41 Clinical, Medical & Diagnostic Products Testing Multiple Faecal Markers from One Stool Sample Extract
Determination of several stool parameters from a single stool sample is often difficult because the sample material may be not enough, the analytes may not be stable in the sample, and it means considerable additional workload.
To this purpose Immundiagnostik AG offers a stool sample preparation device pre-filled with IDK Extract®, a universal stool extraction buffer. This combination makes stool diagnostics easy, fast and hygienic.
The stool sample preparation device is dipped into 3 separate spots of the stool sample thereby collecting a defined amount of stool (15 mg) with minimal handling of the sample. Afterwards the sample is simultaneously extracted and pre-diluted with IDK Extract® in a single step. The stool extract can then be used for the analysis of up to 14 stool parameters.
As an additional benefit, IDK Extract® stabilises the different analytes in the stool sample extract. Thus, sample extraction and analyte testing can be performed on separate days, and the testing can even be spread over several days.
IDK Extract® - one buffer and one sample extraction step for complete stool analytics with up to 14 parameters - saves time and money. Especially developed for Immundiagnostik AG - your competent partner for stool diagnostics.
More information online:
ilmt.co/PL/XaAZ 53345pr@reply-direct.com
Fully Scalable Solution for Clinical Laboratory Reagent Water Announced
The Avidity Science GENO™ CL is a fully scalable one-box solution providing consistent and compliant supply of CLRW up to 200 L/hr (0.88 GPM) flowrate. The system’s twin stream cassette technology provides the contingency required in the modern laboratory within a single platform ensuring continued assurance of supply of pure water at all times.
Designed to accommodate the changing needs of clinical laboratories, the GENO™ CL is versatile, flexible and easy to operate with a 10-inch intuitive, icon based, touch screen. The system minimises spatial requirements, whilst reducing the risk of water outage; all in a single cabinet.
More information online:
ilmt.co/PL/rZDp 53345pr@reply-direct.com
New Positive Validation Data for DNA Extraction Kit Announced The UK genomic tools developer,
RevoluGen Ltd, has announced new data validating the performance of its high-molecular weight (HMW) DNA extraction kit, Fire Monkey. Scientists at the UK’s Quadram Institute together with collaborators in Pakistan have published positive results from Illumina whole genome sequencing (WGS) for extensively drug-resistant (XDR) Salmonella Typhi characterisation in Pakistan, using Fire Monkey.
Salmonella Typhi are bacteria which infect the intestinal tract and the blood, causing typhoid fever. In 2016, an outbreak of a strain of the bacteria resistant to many of the usual antibiotics used to treat the disease (XDR S. Typhi) was reported in the Sindh province of Pakistan. Further spread of the outbreak is of serious concern due to the limited options for treatment. The research involving scientists at the Quadram Institute identified 27 XDR S. Typhi isolates from patients at Jinnah Hospital in Lahore, the capital of the Pakistani province of Punjab, between January and April 2019. All isolates were of the same genotypic background as the outbreak strain from Sindh province, as confirmed by Illumina whole genome sequencing. Importantly the first emergence of XDR S. Typhi in Punjab province was confirmed by this whole genome sequencing and analysis.
“We have found Fire Monkey to be very quick and easy to work with. We are now keen to take advantage of its step-change in length of DNA fragments, thus enabling multiplexed long-read sequencing. We look forward to continuing our relationship with RevoluGen to explore the role of its technology in metagenomic analysis and to explore automation” commented Dr Gemma Langridge, Group Leader, Quadram Institute.
Pieter Haitsma Mulier, CEO of RevoluGen commented: “Microbial sequencing is now becoming routine and provides an important tool for disease surveillance, accurate and rapid diagnosis, as well as for monitoring and profiling antibiotic resistance. This publication from the Quadram Institute provides key validation of Fire Monkey/ Fire Flower for use in this field.”
The paper ‘Emergence of Resistance to Fluoroquinolones and Third-Generation Cephalosporins in Salmonella Typhi in Lahore, Pakistan’ by Rasheed et al (2020) is available online from the journal Microorganisms at
ilmt.co/PL/5gR6
More information online:
ilmt.co/PL/JKne 53221pr@reply-direct.com
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