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Test Kit Identifies Genetic Risk of Thrombosis
Compact Balances
Adam Equipment, a worldwide manufacturer of high-quality and affordable electronic scales and balances, offers its Core™ Compact Balances for the classroom and general laboratory use.
The durable and compact Core balances come in seven models and are designed for easy storage, making them perfect for the classroom setting. The battery and AC power supply also make them portable and useful for fieldwork. The Core is extremely affordable and comes with a large backlit digital display, colour-coded keypad and a removable stainless steel pan. Other useful features include full-range tare and dual tare keys, zero tracking, simple four-button operation and external calibration.
The Core offers overload protection in case of accidental overloading. The removable draft shield, available on most units, provides added stability and improves accuracy. The Core also has a security feature — a slot that allows the use of a standard Kensington™-type lock and cable to prevent theft.
Circle no. 181
Astra Biotech GmbH announces a new genetic test kit which identifies hereditary thrombophilia – a significant risk factor in the development of potentially life- threatening deep vein thrombosis and pulmonary embolism. In line with the company’s aim of facilitating disease prevention and improving quality of life, the Astra Thrombosis kit detects three common mutations which disrupt the blood coagulation mechanism. The consequences of thrombosis can be severe – pulmonary embolism (PE), myocardial infarction, stroke and infertility – and thrombosis is one of the most widespread causes of morbidity and mortality in developed countries. Hereditary thrombophilia, the propensity to develop thrombosis, is an important factor influencing development of deep vein thrombosis (DVT) and PE. Additional risk factors include pregnancy, prolonged immobilization, surgical intervention, injury and smoking.
The Astra Thrombosis kit enables identification of hereditary thrombophilia and estimation of a patient’s risk of developing DVT and PE. Following extraction of the patient’s total DNA sample from blood tissue or epithelium, three single nucleotide polymorphisms in the F5, F2 and MTHFR genes can be simultaneously detected using the kit. The method is multiplex PCR with subsequent restriction and polyacrylamide or agarose gel electrophoresis. The diagnostic kit includes two PCR mixes, positive controls, DNA- polymerase, restriction enzyme and buffer. Testing for hereditary thrombophilia is recommended in various circumstances, such as venous embolism occurring before the age of 50, repeatedly, or during pregnancy or the postnatal period, and for members of families with expressed hereditary thrombophilia.
Circle no. 182
Excitation Wavelength Selection with a Flick of the Thumb
With the most recent introduction of a new multi- wavelength excitation-laser coupling unit WITec has further advanced the ease-of-use of its microscope series. It is now possible to switch between up to three laser sources by the simple rotation of a filter wheel. Calibration and alignment of the laser beam path is guaranteed at all positions assuring accurate and variable Raman Imaging. Each excitation wavelength features a high quality and wavelength optimised filter set, enabling the highest throughput and greatly contributes to the exceptional speed and sensitivity of WITec’s systems. Experiments specifically requiring a variety of lasers, for example, to eliminate fluorescence can benefit from such a multi-laser setup, making the alpha300 and alpha500 series even more versatile and applicable to a wide range of applications.
Circle no. 183 ADVERTORIAL
Automated Production of High Quality Blood Agar
Integra has released a new application note that demonstrates how combining its MEDIAJET Petri dish filler with the DOSE IT peristaltic pump provides an optimised automated solution for the production of high quality blood agar.
The new application note describes an automated protocol that minimises the time that the blood is exposed to hot agar medium and thus efficiently reduces thermally induced lysis of erythrocytes. By preparing the blood agar using an INTEGRA MEDIACLAVE media preparator, the dispensing temperature can be set and maintained at low temperature. Furthermore by combining the MEDIAJET Petri Dish filler together with a DOSE-IT peristaltic pump and a special tubing set for blood agar the experimenters were able to add blood to the agar immediately before pouring the plate thereby reducing blood cell lysis significantly.
www.integra-biosciences.com/pdf/liquid_handling/ Blood_agar_preparation_V00.pdf
Circle no. 184
New 96-Channel Handheld Electronic Pipette
The Integra VIAFLO 96 is a new 96-channel electronic pipette that enables fast, precise and easy simultaneous transfer of 96 samples.
The VIAFLO 96 has been designed to be used just like a standard handheld pipette. Therefore, no special skills or training are required to operate it. The VIAFLO 96 features the company’s popular Touch Wheel™ pipette user interface enabling simple and fast programming of a wide range of pipetting modes including repeat dispense, serial dilute and sample dilute.
Customers will immediately benefit from the increased productivity delivered by their VIAFLO 96. Fast replication or reformatting of 96 and 384 well plates and high precision transferring of reagents, compounds and solutions to or from microplates is now as easy as pipetting with a standard electronic pipette into a single tube.
Four pipetting heads with pipetting volumes up to 12.5 µl, 125 µl, 300 µl or 1250 µl are available for the VIAFLO 96. These pipetting heads are interchangeable within seconds enabling optimal matching of the available volume range to the application performed.
Circle no. 185
Circle no. 186
INTERNATIONAL LABMATE - AUGUST/SEPTEMBER 2011 - LABORATORY PRODUCTS
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