29 Stability Tests in the Climate Chamber ICH
The new Memmert climate chamber ICH has been specifically designed for stability tests in accordance with GMP and ICH guidelines.
In order to uniformly heat or cool the chamber, Memmert deploys an air jacket temperature control system in its new climate chamber ICH 256. Thanks to the excellent temperature and humidity homogeneity resulting from this, the new Memmert appliance meets the most important requirement demanded of stability test chambers in the pharmaceuticals, food and cosmetics industries. For stability tests in accordance with ICH Q1A, it covers a temperature range from -10°C to +60°C and a relative humidity range from 10 to 80%.
In addition, the new ICH 256L model, equipped with an illumination unit, can be used to perform photostability tests in compliance with standard ICH Q1B, option 2.
Circle no. 93 New Heated Circulation Bath
Hoefer, Inc has introduced its new RCB20-PLUS Refrigerated/Heated Circulation Bath, which provides efficient temperature control for all types of electrophoresis, transfer techniques and general laboratory applications.
The unit provides temperature control in the -10°C to +100°C range, regulated to ±0.03°C.
With a compact footprint, the RCB20-PLUS is just 23cm wide x 40cm deep and is designed for continuous use. The heater wattage is 1000 W and the circulation pump rate is 12L per minute.
The RCB20-PLUS is outfitted with a low liquid volume sensor to prevent damage to the unit. The compressor uses R134A refrigerant and includes a sensor that identifies irregular temperatures and prevents overheating.
Circle no. 94
No. 836 is a 750OF electrically-heated Class 100 cleanroom oven from Grieve, currently used to bake various coatings onto products at a customer’s facility. Workspace dimensions of this oven measure 36” wide x 36” deep x 39” high. 30 KW installed in Incoloy sheathed tubular heating elements provide the maximum temperature of 750OF, while a 1000 CFM, 1 ½-HP recirculating blower maintains horizontal airflow across the load.
No. 836 features a Type 304, 2B finish stainless steel interior with continuously backwelded seams, an exterior finished with white epoxy paint #4, brushed finish stainless steel door face and control panel face. The oven has 6” insulated walls and an aluminised exterior.
Additional equipment on this Grieve oven include a 30” x 24” x 6” thick stainless steel high temperature HEPA recirculating air filter, digital programming temperature controller, manual reset excess temperature controller with separate contactors, recirculating blower airflow safety switch and a 10” diameter circular chart recorder.
Circle no. 95 ADVERTORIAL
The G185 Incubator – A Japanese Case story
Portable Incubator for Safe Transport of Living Cells
K-SYSTEMS G95 portable incubator protects gametes and other living cells from temperature, gas fluctuations, and harsh light conditions during transport.
The well-designed unit has a built-in battery, which enables the G95 to maintain a correct and stable temperature level up to 4 hours. The incubator can be connected to a cigarette lighter socket in a vehicle for longer transport. The temperature range can be set from ambient to 49.9°C.
The chamber of the portable incubator can be purged with the desired gas mixture and is easily disconnected from the quick-snap valve located at the back of the G95.
The G95 portable incubator is ideal for field work or for transporting living cells between satellite labs. Culture dishes and/or test tubes are placed and tighten into interchangeable warming blocks for safe transport.
Circle no. 96 Picture: Courtesy of Asada Ladies Clinic & Naka Medical
With several hundreds installations into IVF Laboratories worldwide, K-SYSTEMS G185 Bench top incubator is an ideal device for your laboratory. Sixteen units have been supplied for the Asada Ladies Clinic, Nagoya Aichi in Japan. The clinic initially started with four units and used them for almost a year. After a conclusive published comparison between the G185 and conventional incubators, they opted to equip their new modern facility with twelve more units. “The K-SYSTEMS G185’s advantages are that in culture rooms with limited space, it is smaller than existing models, and cleaning and management are much simpler as it operates without humidification. We also think that it could possibly lead to complete individualisation of embryo culture. In frozen-thawed transfer cycles the Day 3 good embryo rate was significantly higher with the G185”. (Abstract of a published paper in 2010 by Noritaka Fukanaga – Comparison of Embryo Development between a New Concept Incubator and the Current Model.)
The G185 Incubator is composed of 10 individual culture chambers each can accommodate up to 4 dishes. When placing cells in an individual chamber, the G185 has a fast recovery to homeostatic conditions due to fast returns of
temperature, CO2 and O2 levels. Furthermore, the unit is equipped with an integrated VOC and HEPA filter, ensuring a grade A air quality. The G185 is cost effective in daily use due
to a very low gas consumption using 1 l/h of CO2 and 12 l/h of N2. The unit accepts 100% CO2 and 100% N2. Its built-in gas mixer allows a working range of 2-10% of CO2 and 2-20% of O2. The G185 has as a standard Windows®
based data logging system with internal and external alarms. Circle no. 97 Circle no. 98 ELEGANT SPACE SAVING DESIGN K-SYSTEMS® - Kivex Biotec Ltd I Tel.: +45 4599 5600 I
info@K-SYSTEMS.dk I
www.K-SYSTEMS.dk INCUBATOR TECHNOLOGY? READY FOR ADVANCED
THE UNIQUE TRI-GAS BENCHTOP INCUBATOR G185 GIVES YOU THE OPPORTUNITY TO MAINTAIN AN OPTIMAL ENVIRONMENT FOR CULTURING CELLS
- Superior temperature conditions - Recovery time in < 3 min.
- Internal air quality – Grade A - Low gas consumption - Optimal space utilization and
- Connect to 100% CO2
100% N2 for low oxygen - Option for pH monitoring
10 separate culture chambers each accommodates up to 4 dishes. Large warmed compartment for media or tubes.
Class 100 Cleanroom Oven
Spotlight
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