COVER STORY: LIPOID KOSMETIK ADVERTISEMENT FEATURE
MorinGuard: skin protection with purpose PERSONAL CARE
Moringa oleifera, commonly known as the ‘Miracle Tree’, is known for its anti-inflammatory action and celebrated for the cosmetic benefits of its seed oil. The oil production supports thousands of Rwandan farming families, creating vital economic opportunities. A by-product of oil extraction, Moringa seed cake, is ingeniously upcycled by Lipoid Kosmetik to create MorinGuard®, a revolutionary cosmetic active ingredient. MorinGuard® contains moringin, a powerful
bioactive compound that delivers exceptional skin care benefits. It combats inflammation by inhibiting the NF-κB pathway while activating the antioxidative Nrf2 pathway to reduce oxidative stress. This dual-action mechanism minimizes skin damage, fortifies the skin’s defense system, and promotes barrier repair, offering a comprehensive solution for inflammation, and skin barrier regeneration. MorinGuard® represents a new era in cosmetic active ingredients going beyond beauty benefits. It’s more than am ingredient – it’s a statement of care for the skin, the community and the environment.
From upcycled moringa seed cake to cosmetic actives While moringa oil is the primary commercial product derived from the moringa tree, the seed cake left behind after oil extraction—comprising around 85 % of the biomass—is largely underutilized. Despite being rich in proteins and valuable phytochemicals such as moringin, its potential remains untapped. To address this, Lipoid Kosmetik has
developed a cosmetic active from moringa seed cake, preserving and enhancing the value of its bioactive compounds. Moringin, one of the key components, is known for its strong anti-inflammatory and antioxidant properties. It works by inhibiting the pro-inflammatory
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Microcirculation *
September 2025 GLOBAL INGREDIENTS ● FORMULATION ● MANUFACTURE
Interview: Ashland personal care general manager Jim Minicucci
In focus: Skin care Hair care Upcycled ingredients
Plus: California SCC Suppliers’ Day preview
NF-κB pathway and activating the protective, antioxidative Nrf2 pathway. Lipoid Kosmetik sources moringa seed cake
from a supplier with a sustainable and socially responsible supply chain, linking over 1’500 smallholder farmers in Rwanda to the global cosmetic market. This partnership supports their livelihoods through economic growth, sustainable development, and creates a positive social impact.
MorinGuard® reduces inflammation and accelerates skin recovery from irritation MorinGuard® demonstrates significant anti- inflammatory and skin recovery benefits both
14.7 11.6 7.7 7.2 -47% -51%
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Skin Barrier (TEWL) *
* -30% 15.2 13.9 10.7 6.8 Figure 1: MorinGuard® accelerates skin recovery after irritation.
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Lipoid Kosmetik AG Sennweidstrasse 44/46, CH-6312 Steinhausen, Switzerland Tel: +41 (0) 41 748 33 33 E-Mail:
info@lipoid-kosmetik.com Website:
www.lipoid-kosmetik.com
September 2025 PERSONAL CARE -55%
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in vitro and in vivo. Inflammation in skin is characterized by elevated inflammatory markers, matrix-metalloproteinases (MMPs), and nitric oxide (NO). In human dermal fibroblasts stimulated with IL-1β, MorinGuard® significantly reduced levels of key inflammatory markers such as IL-6, IL-8, PGE2, and 8-isoprostane, indicating its ability to soothe inflammation and support skin health. In human keratinocytes (HaCaT) treated with Poly I:C, the compound reduced the synthesis of MMP-1 and MMP-9—enzymes responsible for collagen breakdown and immune cell migration, thus, helping preserve skin structure. Additionally, in LPS-stimulated immune cells, MorinGuard® dose-dependently lowered NO production, reducing oxidative stress and redness (data not shown). An in vivo study further confirmed the protective role of MorinGuard® role in skin recovery. Following skin irritation via dermaroller needling, MorinGuard®—alone and in combination with Lipoid Kosmetik’s SLM Skin Lipid Matrix®, a biomimetic lipid complex—significantly accelerated skin recovery. Microcirculation normalized 47 % faster with MorinGuard® alone and 51 % faster with MorinGuard® + SLM. Similarly, skin barrier function (measured via TEWL) recovered 30 % faster with MorinGuard® and 55% faster when combined with SLM (Figure 1).
Conclusion MorinGuard® is a COSMOS- and NATRUE- approved, effective and eco-friendly active ingredient based on the upcycled and traceable moringa seed cake. It significantly accelerates the recovery of irritated skin, especially in combination with SLM Skin Lipid Matrix® making it a great choice for skin recovery and protection. MorinGuard® represents a new era in cosmetic active ingredients going beyond beauty benefits. It’s more than a product – it’s a statement of care for the skin, the community, and the environment.
PC
Recovery time (h)
Recovery time (h)
Untreated Placebo 2% MorinGuard®
2% MorinGuard® +20% SLM Eco®
Untreated Placebo 2% MorinGuard®
2% MorinGuard® +20% SLM Eco®
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