians (certifiers) to annually verify the biological safety cabinet’s airflow performance. The system works by being calibrated by the certifier, then the TouchLink™ Electronic Control System will maintain and control the cabinet’s airflow through the use of thermal anemometer airflow sensors manufactured by measurement solution company TSI, Inc™.
NuAire’s®
The IntelliFlow™ airflow sensors are strategically placed under the supply filter and over the exhaust filter to measure airflow real time. Airflow data is digitally communicated to the TouchLink™ Electronic Control System where fan/motor speed is adjusted to provide you with true constant laminar airflow. Measured and controlled airflow provides peace of mind that your Biological Safety Cabinet is operating at optimal safety containment performance levels.
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Unique Oxygen Sensor for IVF and Cell Culture Incubators
DNA Sequencing Finds Mutations in Small Cell Lung Cancer Line
Applied Biosystems has announced the publication of a paper in the journal Nature that demonstrates the power of next-generation DNA sequencing used to identify DNA mutations in a small cell lung cancer (SCLC) line and identify the mutational burden associated with tobacco smoking.
The paper, authored by researchers from the Wellcome Trust Cancer Institute and co-authored by Applied Biosystems, demonstrates the potential for next-generation sequencing to provide unprecedented insights into mutational processes, cellular repair pathways and gene networks associated with cancer development.
laboratory monitoring system from IKS can accurately monitor the oxygen levels in up to 16 incubators.
Based on the proven and also unique XiltriX CO2 monitor, a single high performance oxygen sensor is combined with
programmable sample switching so that the oxygen level in each of up to 16 incubators can be measured every 20 minutes. Automatic calibration can be programmed at selected intervals
for long term accuracy and stability, and if a XiltriX CO2 sensor system is also in use there is no need for additional calibration gases as ambient air can be used as the oxygen standard and the CO2 calibration mixture as the zero standard!
XiltriX Product Manager Han Weerdesteyn, said: “Long term oxygen stability monitoring is vital for growing embryos under lowered oxygen conditions.
For multiple-incubator installations, this new oxygen sensor substation combines with XiltriX to give the easiest, cheapest and most accurate solution for monitoring up to 16 incubators, and will help to further improve IVF success rates.”
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Many IVF and cell culture laboratories are using incubators with reduced oxygen levels in order to more closely reflect in vivo conditions and so improve embryo or cell viability. A unique new multi-channel oxygen sensor substation for the XiltriX®
“The publication of this paper emphasises the power that next-generation sequencing, such as Applied Biosystems’ SOLiD™ System, has to improve science’s understanding of disease and it’s potential to develop better diagnostics and therapeutic treatment,” said Kip Miller, President, Genetic Systems for Life Technologies. “Today’s SOLiD 3 Plus System offers even more capability and is faster, more robust and more economical than the SOLiD 2.0 System that generated the data in the paper.”
These impactful results were generated at the Sanger Institute using an early version of the SOLiD System. Massively parallel sequencing on Applied Biosystems’ SOLiD 2.0 System enabled the researchers to identify all of the mutations in the SCLC line NCI-H209 and compare them to a matched normal cell line.
Data identified several mutation signatures that reflect the wide range of carcinogens in tobacco smoke, which is notable because 90 percent of patients with SCLC smoked during their lives.
Today’s SOLiD 3 Plus System is capable of generating over 60Gb of mappable sequence at an accuracy greater than 99.95%.
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RIA Workflows get a Boost
Shin Jin Medics, Inc in Koyang-Si, South Korea, a manufacturer of in vitro immunodiagnostic products, has chosen Tecan’s Freedom EVO®
platform as a critical component in its automated radioimmunoassay (RIA) workflow solution, the RIA Automated Laboratory System (RALSystem).
Mr Seung-Jae Lee, Manager of Diagnostic Instrument Engineering at Shin Jin Medics, explained: “We developed the RALSystem, consisting of Tecan’s Freedom EVO 150 liquid handling workstation integrated with our gamma counter, washer and shaker, to perform automated RIAs. We chose the Freedom EVO for the sample handling of the workflow because of its flexibility and compatibility with our own systems; our proprietary tube rack carries the total workflow through all four devices, minimising human error and saving labor and time. The Freedom EVO takes 10 minutes to distribute 100 samples into 500 reaction tubes, and the whole process from sample distribution to results takes about one or two hours, compared to several more hours it would take to do these assays manually.”
“We received comprehensive training from Tecan for running and maintaining the instruments, as well as application and software support. We have been using the Freedom EVO routinely in the RALSystem since the beginning of 2008, and everything has worked smoothly, without a problem,” concluded Mr Lee.
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INTERNATIONAL LABMATE - FEBRUARY/MARCH 2010 - LABORATORY PRODUCTS
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