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MASS SPECTROMETRY & SPECTROSCOPY


Nitrogen and Carbon in Steel with Improved Mobile Analyser


The latest version of Spectrotest from Spectro Analytical is the only mobile OES Spectrometer capable of segregating Duplex steels by Nitrogen content, and also the only one that can measure Carbon in steels down to 0.1% without the need for argon flushing. This is the latest step in a continuous process of product improvement since the first Spectrotest was introduced in 1979.


A number of advances in technology have made this possible. The “Plasma Generator” totally digital spark control accurately defines and controls the energy in the plasma, which significantly improves precision, reproducibility and measuring speed. The sample probe is new too: it is lighter, slimmer and more convenient to use when space is restricted. The patented new scrubbing system improves the optical performance to permit the measurement of Carbon in low alloy steels in air. An optional UV probe permits the measurement of light elements such as N, P, S, Be and B and can be interchanged with the standard probe in seconds. This advanced technology is combined with a rugged, compact but high performance optical system that uses the latest CCD detector technology. The Spectrotest also uses ICAL, Spectro’s Intelligent Calibration Logic, that monitors the instrument’s performance and automatically corrects for any calibration drift using a single control sample. For PMI, alloy grades are quickly identified against the instrument’s internal libraries. Another feature that makes the user’s task easier is APF (Automatic Programme Finding), which uses the measured spectrum to ensure that the best measurement parameters and programme are used for the sample.


Circle no. 36


New Titles from ILM Publications


A Practical Guide to


Implementing Clinical Mass Spectrometry Systems


A Practical Guide to Implementing Clinical


Mass Spectrometry Systems By Neil Leaver


Neil Leaver


The aim of this publication is to provide practical guidance for laboratories on the implementation of mass spectrometry into a clinical service where there might be limited expertise in the technique. This guidance is the author’s personal recommendation based on over ten years’ experience of clinical mass spectrometry.


ISBN: 978-1-906799-02-1 • January 2011 • Paperback • 96 pp Discounted price: £22.50 / $36 / €27 • (RRP: £25 / $40 / €30)


Monolithic Chromatography


and its Modern Applications Edited by Perry G. Wang, College Park, Maryland, USA


The use of monoliths in separation science has attracted a large amount of interest due to the enhanced speed and thoroughness with which they can separate complex mixtures of biological molecules. In this book, global experts comprehensively describe the synthesis and characterisation of the columns, as well as their numerous applications.


ISBN: 978-1-906799-03-8 • October 2010 • Hardback • 648 pp Discounted price: £162 / $243 / €198 • (RRP: £180 / $270 / €220)


Field Detection Technologies for Explosives


By Yin Sun, Advanced Analytical Technologies, USA


Fast and reliable equipment to detect the presence of explosives and explosive devices is critical to fighting terrorism. Written in a style that makes complicated technologies easy to understand, this book covers the principles, instrumentation and applications of current technologies used to detect explosives in the field. Both trace detection technologies and bulk detection technologies are discussed.


ISBN: 978-1-906799-02-1 • October 2010 • Hardback • 328 pp Discounted price: £108 / $162 / €130.50 • (RRP: £120 / $180 / €145)


ILM Publications’ books are available


from its online book shop, ILM Bookstore.com Ways to order


Online: www.ilmbookstore.com • Email: sales@ilmbookstore.com Phone your credit card order: +44 (0)1727 855574


High-Performance Separation and ESI Module Expands the Reach of Mass Spectrometry


The CESI 8000 High-Performance Separation-ESI Module with OptiMS Technology from Beckman Coulter, Inc consists of the first commercial CESI sprayer combined with new capillary electrophoresis instrumentation specifically designed for mass spectrometry (MS). It gives researchers a robust, high-sensitivity interface of capillary electrophoresis (CE) with MS, while providing a broad range of analyte coverage complementary to LC-MS and GC- MS. OptiMS Technology integrates an intrinsically low flow CE separation (as low as 10 nL/min.) with electrospray ionisation (ESI) in a single, dynamic process that takes place within a capillary. The new process is referred to as CESI, reflecting the combination. To achieve CESI, the distal end of the capillary is porous to ion flow, allowing the electrophoresis circuit to be bridged and ESI to be initiated within the same device.


CESI-MS is capable of generating separations of peptides with a high peak capacity (>320), allowing the analysis of very complex samples at the proteome level. The ultra-low flow rates used by CE effectively reduce ion suppression and make it possible to detect post- translational modifications (PTMs) like phosphorylation and sialylation, which typically hamper efficient ionisation.


High-separation efficiency and sensitivity permit the detection of peptides present in low abundance at concentrations in the picoMolar range. The selectivity of CE in front-end separation further enables the characterisation of intact proteins, their isoforms, cleaved fragments and complexes. CESI 8000 with OptiMS Technology from Beckman Coulter also provides fast and efficient separations of drugs, drug metabolites, organic acids, amino acids, low molecular weight amines, peptides, nucleic acids and nucleosides. Molecules often missed or altogether undetectable by technologies like reversed phase LC-MS, now become visible with CESI 8000. Easy switching between LC-ESI-MS and CESI-MS allows the addition of CESI to existing workflows. The CESI 8000 is installed on a height- adjustable, gear-driven portable lab bench so it can be rapidly set to the proper height of a mass spectrometer. Plug- and-spray adapters are available for top brand nanosources.


New Interferometer Key to Spectrometer


The WQF-510A FT-IR spectrometer from BFRL, manufacturer for spectroscopic and chromatographic instruments in China, features a new type of cube-corner Michelson interferometer that offers a smaller size and more compact structure, providing higher stability and less sensitivity to vibrations and thermal variation.


The fully sealed damp and dust proof interferometer ensures higher adaptability to the environment and increases accuracy and reliability in operation, while the isolated IR source and large space heat dissipation chamber design provides higher thermal stability - stable interference is obtained without the need of dynamic adjustment.


Furthermore, super wide sample compartment provides more flexibility to accommodate various accessories.


The company offers eight series of over 50 models of products, including atomic absorption spectrophotometers, atomic fluorescence spectrometers, FTIR spectrometers, UV/VIS spectrophotometers, optical emission spectrometers, microwave digestion system, gas chromatography and high performance liquid chromatography, all offered at a very competitive price. The instruments serve a wide range of industries such as pharmaceuticals, foods, chemical, petroleum, agriculture, metallurgy, geology and environmental protection.


Circle no. 37


Circle no. 38


INTERNATIONAL LABMATE - JULY 2011 - MASS SPECTROMETRY & SPECTROSCOPY


WWW.LABMATE-ONLINE.COM


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