Spotlight Biotechnology & Immunology


Genuine 3D Cell Culture Technology Amsbio has announced the launch of alvetex®


- a unique cell culture scaffold that, for the first time, enables genuine 3D cell culture to be grown routinely and cost-


effectively. Already successfully applied to numerous applications including drug toxicity models with liver cells, skin raft assays and bone remodelling studies - alvetex® provides a stable and inert scaffold for cells to grow, mimicking in vivo growth and formation of tissues in the body. alvetex®


has a highly porous architecture that is


specifically tailored for 3D cell culture and designed to be compatible with existing cell culture techniques and post cell culture analysis. Extensively tested and validated with a large number of cell types, alvetex®


from Amsbio enables the formation of complex 3D cellular structures, increases viability, decreases cell death and enhances


cell function. Available in different formats for short and long term cell culturing, alvetex®


for passaging or flow cytometry. With data on alvetex® offers exceptional flexibility. Using this unique material - cells can be visualised by confocal


or live cell imaging or treated like tissue, it's easy to process for histological staining, immunocytochemistry and electron microscopy. Viable cells can also be isolated by alvetex®


already published extensively in peer-reviewed journals, this unique 3D scaffold offers the potential to revolutionise basic cellular research, disease modeling, drug toxicity screening and cosmetic safety testing. Circle no. 154 Top Quality C. Difficile GDH Immunoassay


Pro-Lab Diagnostics has launched a high quality immunoassay for rapid and accurate screening of patients with suspected Clostridium difficile infection. The Prolisa™ C. difficile GDH (glutamate dehydrogenase) EIA achieves excellent sensitivity and specificity thanks to a mouse monoclonal GDH antibody, and offers a high negative predictive value to quickly and easily rule out C. difficile infection. Many recent studies have demonstrated that C. difficile infection can be identified more efficiently and economically by initially screening for GDH, rather than by testing for toxins alone. Mark Reed, General Manager of Pro-Lab Diagnostics, explained: “Screening for GDH as a marker present in toxigenic and non-toxigenic strains of C. difficile, followed by tests for toxin A or toxin B on GDH-positive samples, is an easy, quick and cost-effective way to test for C. difficile infection, as several UK customers are already finding.” Supported by Pro-Lab Diagnostics’ knowledgeable and friendly team of experts, the Prolisa C. difficile GDH EIA is a manual immunoassay, available in a 96-well test size that has also been optimised and validated for the most widely used automated platforms. Reagents are supplied in larger volumes as standard, to accommodate automated systems and provide more flexibility, and are also available separately, with comprehensive lot-to-lot compatibility


Circle no. 155 ADVERTORIAL Vakuum Filtration ‘rapid’- Filtermax home of tissue culture


Tissue Culture and Laboratory Technology


®


Square form and excellent filter features turn the vacuum filter ‘rapid’ - Filtermax into the choice of your vacuum filtration.


What is the most important thing when filtering media for cell culture? Simply to state: Sterilising media into the reservoir and maximising the amount of protein filtered through. The ‘rapid’ - Filtermax units from TPP Techno Plastic Products AG offer an efficient and effective way of filtration precisely for this purpose.


Vacuum Filtration “rapid” Filtermax 1000 • Buyer flexibility: NEW: flask only, filter set, top only • Secure square footprint eliminates risk of tipping over • Ideal storage flask • Large quadratic filter surface, 20% larger than comparable round forms • Premium PES filter membrane • Low protein binding capacity, high flow rate


The TPP vacuum filtration ‘rapid’ - Filtermax filtration units feature a 0.22 µm PES membrane with the smallest pore size available on the market. By this the filter paper cleans out efficiently even smallest impurities. The high quality PES membrane possesses also an extremely low protein binding capacity. These two advantages are combined with the valuable feature of the large filter surface given by its quadratic form. By this it is 20% larger than comparable round forms.


Thus the ‘rapid’ - Filtermax units provide for a high flow rate, less clogging and impurities and proteins filtered out highly efficient.


However, the square design offers other benefits too. Whether on the shelf or in cold storage the square form of the flask saves valuable storage space. Many content users state that the square design is less likely to tip over during filtration or while working in a hood. Also, the tapered form is easy and secure to hold and less likely to slip out of the researcher’s hand.


Rack for TubeSpin® Bioreactor 600 • New rack to complete Bioreactor family • Optimal fit for 3x TubeSpin® Bioreactor 600 • Ideal footprint to securely store large filled tubes • Convenient, reusable and stackable


Ask us for a free yellow sample case


TPP Techno Plastic Products AG Zollstrasse 155, CH-8219 Trasadingen, Switzerland Telephone +41 (0)52 687 01 87, Fax +41 (0)52 687 01 77 info@tpp.ch, www.tpp.ch


Circle no. 156


Available as full units, the filter top or the storage flask only, the TPP vacuum filtration ‘rapid’ - Filtermax is available in sizes 150ml, 250ml, 500ml, and 1000ml. By this, the buyer receives the full flexibility.


Are you interested to test this exceptional product? Contact us today to find a TPP distributor in your country and to get a free sample: www.tpp.ch


Circle no. 157


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