Virtual Early Career European Microscopy Congress 2020


To be held on 24th – 26th November 9am – 5pm UK Time, 10am – 6pm CET Time


Scientifi c Organisers: Klaus Qvortrup (Conference Chair), Marco Beleggia, Jakob Birkedal Wagner, Eija Jokitalo and Julia Fernandez- Rodriguez.


Following the cancellation of emc2020, this virtual meeting will provide an opportunity for Early Career Scientists who would have attended and presented at the congress, to still present their work at an International Meeting this year.


Symposia/Sessions taking place:


Physical Sciences Applications Physical Sciences Tools & Techniques Life Sciences – Ultrastructural imaging in life sciences Life Sciences – from molecules to complex systems


Each symposia will have a morning and afternoon session with oral presentations, as well as poster sessions.


To register to attend the Virtual Early Career European Microscopy Congress - 2020, you must have an account on the emc2020 website.


If you attended mmc2019 you will already have an account, otherwise you should follow the registration process on the website.


Ticket Categories:


Students and early career researchers free. EMS members €60. Non-members €75. Sponsorship is also available for the meeting.


For all registration, sponsorship details and other enquiries visit www.emc2020.eu


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RMS Meeting: Frontiers in


BioImaging 2020


To be held on 17th – 18th November 2020 this virtual meeting will bring applications of optical, electron and correlative microscopy, as well as biocomputation. Invited speakers (from across the globe) will be presenting in sessions their recent technical developments and applications of these microscopy-based approaches to address key cell and molecular biology questions.


Submitted abstracts will have the chance to present their data and partner companies will showcase their recent products in Techno Bite sessions. Join us (virtually) to learn and discuss the latest progress and application of microscopy and image analysis.


Scientifi c Organisers:


Professor Mark Leake University of York. Chair of Biological Physics, Head of Biological Physics Group


Dr Leandro Lemgruber, infocus Deputy Scientifi c Editor. Wellcome Centre for Molecular Parasitology, University of Glasgow


Dr Theresa Ward, Life Sciences Section Chair London, School of Hygeine & Tropical Medicine


Event contac: Kat Driscoll.


Further information: katdriscoll@rms.org.uk Visit www.rms.org.uk


53465pr@reply-direct.com Flow Cytometry Facilities Meeting 2021


This Flow Cytometry Facilities meeting on 5-6 Jan 2021 is aimed at those managing or working in fl ow cytometry facilities and will be going virtual.


To be included in our next issue, send all your News stories to:


heather@intlabmate.com


As in previous years, the meeting is aimed at all those that run or work in a Flow Facility and seeks to address common subject matters, themes, and circumstances within the community. We will also focus on new and emerging technologies as well as operational aspects of running, and working in, a core. We will include presentations from current core facilities (Crib talks) and also from our industry colleagues (Technobites). The meeting will be run over two afternoon sessions (14:00-18:00 GMT) to allow our American colleagues to join us. Although in a virtual format, there will be ample time in the programme for discussion and questions from the community.


The virtual meeting will take place at 14:00-18:00 GMT, 09:00-13:00 ET; 15:00-19:00 CET.


Scientifi c Organisers: Dr Alexis Conway Roswell Park Comprehensive Cancer Center


Mr Derek Davies Flow Cytometry Section Chair, The Francis Crick Institute


Dr Karen Hogg University of York Dr Rachael Sheridan Van Andel Institute


Dr Peter O’Toole, RMS Vice President . Head of Imaging and Cytology Labs, University of York


Event Contact: Kate Wooding. Further information kate@rms.org.uk Visit www.rms.org.uk


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Properties of Superbug Killer Revealed by STFC Imaging Cluster


A research team led by the University of Sheffi eld has used high resolution microscopy techniques at STFC’s Octopus imaging cluster to investigate the properties of a compound which kills antibiotic-resistant superbugs. The fi ndings have led to the development of a new compound that has killed antibiotic-resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and E.Coli, during tests.


Despite having different cell wall structures, the new compound was found to be able to kill both gram-negative and gram-positive bacteria by passing through the cell wall of both forms and then binding to the DNA. Doctors have not had a new treatment for gram-negative bacteria in the last 50 years and no potential drugs have entered clinical trials since 2010, so this research could lead to new treatments for these antibiotic-resistant superbugs.


The Octopus imaging cluster, part of the UK’s Central Laser Facility located in Harwell, Oxfordshire, allowed the researchers to look at how the new compound moves and act using a super resolution microscopy technique, Stimulated Emission Depletion (STED), using a specially developed dye to show fl uorescence in the compound.


Dr Jorge Bernardino de la Serna from Imperial College London was part of the research team, bringing expertise from his former role as a spectroscopist at CLF and continuing visiting scientist at the facility. He said: “The cellular laboratories at CLF, equipment capabilities and know- how of the experienced staff within Octopus has been instrumental to be able to resolve the mechanism of action of this antimicrobial at the nanoscale. The ruthenium-based dyes uniquely display fl uorescence properties which can nicely resolved employing a type of super resolution microscopy, STED (Stimulation Emission Depletion).”


The University of Sheffi eld’s Professor of Bio-inorganic Chemistry Jim Thomas led the research team. He said: “The identifi cation of these novel antimicrobials and their mode of action has been


Antibiotic-resistant superbugs like MRSA and e.Coli could be targeted by the compound. Credit: Gerd Altman/Pixabay.


greatly accelerated by the intrinsic luminescent properties. To be able to probe their uptake, intracellular localization and directly see how they kill bacteria at the amazing resolutions supplied by STED has been a huge catalyst in their development.”


The research was published in Chemical Science. 53466pr@reply-direct.com


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